phenobarbital has been researched along with Anemia in 25 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sensitivity to phenobarbital and related anticonvulsants may induce life-threatening leukopenia, thrombocytopenia, and anemia in dogs." | 3.70 | Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants. ( Calvert, C; Jacobs, G; Kaufman, A, 1998) |
| "A prospective study was undertaken to determine the cause of the acute anemia previously observed in pigs manifesting acute liver necrosis after administration of acetaminophen in dosages in excess of the LD100." | 3.65 | Experimental liver necrosis: hepatic erythrocyte sequestration as a cause of acute anemia. ( Fiskerstrand, C; Miller, DJ; Pichanick, GG; Saunders, SJ, 1977) |
| "Features of both systemic lupus erythematosus and scleroderma developed in a young Chinese girl while on multiple anticonvulsant therapy." | 1.25 | Lupus-scleroderma syndrome induced by ethosuximide. ( Chan, HL; Teoh, PC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (80.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, TN | 1 |
| Bailin, HG | 1 |
| Jutkowitz, LA | 1 |
| Scott, MA | 1 |
| Lucidi, CA | 1 |
| Yasuda, M | 1 |
| Desnick, RJ | 1 |
| Lakhoua, G | 1 |
| Aouinti, I | 1 |
| Sahnoun, R | 1 |
| Kastalli, S | 1 |
| Daghfous, R | 1 |
| Zaïem, A | 1 |
| FORSHAW, JW | 1 |
| BENIANS, RC | 1 |
| HUNTER, RA | 1 |
| HAWKINS, CF | 1 |
| MEYNELL, MJ | 1 |
| CHANARIN, I | 1 |
| LAIDLAW, J | 1 |
| LOUGHRIDGE, LW | 1 |
| MOLLIN, DL | 1 |
| DOIG, A | 1 |
| STANTON, JB | 1 |
| LONG, MT | 1 |
| CHILDRESS, RH | 1 |
| BOND, WH | 1 |
| MENZIES, DN | 1 |
| KLIPSTEIN, FA | 1 |
| NAKAMURA, H | 1 |
| ANAND, MP | 1 |
| RYDER, RJ | 1 |
| HANSEN, HA | 1 |
| NORDQVIST, P | 1 |
| SOURANDER, P | 1 |
| MACINTOSH, PC | 1 |
| HUTCHISON, JL | 1 |
| SHERWIN, AL | 1 |
| WAIT, RH | 1 |
| COOPER, BA | 1 |
| Khoutorsky, A | 1 |
| Bruchim, Y | 1 |
| Jacobs, G | 1 |
| Calvert, C | 1 |
| Kaufman, A | 1 |
| Teoh, PC | 1 |
| Chan, HL | 1 |
| Miller, DJ | 1 |
| Pichanick, GG | 1 |
| Fiskerstrand, C | 1 |
| Saunders, SJ | 1 |
| Edwards, JA | 1 |
| Hoke, JE | 1 |
| Shahidi, NT | 1 |
| Brooks, SM | 1 |
| Giannì, E | 1 |
| Bracchetti, A | 1 |
| Rivlin, RS | 1 |
| Wagner, HN | 1 |
1 review available for phenobarbital and Anemia
| Article | Year |
|---|---|
Murine models of the human porphyrias: Contributions toward understanding disease pathogenesis and the development of new therapies.
Topics: Anemia; Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Gen | 2019 |
24 other studies available for phenobarbital and Anemia
| Article | Year |
|---|---|
Bone marrow, blood, and clinical findings in dogs treated with phenobarbital.
Topics: Anemia; Animals; Bone Marrow; Dog Diseases; Dogs; Hematologic Diseases; Phenobarbital | 2021 |
A hemophagocytosis syndrome attributed to phenobarbital.
Topics: Anemia; Anticonvulsants; Autoimmune Diseases; Diagnosis, Differential; Drug Hypersensitivity Syndrom | 2016 |
Megaloblastic anaemia associated with anticonvulsant therapy.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenobarbital | 1957 |
Megaloblastic anaemia occurring during treatment of epilepsy with phenytoin sodium, primidone and phenobarbitone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenyto | 1957 |
Macrocytosis and macrocytic anaemia caused by anticonvulsant drugs.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Erythrocytes; Hematologic Diseases; Humans; Hydantoins; | 1958 |
Megaloblastic anaemia due to phenobarbitone; the convulsant action of therapeutic doses of folic acid.
