phenobarbital has been researched along with Aggression in 30 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The goal of this study was to investigate the potential protective effects of nimodipine (ND), a calcium channel blocker, on the acute manifestations and long-term behavioral sequalae of experimental status epilepticus (SE)." | 7.72 | Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats. ( Bakkar, N; Carmant, L; Holmes, GL; Liu, Z; Mikati, MA; Stafstrom, CE; Werner, S, 2004) |
| "The goal of this study was to investigate the potential protective effects of nimodipine (ND), a calcium channel blocker, on the acute manifestations and long-term behavioral sequalae of experimental status epilepticus (SE)." | 3.72 | Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats. ( Bakkar, N; Carmant, L; Holmes, GL; Liu, Z; Mikati, MA; Stafstrom, CE; Werner, S, 2004) |
| "Rats in experiment 1 received 1% creatine or cyclocreatine chow from age (P) 21-65 days, underwent kainate induced status epilepticus on P35 and were compared, as adults, to kainate alone rats and to normal controls." | 3.72 | Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. ( Abu Rialy, S; Farhat, F; Francis, E; Geha, G; Kurdit, RM; Lteif, L; Maraashli, W; Mikati, MA; Rahmeh, AA, 2004) |
| "An adult female with developmental disability was prescribed chlorpromazine for the target behaviors of aggression and self-injurious behavior (SIB), and she was prescribed phenobarbital for seizures." | 3.68 | A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy. ( Hanzel, TE; Harder, SR; Kalachnik, JE, 1992) |
| "Sodium phenobarbitone (20 and 70 mg/kg) had a significant anticonvulsant action against pentylenetetrazole-induced seizures, which persisted for 21 days of treatment." | 3.68 | Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal. ( File, SE; Wilks, LJ, 1990) |
| " d-Amphetamine, cocaine, and caffeine each had the effect of elevating both bite and lever press responses; nicotine, chlorpromazine, chlordiazepoxide, and diazepam each elevated lever press responding while depressing bite responding across a portion of the dosage range; phenobarbital, alcohol, and morphine had the effect of depressing both bite and lever press responses but lever pressing was selectively more depressed than biting." | 1.27 | Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding. ( Emley, GS; Hutchinson, RR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (70.00) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BOURGAULT, PC | 1 |
| KARCZMAR, AG | 1 |
| SCUDDER, CL | 1 |
| WRIGHT, JA | 1 |
| Mikati, MA | 2 |
| Holmes, GL | 1 |
| Werner, S | 1 |
| Bakkar, N | 1 |
| Carmant, L | 1 |
| Liu, Z | 1 |
| Stafstrom, CE | 1 |
| Kurdit, RM | 1 |
| Rahmeh, AA | 1 |
| Farhat, F | 1 |
| Abu Rialy, S | 1 |
| Lteif, L | 1 |
| Francis, E | 1 |
| Geha, G | 1 |
| Maraashli, W | 1 |
| Dodman, NH | 3 |
| Billingham, EA | 1 |
| Moon-Fanelli, AA | 1 |
| Mizoule, J | 1 |
| Rataud, J | 1 |
| Uzan, A | 1 |
| Mazadier, M | 1 |
| Daniel, M | 1 |
| Gauthier, A | 1 |
| Ollat, C | 1 |
| Gueremy, C | 1 |
| Renault, C | 1 |
| Dubroeucq, MC | 1 |
| Emley, GS | 1 |
| Hutchinson, RR | 1 |
| Figler, MH | 1 |
| Klauenberg, BJ | 1 |
| Polc, P | 2 |
| Bonetti, EP | 1 |
| Pieri, L | 1 |
| Cumin, R | 1 |
| Angioi, RM | 1 |
| Möhler, H | 1 |
| Haefely, WE | 1 |
| Laurent, JP | 1 |
