phenobarbital has been researched along with Acute Lymphoid Leukemia in 1 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A possible pharmacokinetic interaction between teniposide and anticonvulsant medications was evaluated in pediatric patients." | 1.28 | Increased teniposide clearance with concomitant anticonvulsant therapy. ( Baker, DK; Christensen, ML; Evans, WE; Pui, CH; Relling, MV; Rodman, JH, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, DK | 1 |
| Relling, MV | 1 |
| Pui, CH | 1 |
| Christensen, ML | 1 |
| Evans, WE | 1 |
| Rodman, JH | 1 |
1 other study available for phenobarbital and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Increased teniposide clearance with concomitant anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Int | 1992 |