phenobarbital has been researched along with Alcohol Problem in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital and LZ were similarly effective in the treatment of mild/moderate alcohol withdrawal in the ED and at 48 hours." | 2.76 | A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal. ( Barnes, RL; Dery, RA; Hendey, GW; Mentler, P; Snowden, B, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahmoud, S | 1 |
| Anderson, E | 1 |
| Vosooghi, A | 1 |
| Herring, AA | 1 |
| Hendey, GW | 1 |
| Dery, RA | 1 |
| Barnes, RL | 1 |
| Snowden, B | 1 |
| Mentler, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for phenobarbital and Alcohol Problem
| Article | Year |
|---|---|
A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal.
Topics: Administration, Oral; Alcohol-Related Disorders; Chlordiazepoxide; Female; GABA Modulators; Humans; | 2011 |
1 other study available for phenobarbital and Alcohol Problem
| Article | Year |
|---|---|
Treatment of opioid and alcohol withdrawal in a cohort of emergency department patients.
Topics: Adult; Aged; Alcohol-Related Disorders; Buprenorphine; Emergency Service, Hospital; Female; Humans; | 2021 |