phenobarbital has been researched along with Amyotonia Congenita in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For the former, the MES test, clonic seizures induced by pentylenetetrazol, 90 mg/kg, s." | 1.26 | Differential selectivity of several barbiturates on experimental seizures and neurotoxicity in the mouse. ( Blake, GJ; Gilbert, MB; Raines, A; Richardson, B, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, Y | 1 |
| Raines, A | 1 |
| Blake, GJ | 1 |
| Richardson, B | 1 |
| Gilbert, MB | 1 |
| Cocchiarella, A | 1 |
| Downey, JA | 1 |
| Darling, RC | 1 |
1 review available for phenobarbital and Amyotonia Congenita
| Article | Year |
|---|---|
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fruc | 2007 |
1 trial available for phenobarbital and Amyotonia Congenita
| Article | Year |
|---|---|
Evaluation of the effect of diazepam on spasticity.
Topics: Adult; Aged; Diazepam; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Moto | 1967 |
1 other study available for phenobarbital and Amyotonia Congenita
| Article | Year |
|---|---|
Differential selectivity of several barbiturates on experimental seizures and neurotoxicity in the mouse.
Topics: Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Male; Mice; Neuromuscular Disease | 1979 |