phenobarbital has been researched along with Apnea in 21 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea." | 7.73 | [High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006) |
| "To determine the effect of phenobarbital sodium therapy and subependymal intraventricular hemorrhage (SEp-IVH) on the theophylline requirement of premature infants suffering with apnea and seizure activity, we compared three groups of patients as follows: group 1, those with apnea of prematurity (ten patients); group 2, those with apnea and SEp-IVH (ten patients); and group 3, those with apnea, SEp-IVH, and seizure activity for which they were receiving phenobarbital therapy (nine patients)." | 7.67 | Phenobarbital increases the theophylline requirement of premature infants being treated for apnea. ( Gottschalk, SK; Kissling, GE; Schuth, CR; Tran, TH; Yazdani, M, 1987) |
| "Polygraphic recordings were performed in seven preterm infants who had been given phenobarbital (phenobarbitone) to evaluate its effect on neonatal sleep behavior and on the incidence of neurogenic apnea and/or bradycardia." | 7.65 | Rapid eye movement sleep, apnea, and cardiac slowing influenced by phenobarbital administration in the neonate. ( Albani, M; Gabriel, M, 1977) |
| "An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea." | 3.73 | [High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006) |
| " He manifested apnea during the first 12 hours of life." | 3.72 | Temporal lobe hemorrhage in the full-term neonate presenting as apneic seizures. ( Goodkin, HP; Tramonte, JJ, 2004) |
| "Thirteen treatment failures and ten instances of apnea occurred among the 28 patients treated with benzodiazepine/phenobarbital." | 3.68 | Management of hyponatremic seizures in children with hypertonic saline: a safe and effective strategy. ( Fleischmann, L; Hackbarth, R; Meert, K; Sarnaik, AP, 1991) |
| " Clinical diagnosis was determined neurologically and included (1) coma, (2) apnea, manifested by inability to sustain respiration, and (3) absent brainstem reflexes." | 3.67 | Brain death in the newborn. ( Ashwal, S; Schneider, S, 1989) |
| "To determine the effect of phenobarbital sodium therapy and subependymal intraventricular hemorrhage (SEp-IVH) on the theophylline requirement of premature infants suffering with apnea and seizure activity, we compared three groups of patients as follows: group 1, those with apnea of prematurity (ten patients); group 2, those with apnea and SEp-IVH (ten patients); and group 3, those with apnea, SEp-IVH, and seizure activity for which they were receiving phenobarbital therapy (nine patients)." | 3.67 | Phenobarbital increases the theophylline requirement of premature infants being treated for apnea. ( Gottschalk, SK; Kissling, GE; Schuth, CR; Tran, TH; Yazdani, M, 1987) |
| "Polygraphic recordings were performed in seven preterm infants who had been given phenobarbital (phenobarbitone) to evaluate its effect on neonatal sleep behavior and on the incidence of neurogenic apnea and/or bradycardia." | 3.65 | Rapid eye movement sleep, apnea, and cardiac slowing influenced by phenobarbital administration in the neonate. ( Albani, M; Gabriel, M, 1977) |
| " Qualitative and quantitative differences in pharmacokinetics and pharmacodynamics of drugs should be considered before dosage regimens can be established." | 1.27 | [Peculiarities of drug therapy in childhood]. ( Kusenbach, G; Reinhardt, D, 1986) |
| "EEG seizures were recorded in seven patients, five of whom had experienced clinical seizures in the 24 hours prior to cassette EEG recording." | 1.27 | Cassette electroencephalography in the evaluation of neonatal seizures. ( Bridgers, SL; Ebersole, JS; Ehrenkranz, RA; Ment, LR; Silva, CG, 1986) |
| " At the moment, xanthines are the drugs of choice, since they are both effective and safe, provided dosage is adjusted to each patient." | 1.26 | [Drug treatment of apnoea in premature infants (author's transl)]. ( Klethi, J; Mack, G; Messer, J; Willard, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kharoshankaya, L | 1 |
| Murray, DM | 1 |
| Bogue, C | 1 |
| Ahearne, C | 1 |
| Murphy, BP | 1 |
| Boylan, GB | 1 |
| Toomes, M | 1 |
| Maleck, WH | 1 |
| Koetter, KP | 1 |
| Petroianu, GA | 1 |
| WARTER, J | 1 |
| MANTZ, JM | 1 |
| METAIS, P | 1 |
| HAMMANN, B | 1 |
| KURTZ, D | 1 |
| HERBERG, D | 1 |
| GEISLER, L | 1 |
| SCHENCK, P | 1 |
| MAURY, H | 1 |
| Tramonte, JJ | 1 |
| Goodkin, HP | 1 |
| Bauer, J | 1 |
| Hayashi, T | 1 |
| Kubota, M | 1 |
| Mimaki, M | 1 |
| Tomita, S | 1 |
| Horio, K | 1 |
| Griffith, PA | 1 |
| Karp, HR | 1 |
| Willard, D | 1 |
| Mack, G | 1 |
| Messer, J | 1 |
| Klethi, J | 1 |
| van Putten, MJ | 1 |
| Bosman-Vermeeren, JM | 1 |
| Brouwer, OF | 1 |
| Gabriel, M | 1 |
| Albani, M | 1 |
| Edel'shteĭn, EA | 1 |
| Bondarenko, ES | 1 |
| Mumladze, TA | 1 |
| Madden, JD | 1 |
| Sarnaik, AP | 1 |
| Meert, K | 1 |
| Hackbarth, R | 1 |
| Fleischmann, L | 1 |
| Ashwal, S | 1 |
| Schneider, S | 1 |
| Wilschanski, M | 1 |
| Kaplan, M | 1 |
| Lhermitte, M | 1 |
| Houdret, N | 1 |
| Broly, F | 1 |
| Roussel, P | 1 |
| Carpentier, C | 1 |
| Zaoui, C | 1 |
| Lequien, P | 1 |
| Yazdani, M | 1 |
| Kissling, GE | 1 |
| Tran, TH | 1 |
| Gottschalk, SK | 1 |
| Schuth, CR | 1 |
| Reinhardt, D | 1 |
| Kusenbach, G | 1 |
| Bridgers, SL | 1 |
| Ebersole, JS | 1 |
| Ment, LR | 1 |
| Ehrenkranz, RA | 1 |
| Silva, CG | 1 |
1 review available for phenobarbital and Apnea
| Article | Year |
|---|---|
[Central apnea in newborns].