| Scherschlicht, R | 1 |
| Haefely, W | 1 |
| Bronson, R | 1 |
| Gliatto, J | 1 |
| Singh, Y | 1 |
| Jaiswal, AK | 1 |
| Singh, M | 1 |
| Bhattacharya, SK | 1 |
| Poindexter, AR | 1 |
| Thoa, NB | 2 |
| Tizabi, Y | 1 |
| Kopin, IJ | 2 |
| Maengwyn-Davies, GD | 2 |
| Zwirner, PP | 1 |
| Porsolt, RD | 1 |
| Loew, DM | 1 |
| Miczek, KA | 1 |
| Knowles, K | 1 |
| Thalhammer, JG | 1 |
| Shuster, L | 1 |
| Hanzel, TE | 1 |
| Kalachnik, JE | 1 |
| Harder, SR | 1 |
| File, SE | 1 |
| Wilks, LJ | 1 |
| Yen-Koo, HC | 1 |
| Tocus, EC | 1 |
| Balazs, T | 1 |
| Duckett, S | 1 |
| Cracco, J | 1 |
| Lublin, F | 1 |
| Scott, T | 1 |
| Johnson, DG | 1 |
| Weise, VK | 1 |
| Turlapaty, P | 1 |
| Shibata, S | 1 |
| Norton, TR | 1 |
| Kashiwagi, M | 1 |
| Kostowski, W | 1 |
| Holdsworth, L | 1 |
| Whitmore, K | 1 |
| Crowley, TJ | 1 |
| Puri, SK | 1 |
| Lal, H | 1 |
| Yamamoto, K | 1 |
| Sawada, T | 1 |
| Naito, Y | 1 |
| Kido, R | 1 |
| Robichaud, RC | 1 |
| Gylys, JA | 1 |
| Sledge, KL | 1 |
| Hillyard, IW | 1 |
| Descloux, A | 1 |
| Malcik, JB | 1 |
| Sofia, RD | 1 |
| Goldberg, ME | 1 |
30 other studies available for phenobarbital and Aggression
| Article | Year |
|---|---|
CONTRASTING BEHAVIORAL, PHARMACOLOGICAL, NEUROPHYSIOLOGICAL, AND BIOCHEMICAL PROFILES OF C57 B1/6 AND SC-I STRAINS OF MICE.
Topics: Adrenal Glands; Aggression; Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Mice; Neu | 1963 |
TRINURIDE IN THE TREATMENT OF MAJOR EPILEPSY.
Topics: Aggression; Anticonvulsants; Depression; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; Phenobarbit | 1965 |
Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats.
Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Calcium Channel Blockers; Drug Therapy, Comb | 2004 |
Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats.
Topics: Acute Disease; Aggression; Animals; Anticonvulsants; Creatine; Creatinine; Dietary Supplements; Emot | 2004 |
Animal behavior case of the month. Behavioral seizures.
Topics: Aggression; Analgesics, Opioid; Animals; Anticonvulsants; Behavior, Animal; Butorphanol; Cat Disease | 2005 |
Pharmacological evidence that PK 8165 behaves as a partial agonist of brain type benzodiazepine receptors.
Topics: Aggression; Animals; Anticonvulsants; Benzodiazepinones; Conflict, Psychological; Diazepam; Drinking | 1984 |
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditio | 1983 |
Pentobarbital sodium and attack behavior in male Siamese fighting fish.
Topics: Aggression; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fishes; Humans; Male; Pheno | 1980 |
Caffeine antagonizes several central effects of diazepam.
Topics: Aggression; Animals; Caffeine; Cats; Central Nervous System; Conflict, Psychological; Diazepam; Huma | 1981 |
Electrophysiological studies on the specific benzodiazepine antagonist Ro 15-1788.
Topics: Aggression; Animals; Benzodiazepines; Cats; Decerebrate State; Electroencephalography; Electrophysio | 1981 |
Tail chasing in a bull terrier.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dog Diseases; Dogs; Electroencephalography; Epileps | 1993 |
Effect of prenatal diazepam, phenobarbital, haloperidol and fluoxetine exposure on foot shock induced aggression in rats.
Topics: Aggression; Animals; Diazepam; Drug Evaluation, Preclinical; Electroshock; Female; Fluoxetine; Halop | 1998 |
Phenobarbital, propranolol, and aggression.
