phenobarbital has been researched along with Alcohol Drinking in 20 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The volatility and lipophilicity by which organic solvents are distinct from other chemicals constitute a characteristic pharmacokinetic feature." | 2.37 | Pharmacokinetics of organic solvent vapors in relation to their toxicity. ( Nakajima, T; Sato, A, 1987) |
| " This mechanism may be significant for the clinical dosage of patients with alcohol dependence." | 1.48 | Molecular spectroscopic studies examining the interactions between phenobarbital and human serum albumin in alcohol consumption. ( Cui, SF; Li, W; Zhou, CH, 2018) |
| "Phenobarbital (PB) was administered to a positive control group by oral gavage at a daily dose of 80 mg kg(-1)." | 1.36 | Tertiary butyl alcohol in drinking water induces phase I and II liver enzymes with consequent effects on thyroid hormone homeostasis in the B6C3F1 female mouse. ( Banton, M; Blanck, O; Espinasse-Lormeau, H; Fowles, J; Pallen, C; Schorsch, F; Schulte-Koerne, E; Totis, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, SF | 1 |
| Li, W | 1 |
| Zhou, CH | 1 |
| Blanck, O | 1 |
| Fowles, J | 1 |
| Schorsch, F | 1 |
| Pallen, C | 1 |
| Espinasse-Lormeau, H | 1 |
| Schulte-Koerne, E | 1 |
| Totis, M | 1 |
| Banton, M | 1 |
| SCHMIDT, H | 1 |
| KLEINMAN, KM | 1 |
| Rumack, BH | 1 |
| Kostrubsky, VE | 1 |
| Strom, SC | 1 |
| Wood, SG | 1 |
| Wrighton, SA | 1 |
| Sinclair, PR | 1 |
| Sinclair, JF | 1 |
| Seixas, FA | 1 |
| Rondeau, DB | 1 |
| Wayner, MJ | 1 |
| Jolicoeur, FB | 1 |
| Dwoskin, LP | 1 |
| Marselos, M | 1 |
| Eriksson, K | 1 |
| Hänninen, O | 1 |
| Miller, RR | 1 |
| Allan, AM | 1 |
| Mayes, GG | 1 |
| Draski, LJ | 1 |
| Fikr, V | 1 |
| Budka, I | 1 |
| Stika, L | 1 |
| Sato, A | 2 |
| Nakajima, T | 2 |
| Kramer, S | 1 |
| Ward, E | 1 |
| Meadows, AT | 1 |
| Malone, KE | 1 |
| Okino, T | 1 |
| Bailey, DN | 1 |
| Jatlow, PI | 1 |
| Deitrich, RA | 1 |
| Freund, G | 1 |
| Beckett, AH | 1 |
| Vesell, ES | 1 |
| Page, JG | 1 |
3 reviews available for phenobarbital and Alcohol Drinking
| Article | Year |
|---|---|
Acetaminophen misconceptions.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Interactions; Humans; Liver; Phenoba | 2004 |
Pharmacokinetics of organic solvent vapors in relation to their toxicity.
Topics: Alcohol Drinking; Drug Interactions; Food; Humans; Kinetics; Lung; Occupational Medicine; Phenobarbi | 1987 |
Effects of drug-drug and drug-food interaction on drug levels and performance in man.
Topics: Alcohol Drinking; Amphetamine; Animals; Animals, Laboratory; Behavior; Diet; Drug Interactions; Envi | 1970 |
17 other studies available for phenobarbital and Alcohol Drinking
| Article | Year |
|---|---|
Molecular spectroscopic studies examining the interactions between phenobarbital and human serum albumin in alcohol consumption.
Topics: Alcohol Drinking; Drug Interactions; Ethanol; Humans; Molecular Docking Simulation; Phenobarbital; S | 2018 |
Tertiary butyl alcohol in drinking water induces phase I and II liver enzymes with consequent effects on thyroid hormone homeostasis in the B6C3F1 female mouse.
Topics: Alcohol Drinking; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dose-Response Re | 2010 |
EFFECT OF CHRONIC ADMINISTRATION AND WITHDRAWAL OF BARBITURATES UPON DRINKING IN THE RAT.
Topics: Alcohol Drinking; Barbiturates; Phenobarbital; Rats; Research; Substance Withdrawal Syndrome; Substa | 1964 |
Ethanol and isopentanol increase CYP3A and CYP2E in primary cultures of human hepatocytes.
Topics: Adolescent; Adult; Alcohol Drinking; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP2E1; Cy | 1995 |
Drug/alcohol interactions: avert potential dangers.
Topics: Aged; Aging; Alcohol Drinking; Alcoholism; Antidepressive Agents, Tricyclic; Aspirin; California; Di | 1979 |
The effects of sodium phenobarbital on voluntary ethanol consumption in rats.
Topics: Alcohol Drinking; Amobarbital; Animals; Barbital; Drinking Behavior; Male; Phenobarbital; Rats | 1977 |
Aldehyde dehydrogenase inducibility and ethanol preference in rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcohol Oxidoreductases; Animals; Ascorbic Acid; Cytosol; Drinking B | 1975 |
Effects of smoking on drug action.
Topics: Adult; Aged; Aging; Alcohol Drinking; Dextropropoxyphene; Dose-Response Relationship, Drug; Female; | 1977 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Ac | 1991 |
[Possibilities of modelling of an undesirable phenomenon-- non-alcoholic substance abuse in society].
Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Caffeine; Child; Codeine; Czechoslovakia; Drug Combina | 1988 |
Medical and drug risk factors associated with neuroblastoma: a case-control study.
Topics: Alcohol Drinking; Antiemetics; Coffee; Diuretics; Female; Fetus; Gonadal Steroid Hormones; Hair Dyes | 1987 |
Kinetic studies on benzene metabolism in rat liver--possible presence of three forms of benzene metabolizing enzymes in the liver.
Topics: Alcohol Drinking; Animals; Benzene; Biotransformation; Ethanol; Food Deprivation; Isoenzymes; Kineti | 1987 |
Methaqualone overdose: analytical methodology, and the significance of serum drug concentrations.
Topics: Alcohol Drinking; Alkanes; Chloroform; Chromatography, Gas; Chromatography, Thin Layer; Consciousnes | 1973 |
Genetic basis of phenobarbital-induced increase in aldehyde dehydrogenase: implications for alcohol research.
Topics: Alcohol Drinking; Alcoholism; Aldehydes; Animals; Enzyme Induction; Genotype; Humans; Inbreeding; Li | 1972 |
Alcohol, barbiturate, and bromide withdrawal syndromes in mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Barbiturates; Body Weight; Bromides; Diet; Disease Models, An | 1973 |
Clinical depression of the central nervous system due to diazepam and chlordiazepoxide in relation to cigarette smoking and age.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Anxiety; Brain; Chlordiazepoxide; Depression, Chemical; | 1973 |
Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man.
Topics: Adult; Alcohol Drinking; Antipyrine; Coffee; Female; Genetics, Medical; Humans; Male; Metabolic Clea | 1969 |