Page last updated: 2024-11-02

phenobarbital and Acidosis

phenobarbital has been researched along with Acidosis in 15 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
" In this study cerebral blood flow values in steady state and during phenylephrine-induced hypertension with and without phenobarbital pretreatment were measured in newborn beagles."7.68Phenobarbital and cerebral blood flow during hypertension in the newborn beagle. ( Adham, BI; Donley, DK; Goddard-Finegold, J; Michael, LH, 1990)
"Strychnine poisoning results in a predictable and treatable sequence of events involving blockade of the inhibitory neurotransmitter, extensor muscle spasms, seizures, and respiratory paralysis."7.66Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis. ( Boyd, RE; Brennan, PT; Deng, JF; Rochester, DF; Spyker, DA, 1983)
" In this study cerebral blood flow values in steady state and during phenylephrine-induced hypertension with and without phenobarbital pretreatment were measured in newborn beagles."3.68Phenobarbital and cerebral blood flow during hypertension in the newborn beagle. ( Adham, BI; Donley, DK; Goddard-Finegold, J; Michael, LH, 1990)
"Clinical and experimental studies were performed on the mechanisms of metabolic acidosis observed in the children with epilepsy who had long been treated with anticonvulsants such as phenobarbital (PB) or diphenylhydantoin (DPH)."3.66[Studies on the mechanism of metabolic acidosis observed in the children treated with anticonvulsants]. ( Nagai, B, 1982)
"Strychnine poisoning results in a predictable and treatable sequence of events involving blockade of the inhibitory neurotransmitter, extensor muscle spasms, seizures, and respiratory paralysis."3.66Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis. ( Boyd, RE; Brennan, PT; Deng, JF; Rochester, DF; Spyker, DA, 1983)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199011 (73.33)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fenves, AZ1
Mojtahed, A1
Nisavic, M1
Massoth, LR1
WONG, LC1
HEIMBACH, MD1
TRUSCOTT, DR1
DUNCAN, BD1
DUNDAS, JB1
Hori, Y1
Fujisawa, M1
Shimada, K1
Hirose, Y1
Yoshioka, T1
Bukowskyj, M1
Nakatsu, K1
Munt, PW1
Bock, JL1
Nagai, B1
Boyd, RE1
Brennan, PT1
Deng, JF1
Rochester, DF1
Spyker, DA1
Tenenbein, M1
Casiro, OG1
Seshia, MM1
Debooy, VD1
Borison, HL1
Snow, SR1
Longnecker, DS1
Smith, RP1
Goddard-Finegold, J1
Donley, DK1
Adham, BI1
Michael, LH1
Greisen, G1
Frederiksen, PS1
Hertel, J1
Christensen, NJ1
Thaler, MM1
Behrman, RE1
Fisher, D1
Paton, JB1
Keller, J1
Gladtke, E1

Reviews

2 reviews available for phenobarbital and Acidosis

ArticleYear
Theophylline reassessed.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents;

1984
In utero disease and the newborn infant.
    Advances in pediatrics, 1970, Volume: 17

    Topics: Acid-Base Equilibrium; Acidosis; Amniotic Fluid; Animals; Bilirubin; Birth Weight; Electrocardiograp

1970

Other Studies

13 other studies available for phenobarbital and Acidosis

ArticleYear
Case 13-2019: A 54-Year-Old Man with Alcohol Withdrawal and Altered Mental Status.
    The New England journal of medicine, 2019, Apr-25, Volume: 380, Issue:17

    Topics: 2-Propanol; Acetone; Acid-Base Equilibrium; Acidosis; Alcohol Withdrawal Delirium; Alcoholism; Diagn

2019
BORIC ACID POISONING: REPORT OF 11 CASES.
    Canadian Medical Association journal, 1964, Apr-25, Volume: 90

    Topics: Acidosis; Anti-Bacterial Agents; Borates; Boric Acids; Color Perception Tests; Dehydration; Diarrhea

1964
LOWE'S SYNDROME.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Acidosis; Albuminuria; Alkalies; Anti-Bacterial Agents; Blood; Bone Diseases; Calcium; Cataract; Chi

1964
Method for screening and quantitative determination of serum levels of salicylic Acid, acetaminophen, theophylline, phenobarbital, bromvalerylurea, pentobarbital, and amobarbital using liquid chromatography/electrospray mass spectrometry.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:1

    Topics: Acetaminophen; Acidosis; Adult; Amobarbital; Analgesics, Non-Narcotic; Bromisovalum; Calibration; Ch

2006
Analysis of serum by high-field proton nuclear magnetic resonance.
    Clinical chemistry, 1982, Volume: 28, Issue:9

    Topics: Acidosis; Adult; Aged; Blood Chemical Analysis; Blood Glucose; Diabetic Ketoacidosis; Ethanol; Human

1982
[Studies on the mechanism of metabolic acidosis observed in the children treated with anticonvulsants].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1982, Volume: 57, Issue:6

    Topics: Acidosis; Adolescent; Binding Sites; Calcium; Carbonic Anhydrases; Child; Child, Preschool; Drug The

1982
Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Topics: Acidosis; Adult; Body Temperature; Creatine Kinase; Female; Fever; Glycine; Humans; Hydrogen-Ion Con

1983
Neonatal withdrawal from maternal volatile substance abuse.
    Archives of disease in childhood. Fetal and neonatal edition, 1996, Volume: 74, Issue:3

    Topics: Acidosis; Cohort Studies; Female; GABA Modulators; Humans; Infant, Newborn; Male; Neonatal Abstinenc

1996
3-Chloro-p-toluidine: effects of lethal doses in rats and cats.
    Toxicology and applied pharmacology, 1975, Volume: 31, Issue:3

    Topics: Acidosis; Animals; Blood Pressure; Carbon Dioxide; Cats; In Vitro Techniques; Male; Oxygen Consumpti

1975
Phenobarbital and cerebral blood flow during hypertension in the newborn beagle.
    Pediatrics, 1990, Volume: 86, Issue:4

    Topics: Acidosis; Animals; Animals, Newborn; Cerebral Hemorrhage; Cerebrovascular Circulation; Dogs; Hemodyn

1990
Catecholamine response to chest physiotherapy and endotracheal suctioning in preterm infants.
    Acta paediatrica Scandinavica, 1985, Volume: 74, Issue:4

    Topics: Acidosis; Blood Pressure; Cerebral Hemorrhage; Epinephrine; Humans; Infant Care; Infant, Newborn; In

1985
Neonatal hyperbilirubinemia.
    Seminars in hematology, 1972, Volume: 9, Issue:2

    Topics: Acidosis; Agar; Anemia, Hemolytic; Antibodies; Bilirubin; Blood Group Incompatibility; Blood Transfu

1972
[Acetonemic vomiting].
    Monatsschrift fur Kinderheilkunde, 1969, Volume: 117, Issue:11

    Topics: Abdomen, Acute; Acidosis; Brain Neoplasms; Child, Preschool; Diabetic Coma; Diagnosis, Differential;

1969