phenobarbital has been researched along with Anemia, Hypochromic in 7 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Anemia, Hypochromic: Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Well-known toxic effects of PB on the liver and thyroid were observed in a dose-dependent manner, along with altered lipid, glucose, and electrolyte metabolism." | 1.35 | Multiple organ toxicity, including hypochromic anemia, following repeated dose oral administration of phenobarbital (PB) in rats. ( Enomoto, A; Harada, T; Ishizuka, K; Kawakatsu, H; Kojima, S; Kosaka, T; Nakashima, N; Saka, M; Sasaki, J; Tomita, M; Yoshida, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conway, AJ | 1 |
| Brown, FC | 1 |
| Fullinfaw, RO | 1 |
| Kile, BT | 1 |
| Jane, SM | 1 |
| Curtis, DJ | 1 |
| Kojima, S | 1 |
| Sasaki, J | 1 |
| Tomita, M | 1 |
| Saka, M | 1 |
| Ishizuka, K | 1 |
| Kawakatsu, H | 1 |
| Yoshida, T | 1 |
| Kosaka, T | 1 |
| Enomoto, A | 1 |
| Nakashima, N | 1 |
| Harada, T | 1 |
| Yoshiji, H | 1 |
| Nakae, D | 1 |
| Kinugasa, T | 1 |
| Matsuzaki, M | 1 |
| Denda, A | 1 |
| Tsujii, T | 1 |
| Konishi, Y | 1 |
| Becking, GC | 1 |
| Sorbie, J | 1 |
| Hamilton, DL | 1 |
| Valberg, LS | 1 |
| Montgomery, MR | 1 |
| Erickson, RR | 1 |
| Holtzman, JL | 1 |
| Landaw, SA | 1 |
7 other studies available for phenobarbital and Anemia, Hypochromic
| Article | Year |
|---|---|
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen.
Topics: Anemia, Hypochromic; Animals; Base Sequence; Biosynthetic Pathways; Coproporphyria, Hereditary; Copr | 2017 |
Multiple organ toxicity, including hypochromic anemia, following repeated dose oral administration of phenobarbital (PB) in rats.
Topics: Administration, Oral; Anemia, Hypochromic; Animals; Body Weight; Eating; Female; Gait; Iron; Liver; | 2009 |
Inhibitory effect of dietary iron deficiency on the induction of putative preneoplastic foci in rat liver initiated with diethylnitrosamine and promoted by phenobarbital.
Topics: Anemia, Hypochromic; Animals; Body Weight; Diethylnitrosamine; Enzyme Induction; gamma-Glutamyltrans | 1991 |
Influence of dietary iron levels on hepatic drug metabolism in vivo and in vitro in the rat.
Topics: Aminopyrine; Anemia, Hypochromic; Aniline Compounds; Animals; Body Weight; Cytochrome c Group; Cytoc | 1972 |
Effect of various factors on iron absorption in mice with X-linked anaemia.
Topics: Administration, Oral; Anemia, Hypochromic; Animals; Ascorbic Acid; Biological Transport; Body Weight | 1974 |
In vivo enrichment of hepatic microsomes with isotopic iron.
Topics: Anemia, Hypochromic; Animals; Body Weight; Cytochromes; Deficiency Diseases; Dose-Response Relations | 1974 |
Kinetic aspects of endogenous carbon monoxide production in experimental animals.
Topics: Acetamides; Allyl Compounds; Anemia, Hypochromic; Animals; Birds; Blood Transfusion; Carbon Isotopes | 1970 |