phenobarbital has been researched along with Arrhythmias, Cardiac in 32 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital treatment decreased blood levels only prior to reaching equilibrium and did not alter the response to epinephrine-induced cardiac arrhythmias." | 5.26 | Effects of alterations in drug metabolism on chloroform-induced cardiac arrhythmias in rabbits. ( Carlson, GP, 1981) |
| "Enuresis is a common problem often treated effectively with imipramine hydrochloride." | 3.66 | Treatment of imipramine overdose in children. ( Cromie, WJ; Greene, AS, 1981) |
| "Rabbits treated with benzo(a)pyrene developed cardiac arrhythmias when exposed by inhalation to 8100 ppm trichloroethylene or 15000 ppm halothane to a greater extent and at lower doses of epinephrine challenge than did controls." | 3.66 | Cardiac arrhythmogenic action of benzo(a)pyrene in the rabbit. ( Carlson, GP; White, JF, 1983) |
| " Phenobarbital treatment slightly decreased blood levels of methylchloroform and the incidence of cardiac arrhythmias." | 3.66 | Effect of alterations in drug metabolism on epinephrine-induced cardiac arrhythmias in rabbits exposed to methylchloroform. ( Carlson, GP, 1981) |
| "Phenobarbital was observed to produce cardiovascular malformations in embryonic chicks." | 1.27 | The teratogenic effect of phenobarbital on the embryonic chick heart. ( Bruyere, HJ; Gilbert, EF; Matsuoka, R; Nishikawa, T; Takagi, Y, 1986) |
| "Phenobarbital pretreatment depressed heart rate, blood pressure and postganglionic cardiac sympathetic neural discharge." | 1.27 | Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat. ( Carnel, SB; Lathers, CM; Schraeder, PL, 1985) |
| "Phenobarbital treatment decreased blood levels only prior to reaching equilibrium and did not alter the response to epinephrine-induced cardiac arrhythmias." | 1.26 | Effects of alterations in drug metabolism on chloroform-induced cardiac arrhythmias in rabbits. ( Carlson, GP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (96.88) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MARTELLI, A | 1 |
| MICHEL, D | 1 |
| BOCK, K | 1 |
| HARTLEB, O | 1 |
| HERBST, M | 1 |
| SCHMIDT-VOIGT, J | 1 |
| KIMURA, E | 1 |
| LEVIN, J | 1 |
| BULL, AB | 1 |
| SEKIYA, A | 1 |
| VAUGHANWILLIAMS, EM | 1 |
| HARRIS, AS | 1 |
| KOKERNOT, RH | 1 |
| FROMMEL, E | 1 |
| BECK, IT | 1 |
| Greene, AS | 1 |
| Cromie, WJ | 1 |
| Carlson, GP | 5 |
| White, JF | 2 |
| Lathers, CM | 2 |
| Schraeder, PL | 2 |
| Carnel, SB | 2 |
| DeSilva, RA | 1 |
| Graboys, TB | 1 |
| Podrid, PJ | 1 |
| Lown, B | 1 |
| Azarbayjani, F | 1 |
| Danielsson, BR | 1 |
| Baudouy, P | 1 |
| Andreassian, B | 1 |
| Attuel, P | 1 |
| Greze, M | 1 |
| Soulie, J | 1 |
| Fruchaud, J | 1 |
| Eastwood, I | 1 |
| Forshaw, PJ | 1 |
| Jeyeratnam, J | 1 |
| Magos, L | 1 |
| Zamotaev, IP | 1 |
| Lozinskiĭ, LG | 1 |
| Sandomirskiĭ, BL | 1 |
| Data, JL | 1 |
| Wilkinson, GR | 1 |
| Nies, AS | 1 |
| Nishikawa, T | 1 |
| Bruyere, HJ | 1 |
| Takagi, Y | 1 |
| Gilbert, EF | 1 |
| Matsuoka, R | 1 |
| Tsueda, K | 1 |
| Jean-Francois, J | 1 |
| Richter, RW | 1 |
| Kaiser, H | 1 |
| Eisel, K | 1 |
| Herzfeld, R | 1 |
| Bigger, JT | 1 |
| Strauss, HC | 1 |
| Gassel, WD | 1 |
| Schneider, D | 1 |
| Siletchnik, LM | 1 |
| Kosh, JW | 1 |
| Appelt, GD | 1 |
| Chiche, P | 1 |
| Laruelle, P | 1 |
| Borgard, JP | 1 |
| Chassang, MF | 1 |
| Denizeau, JP | 1 |
| Emig, W | 1 |
2 reviews available for phenobarbital and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Cardioversion and defibrillation.
Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Catheterization; Diazepa | 1980 |
Digitalis toxicity: drug interactions promoting toxicity and the management of toxicity.
Topics: Adrenergic beta-Antagonists; Anesthetics; Anticholesteremic Agents; Arrhythmias, Cardiac; Cathartics | 1972 |
30 other studies available for phenobarbital and Arrhythmias, Cardiac
| Article | Year |
|---|---|
[Sparteine methiodide associated with phenylethylbarbituric acid in therapy of myocardial hyperexcitability; pharmacological study on the effect of sparteine methiodide].
Topics: Arrhythmias, Cardiac; Barbiturates; Humans; Myocardium; Phenobarbital; Sparteine | 1953 |
[Control of rhythmic disorders in cardiac catheterization by causat].
Topics: Arrhythmias, Cardiac; Atropine; Cardiac Catheterization; Catheterization; Heart Diseases; Niacin; Ni | 1957 |
[Extrasystolic heart rhythm disorders; practical viewpoints on diagnosis and therapy].
Topics: Arrhythmias, Cardiac; Humans; Phenobarbital; Plant Extracts; Procainamide; Quinidine; Vestibule, Lab | 1958 |
[ARRHYTHMIA].
