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phenobarbital and Adenocarcinoma, Basal Cell

phenobarbital has been researched along with Adenocarcinoma, Basal Cell in 17 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
" The influence of inhibitors and activators in vitro, the effect of enzyme preparation technic, aging, starvation, pretreatment with somatotropic hormone, phenobarbital or 3-methylcholanthrene, and the effect of a tumor were studied."3.66The effect of chemical and physiological factors on the kinetics for product formation as it relates to enzyme activity and concentration, reaction time and to substrate adsorption and affinity. ( Chrastil, J; Wilson, JT, 1982)
"Choline was not effective in inhibiting the development of lung metastases in either case."1.27Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats. ( Hoover, KL; Poirier, LA; Shivapurkar, N, 1986)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's5 (29.41)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schuetz, EG1
Beck, WT1
Schuetz, JD1
Fang, WF2
Strobel, HW2
Takahashi, M1
Kokubo, T1
Furukawa, F1
Kurokawa, Y1
Hayashi, Y1
Diwan, BA1
Rice, JM1
Ward, JM1
Ohshima, M1
Lynch, PH1
Koliada, AIu1
Gel'shteĭn, VI1
Kobliakov, VA1
Newaz, SN1
Chrastil, J1
Wilson, JT1
Pollard, M1
Luckert, PH1
Scheu, J1
Pescatore, P1
Hammel, P1
Durand, F1
Bertheau, P1
Bernuau, J1
Huc, D1
Gerbal, JL1
Degott, C1
Benhamou, JP1
Rosenberg, DW1
Leff, T1
Hukkanen, J1
Lassila, A1
Päivärinta, K1
Valanne, S1
Sarpo, S1
Hakkola, J1
Pelkonen, O1
Raunio, H1
Feuer, G1
Kellen, JA1
Kovacs, K1
Bibby, MC1
Phillips, RM1
Double, JA1
Chabot, GG1
Bissery, MC1
Gouyette, A1
Shivapurkar, N1
Hoover, KL1
Poirier, LA1
Cooper, TP1
Barham, RE1
Ansell, JS1
Hendricks, GL1
Barnes, WT1
Hood, HL1

Other Studies

17 other studies available for phenobarbital and Adenocarcinoma, Basal Cell

ArticleYear
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:2

    Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, No

1996
Effects of cyclophosphamide and polycyclic aromatic hydrocarbons on cell growth and mixed-function oxidase activity in a human colon tumor cell line.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Adenocarcinoma; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Ce

1982
Effects of sodium chloride, saccharin, phenobarbital and aspirin on gastric carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.
    Gan, 1984, Volume: 75, Issue:6

    Topics: Adenocarcinoma; Animals; Aspirin; Carcinogens; Male; Methylnitronitrosoguanidine; Phenobarbital; Rat

1984
Inhibition by phenobarbital and lack of effect of amobarbital on the development of liver tumors induced by N-nitrosodiethylamine in juvenile B6C3F1 mice.
    Cancer letters, 1984, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Adenoma; Amobarbital; Animals; Body Weight; Diethylnitrosamine; Liver Neoplasms, Exp

1984
[Localization of cytochrome P-450PB in the rat liver and primary liver tumors of different histological structure after administration of inductor aroclor 1254].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:10

    Topics: Adenocarcinoma; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Di

1982
Metabolism of the carcinogen 1,2-dimethylhydrazine by isolated human colon microsomes and human colon tumor cells in culture.
    Cancer, 1983, Sep-01, Volume: 52, Issue:5

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adult; Biotransformation; Carcinogens; Cells, Cultured; Colon

1983
The effect of chemical and physiological factors on the kinetics for product formation as it relates to enzyme activity and concentration, reaction time and to substrate adsorption and affinity.
    The International journal of biochemistry, 1982, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Animals; Ascorbic Acid Deficiency; Enzyme Activation; Enzyme Inhibitors; Enzymes; Fe

1982
Phenobarbital promotes the development of adenocarcinomas in the accessory sex glands of MNU-inoculated L-W rats.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Abdominal Neoplasms; Adenocarcinoma; Adenoma; Aging; Animals; Carcinogens; Drug Implants; Genital Ne

1995
[Fatal fulminant hepatitis induced by nilutamide (Anandron)].
    Gastroenterologie clinique et biologique, 1993, Volume: 17, Issue:6-7

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Drug Interaction

1993
Regulation of cytochrome P450 in cultured human colonic cells.
    Archives of biochemistry and biophysics, 1993, Volume: 300, Issue:1

    Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinoma

1993
Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Anti-Inflammatory Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cy

2000
Is there any association between elevated serum prolactin level and mammary adenocarcinoma induced by 7,12-dimethylbenz(alpha)anthracene.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 11, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Coumarins; Female; Li

1975
The relationship between tissue levels of flavone acetic acid (NSC 347512) and site dependent anti-tumour activity in murine colon tumours.
    British journal of cancer, 1991, Volume: 63, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biological Availability; Colonic Neoplasms; Drug Scr

1991
Flavone acetic acid (LM-975; NSC-347512) activation to cytotoxic species in vivo and in vitro.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cells, Cultured; Colonic Neoplasms; Dose-Response Re

1989
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung N

1986
Methylcholanthrene-induced adenocarcinoma of the prostate in rats.
    Surgical forum, 1974, Volume: 25, Issue:0

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasms, Experimental

1974
Seven-year "cure" of lung cancer with metastasis to the brain.
    JAMA, 1972, Apr-03, Volume: 220, Issue:1

    Topics: Adenocarcinoma; Brain Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Phe

1972