Topics: Acetazolamide; Anticonvulsants; Apnea; Arnold-Chiari Malformation; Diagnosis, Differential; DiGeorge | 1999 |
20 other studies available for phenobarbital and Apnea
| Article | Year |
|---|---|
Early EEG findings in tuberous sclerosis complex presenting with apneic seizures soon after birth.
Topics: Anticonvulsants; Apnea; Electroencephalography; Humans; Infant, Newborn; Magnetic Resonance Imaging; | 2016 |
Out-of-hospital management of benzodiazepine-resistant status epilepticus in a child with Wolf-Hirschhorn syndrome.
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Child; Chromosome Deletion; Chromosomes, Human, Pai | 2003 |
[Prolonged coma (10 days) due to massive phenobarbital (25 g) poisoning: prolonged apnea (4 days); artificial respiration. Recovery].
Topics: Apnea; Barbiturates; Cardiac Glycosides; Cell Respiration; Chloroform; Coma; Humans; Phenobarbital; | 1963 |
[ON THE INFLUENCE OF SOME FREQUENTLY USED SEDATIVES AND ANALGESICS ON THE HUMAN RESPIRATORY CENTER WITH SPECIAL REFERENCE TO PATIENTS WITH ALVEOLAR HYPOVENTILATION].
Topics: Analgesics; Apnea; Humans; Hypnotics and Sedatives; Hypoventilation; Medulla Oblongata; Meperidine; | 1963 |
[A CASE OF TETANUS].
Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Apnea; Ascorbic Acid; Calcium; Gluconates; Huma | 1963 |
Temporal lobe hemorrhage in the full-term neonate presenting as apneic seizures.
Topics: Adult; Apnea; Cerebral Hemorrhage; Electroencephalography; Female; Humans; Infant, Newborn; Magnetic | 2004 |
[Attacks of apnea in a newborn aged 18 days].
Topics: Apnea; Cheyne-Stokes Respiration; Electroencephalography; Homeopathy; Humans; Infant, Newborn; Male; | 2006 |
[High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome].
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Cough; Humans; Infant, Newborn; Male; Phenobarbital | 2006 |
Lorazepam in therapy for status epilepticus.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Apnea; Drug Therapy, Combination; Humans; Hypotension; Loraz | 1980 |
[Drug treatment of apnoea in premature infants (author's transl)].
Topics: Apnea; Chemoreceptor Cells; Doxapram; Humans; Infant, Newborn; Infant, Premature, Diseases; Neurotra | 1981 |
Rapid eye movement sleep, apnea, and cardiac slowing influenced by phenobarbital administration in the neonate.
Topics: Apnea; Female; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Phenobarbital | 1977 |
[Lesions of the nervous system in premature children with "conjugated" jaundices].
Topics: Apnea; Eye Manifestations; Face; Humans; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neo | 1979 |
Problems pertaining to the care of newborn infants of drug-addicted women.
Topics: Apnea; Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Narcotics; P | 1978 |
Management of hyponatremic seizures in children with hypertonic saline: a safe and effective strategy.
Topics: Adolescent; Anticonvulsants; Apnea; Benzodiazepines; Brain Chemistry; Brain Diseases; Child; Child, | 1991 |
Brain death in the newborn.
Topics: Apnea; Brain; Brain Death; Brain Stem; Cerebrovascular Circulation; Coma; Electroencephalography; Hu | 1989 |
Phenobarbital increases aminophylline requirement in premature infants.
Topics: Aminophylline; Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Seizures | 1988 |
Simultaneous administration of caffeine and phenobarbitone in infants with apnea.
Topics: Apnea; Caffeine; Drug Therapy, Combination; Half-Life; Humans; Infant; Infant, Newborn; Infant, Prem | 1987 |
Phenobarbital increases the theophylline requirement of premature infants being treated for apnea.
Topics: Apnea; Cerebral Hemorrhage; Drug Interactions; Humans; Infant, Newborn; Infant, Premature; Phenobarb | 1987 |
[Peculiarities of drug therapy in childhood].
Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; | 1986 |
Cassette electroencephalography in the evaluation of neonatal seizures.
Topics: Apnea; Electroencephalography; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Se | 1986 |