Topics: Aggression; Anti-Anxiety Agents; Anticonvulsants; Humans; Phenobarbital; Propranolol; Psychomotor Ag | 2000 |
Alterations of mouse adrenal medullary catecholamines and enzymes in response to attack: effect of pre- and post-treatment with phenobarbital.
Topics: Adrenal Medulla; Aggression; Animals; Epinephrine; Humans; Male; Mice; Mice, Inbred C57BL; Norepinep | 1976 |
Inter-group aggression in mice: a new method for testing the effects of centrally active drugs.
Topics: Aggression; Animals; Atropine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Humans; Imiprami | 1975 |
Phenobarbital-responsive episodic dyscontrol (rage) in dogs.
Topics: Aggression; Animals; Behavior, Animal; Dog Diseases; Dogs; Electroencephalography; Epilepsy, Tempora | 1992 |
A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy.
Topics: Adult; Aggression; Chlorpromazine; Diagnosis, Differential; Dose-Response Relationship, Drug; Epilep | 1992 |
Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal.
Topics: Aggression; Animals; Anticonvulsants; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Phen | 1990 |
The effects of chronic treatment and withdrawal of CNS depressants on aggressive behavior.
Topics: Aggression; Animals; Behavior, Animal; Chlordiazepoxide; Dose-Response Relationship, Drug; Dronabino | 1989 |
Electron microscopical diagnosis of lipidosis with the use of rectal biopsy.
Topics: Adolescent; Aggression; Biopsy; Chlorpromazine; Epilepsy; Gait; Humans; Inclusion Bodies; Intellectu | 1974 |
Influence of isolation and of fighting on adrenal tyrosine hydroxylase and phenylethanolamine-N-methyltransferase activities in three strains of mice.
Topics: Adrenal Medulla; Aggression; Animals; Behavior, Animal; Defense Mechanisms; Ethanolamines; Fear; Hum | 1973 |
A possible mechanism of action of a central stimulant substance isolated from the sea anemone Stoichactis kenti.
Topics: Adrenergic beta-Antagonists; Aggression; Amino Acids; Animals; Behavior, Animal; Chlorpromazine; Chr | 1973 |
A note on the effects of some psychotropic drugs on the aggressive behaviour in the ant, Formica rufa.
Topics: Aggression; Amphetamine; Animals; Ants; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Humans; | 1966 |
A study of children with epilepsy attending ordinary schools. I: their seizure patterns, progress and behaviour in school.
Topics: Adolescent; Aggression; Attention; Child; Child Behavior Disorders; Child, Preschool; Colitis, Ulcer | 1974 |
Dose-dependent facilitation or supression of rat fighting by methamphetamine, phenobarbital, or imipramine.
Topics: Aggression; Animals; Behavior, Animal; Depression, Chemical; Humans; Imipramine; Male; Methamphetami | 1972 |
Reduced threshold to pain induced aggression specifically related to morphine dependence.
Topics: Aggression; Animals; Dextroamphetamine; Drug Synergism; Electroshock; Ethanol; Humans; Male; Morphin | 1974 |
[Neuropharmacologic study on the effect of nitrazepam on the central nervous system].
Topics: Aggression; Amygdala; Animals; Appetitive Behavior; Behavior, Animal; Benzazepines; Brain; Cats; Cer | 1969 |
The pharmacology of prazepam. A new benzodiazepine derivative.
Topics: Aggression; Animals; Avoidance Learning; Behavior, Animal; Benzazepines; Cats; Chlordiazepoxide; Dia | 1970 |
[Treatment of the psychosyndrome of alcoholic withdrawal using Atrium].
Topics: Aggression; Alcoholism; Anxiety; Barbiturates; Depression; Drug Combinations; Drug Evaluation; Human | 1971 |
A comparative study of the effects of selected psychoactive agents upon three lesion-induced models of aggression in the rat.
Topics: Acridines; Aggression; Animals; Antidepressive Agents; Benzazepines; Chlordiazepoxide; Chlorpromazin | 1969 |