Topics: Anemia; Anemia, Megaloblastic; Convulsants; Folic Acid; Phenobarbital; Tracheophyta | 1960 |
Megaloblastic anaemia during combined phensuximide and phenobarbitone therapy.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Epilepsy; Phenobarbital; Succinimides | 1961 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE USE OF ANTICONVULSANT DRUGS. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenobarbita | 1963 |
CONTROLLED TRIAL OF CHLOROTHIAZIDE IN TREATMENT OF EARLY PRE-ECLAMPSIA.
Topics: Albuminuria; Anemia; Chlorothiazide; Diet; Diet Therapy; Female; Humans; Outpatient Clinics, Hospita | 1964 |
SUBNORMAL SERUM FOLATE AND MACROCYTOSIS ASSOCIATED WITH ANTICONVULSANT DRUG THERAPY.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood Chemical Analysis; Enterococcus | 1964 |
[A STUDY ON THE SO-CALLED ATYPICAL LYMPHOCYTE WITH SPECIAL REFERENCE TO PHASE CONTRAST MICROSCOPY].
Topics: Anemia; Blood; Bone Marrow Diseases; Collagen Diseases; Coombs Test; Hodgkin Disease; Infectious Mon | 1963 |
IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Brain Diseases; Cysticercosis; Drug Therapy; Epil | 1964 |
HAEMORRHAGE ASSOCIATED WITH THROMBOCYTOPENIA IN MEGALOBLASTIC ANAEMIA.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Blood Platelet Disorders; Drug Therapy; Epilepsy; | 1964 |
MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Avitaminosis; Barbiturates; Brai | 1964 |
Megaloblastic anaemia due to anticonvulsant therapy: report of a case responding to vitamin B12.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Corrinoids; Hematinics; Humans; Hydantoins; Phenobar | 1960 |
Megaloblastic anaemia associated with phenobarbital therapy.
Topics: Anemia; Anemia, Megaloblastic; Humans; Phenobarbital; Tracheophyta | 1960 |
Transient leucopenia, thrombocytopenia and anaemia associated with severe acute phenobarbital intoxication in a dog.
Topics: Anemia; Animals; Anti-Anxiety Agents; Dog Diseases; Dogs; Leukopenia; Male; Phenobarbital; Thrombocy | 2008 |
Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants.
Topics: Anemia; Animals; Anticonvulsants; Bacteremia; Blood Cell Count; Dog Diseases; Dogs; Female; Male; Ne | 1998 |
Lupus-scleroderma syndrome induced by ethosuximide.
Topics: Adolescent; Anemia; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Lupus Erythematosus, Syste | 1975 |
Experimental liver necrosis: hepatic erythrocyte sequestration as a cause of acute anemia.
Topics: Acetaminophen; Acute Disease; Anemia; Animals; Chemical and Drug Induced Liver Injury; Erythrocytes; | 1977 |
Effect of dietary iron manipulation and phenobarbitone treatment on in vivo intestinal absorption of iron in mice with sex-linked anemia.
Topics: Anemia; Animals; Deficiency Diseases; Intestinal Absorption; Iron; Iron Deficiencies; Male; Mice; Mi | 1975 |
Barbiturate effect in androgen therapy.
Topics: Androgens; Anemia; Animals; Barbiturates; Biotransformation; Enzyme Induction; Humans; Phenobarbital | 1972 |
[Contribution to the pathogenesis of gingival hypertrophy due to diphenylhydantoin in experiments on animals].
Topics: Anemia; Animals; Drug Synergism; FIGLU Test; Folic Acid; Gingival Hypertrophy; Phenobarbital; Phenyt | 1968 |
Anemia in hyperthyroidism.
Topics: Adolescent; Adult; Aged; Anemia; Erythrocyte Aging; Female; Humans; Hyperthyroidism; Iron; Male; Mid | 1969 |