Page last updated: 2024-11-02

phenobarbital and Amelia

phenobarbital has been researched along with Amelia in 2 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"We report a stillborn, GA/LMP = 37 weeks, delivered by an epileptic woman, who received in the first four months of pregnancy phenobarbital (PH) 0."7.79Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy. ( Brailoiu, CG; Cernea, N; Tica, AA; Tica, OS; Tica, VI, 2013)
"We report a stillborn, GA/LMP = 37 weeks, delivered by an epileptic woman, who received in the first four months of pregnancy phenobarbital (PH) 0."3.79Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy. ( Brailoiu, CG; Cernea, N; Tica, AA; Tica, OS; Tica, VI, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tica, OS1
Tica, AA1
Brailoiu, CG1
Cernea, N1
Tica, VI1
Super, M1
Muller, A1

Other Studies

2 other studies available for phenobarbital and Amelia

ArticleYear
Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy.
    Birth defects research. Part A, Clinical and molecular teratology, 2013, Volume: 97, Issue:6

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Ectromelia; Epilepsy; Fatal Outcome; Female; Humans; Phe

2013
Phocomelia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Apr-15, Volume: 46, Issue:16

    Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; P

1972