Topics: Adrenal Cortex Hormones; Arrhythmias, Cardiac; Atropine; Diagnosis, Differential; Ephedrine; Epineph | 1963 |
TWO CASES OF BILATERAL PHAEOCHROMOCYTOMA WITH A DISCUSSION ON ANAESTHETIC MANAGEMENT OF CHROMATIN TUMOURS.
Topics: Adrenalectomy; Anesthesia; Anesthetics; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Child; | 1964 |
CENTRAL AND PERIPHRAL ACTIONS OF PRONETHALOL.
Topics: Arrhythmias, Cardiac; Blood Pressure; Chloroform; Electrocardiography; Epinephrine; Ethanolamines; E | 1965 |
Effects of diphenylhydantoin sodium (dilantin sodium) and phenobarbital sodium upon ectopic ventricular tachycardia in acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Barbital; Heart; Hydantoins; Myocardial Infarction; Phenobarbital; Phenytoin; | 1950 |
[The combination of phenobarbital and quinidine in the treatment of cardiovascular, autonomic cardiac neuroses extrasystoles, paroxysmal tachycardia].
Topics: Arrhythmias, Cardiac; Autonomic Nervous System; Barbiturates; Cardiac Complexes, Premature; Cardiova | 1948 |
Treatment of imipramine overdose in children.
Topics: Adult; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Preschool; Coma; Diazepam; Drug Administrat | 1981 |
Cardiac arrhythmogenic action of benzo(a)pyrene in the rabbit.
Topics: Animals; Arrhythmias, Cardiac; Benzo(a)pyrene; Benzopyrenes; Epinephrine; Ethylene Chlorohydrin; Hal | 1983 |
Intracranial haemorrhage.
Topics: Arrhythmias, Cardiac; Cerebral Hemorrhage; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Humans; | 1983 |
Neural mechanisms in cardiac arrhythmias associated with epileptogenic activity: the effect of phenobarbital in the cat.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Disease Models, Anima | 1984 |
Effects of alterations in drug metabolism on chloroform-induced cardiac arrhythmias in rabbits.
Topics: Animals; Arrhythmias, Cardiac; Biphenyl Compounds; Chloroform; Cytochrome P-450 Enzyme System; Dieth | 1981 |
Effect of alterations in drug metabolism on epinephrine-induced cardiac arrhythmias in rabbits exposed to methylchloroform.
Topics: Animals; Antimetabolites; Arrhythmias, Cardiac; Biphenyl Compounds; Cytochrome P-450 Enzyme System; | 1981 |
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; | 1998 |
[Romano-Ward syndrome and left stellectomy. General review apropos of a recent case].
Topics: Adult; Arrhythmias, Cardiac; Deafness; Diagnosis, Differential; Drug Therapy, Combination; Electroca | 1977 |
Influence of alterations in drug metabolism on spontaneous and epinephrine-induced cardiac arrhythmias in animals exposed to trichloroethylene.
Topics: Animals; Aroclors; Arrhythmias, Cardiac; Biphenyl Compounds; Diethylamines; Drug Interactions; Elect | 1979 |
Cardiac sensitization induced by phenobarbitone and prolonged by CS2.
Topics: Animals; Arrhythmias, Cardiac; Carbon Disulfide; Drug Synergism; Male; Norepinephrine; Phenobarbital | 1977 |
[Treatment of cardiac rhythm disorders with pulsnorm].
Topics: Adolescent; Adult; Aged; Ajmaline; Antazoline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Co | 1975 |
Interaction of quinidine with anticonvulsant drugs.
Topics: Adult; Arrhythmias, Cardiac; Depression, Chemical; Drug Interactions; Enzyme Induction; Epilepsy; Fe | 1976 |
The teratogenic effect of phenobarbital on the embryonic chick heart.
Topics: Abnormalities, Drug-Induced; Animals; Arrhythmias, Cardiac; Chick Embryo; Dose-Response Relationship | 1986 |
Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electrocardio | 1985 |
Cardiac standstill in tetanus: review of seven consecutive cases.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Arrest; Heroin Dependence; Humans; H | 1973 |
[Oral treatment of heart rhythm disorders with active substance combination, Pulsnorma].
Topics: Adolescent; Adult; Aged; Arrhythmia, Sinus; Arrhythmias, Cardiac; Electrocardiography; Female; Hista | 1967 |
[Treatment of heart rhythm disorders in general practice].
Topics: Adult; Aged; Arrhythmias, Cardiac; Drug Synergism; Electrocardiography; Histamine H1 Antagonists; Hu | 1969 |
[Acute drug allergic thrombocytopenia caused by antazoline].
Topics: Aged; Ajmaline; Aniline Compounds; Arrhythmias, Cardiac; Benzyl Compounds; Bone Marrow Examination; | 1974 |
Cardiac sensitizing effects of 1,1-dichloroethylene: enhancement by phenobarbital pretreatment.
Topics: Animals; Arrhythmias, Cardiac; Drug Synergism; Electrocardiography; Epinephrine; Ethylenes; Heart; H | 1974 |
Selected pharmacological studies of succinic semialdehyde.
Topics: Aldehydes; Animals; Arrhythmias, Cardiac; Blood Pressure; Central Nervous System; Chromatography, Ga | 1972 |
[Diphenylhydantoin: study of plasmatic concentrations obtained by oral administration and of their antiarrhythmic effects].
Topics: Administration, Oral; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Synergism; Humans | 1973 |
[On the drug therapy of arrhytmias].
Topics: Arrhythmias, Cardiac; Humans; Meprobamate; Phenobarbital; Phytotherapy; Plants, Medicinal; Procainam | 1966 |