phenobarbital has been researched along with Age-Related Memory Disorders in 7 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin has shown antioxidant, anti-inflammatory and neuro-protective properties." | 1.36 | Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats. ( Gupta, YK; Mehla, J; Reeta, KH, 2010) |
| "In particular, memory deficits, attentional problems, psychomotor slowing and reading and writing difficulties are highlighted, and the impact of the seizures, brain damage, and anticonvulsant drugs on cognitive function noted." | 1.27 | [Cognitive effects of antiepileptic drugs]. ( Trimble, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reeta, KH | 1 |
| Mehla, J | 1 |
| Gupta, YK | 1 |
| Paul, V | 1 |
| Reddy, L | 1 |
| Ekambaram, P | 1 |
| Papatheodoropoulos, C | 1 |
| Sotiriou, E | 1 |
| Kotzadimitriou, D | 1 |
| Drimala, P | 1 |
| Mondadori, C | 1 |
| Schmutz, M | 1 |
| Baltzer, V | 1 |
| Wu, Y | 1 |
| Wang, L | 1 |
| Trimble, R | 1 |
7 other studies available for phenobarbital and Age-Related Memory Disorders
| Article | Year |
|---|---|
Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.
Topics: Animals; Anticonvulsants; Antioxidants; Avoidance Learning; Brain; Carbamazepine; Cognition Disorder | 2010 |
The effect of L-arginine on the memory impairing action of phenobarbitone in rats that convulsed after the injection of picrotoxin.
Topics: Animals; Arginine; Male; Memory Disorders; Nitric Oxide; Phenobarbital; Picrotoxin; Rats; Rats, Wist | 2004 |
At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes.
Topics: Action Potentials; Anesthetics, Intravenous; Animals; Anticonvulsants; Biological Clocks; Dose-Respo | 2007 |
Potentiation of the anticonvulsant effects of antiepileptic drugs by "nootropics"; a potential new therapeutic approach.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Synergis | 1984 |
The effects of antiepileptic drugs on spatial learning and hippocampal protein kinase C gamma in immature rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Carbamazepine; Hippocampus; Immunohistochemistry; Isoen | 2002 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; | 1987 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cogni | 1985 |