phenobarbital has been researched along with Abnormalities, Congenital in 14 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| ", raise the possibility that fetal damage previously attributed to phenytoin and other anticonvulsant drugs, principally phenobarbitone, may be due to epilepsy itself." | 3.65 | Anticonvulsants and parental epilepsy in the development of birth defects. ( Hartz, SC; Heinonen, OP; Mitchell, AA; Monson, RR; Rosenberg, L; Shapiro, S; Siskind, V; Slone, D, 1976) |
| "Seizures and intracranial hemorrhage are possible medical diseases that any obstetrician may encounter." | 2.49 | Seizures and intracranial hemorrhage. ( Alexander, JM; Wilson, KL, 2013) |
| "Heroin exposure was accomplished by injecting dams during the same gestational period." | 1.29 | Neural grafting as a tool for the study and reversal of neurobehavioral birth defects. ( Abu-Roumi, M; Silverman, WF; Steingart, RA; Yanai, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilson, KL | 1 |
| Alexander, JM | 1 |
| Barroso, FV | 1 |
| Araujo Júnior, E | 1 |
| Guazelli, CA | 1 |
| Santana, EF | 1 |
| Rolo, LC | 1 |
| Martins, Mda G | 1 |
| Moron, AF | 1 |
| Abdel-Latif, ME | 1 |
| Oei, J | 1 |
| Craig, F | 1 |
| Lui, K | 1 |
| Hiilesmaa, VK | 1 |
| Teramo, K | 1 |
| Granström, ML | 1 |
| Bardy, AH | 1 |
| Yanai, J | 1 |
| Abu-Roumi, M | 1 |
| Silverman, WF | 1 |
| Steingart, RA | 1 |
| Holmes, LB | 1 |
| Harvey, EA | 1 |
| Coull, BA | 1 |
| Huntington, KB | 1 |
| Khoshbin, S | 1 |
| Hayes, AM | 1 |
| Ryan, LM | 1 |
| Shapiro, S | 1 |
| Hartz, SC | 1 |
| Siskind, V | 1 |
| Mitchell, AA | 1 |
| Slone, D | 1 |
| Rosenberg, L | 1 |
| Monson, RR | 1 |
| Heinonen, OP | 1 |
| Lowe, CR | 1 |
| Annegers, JF | 1 |
| Elveback, LR | 1 |
| Hauser, WA | 1 |
| Kurland, LT | 1 |
| Fitz, CR | 1 |
| Harwood-Nash, DC | 1 |
| Volpe, J | 1 |
| Fedrick, J | 1 |
| Monod, N | 1 |
| Dreyfus-Brisac, C | 1 |
| Sfaello, Z | 1 |
| Dean, D | 1 |
2 reviews available for phenobarbital and Abnormalities, Congenital
| Article | Year |
|---|---|
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; H | 2013 |
Neonatal Seizures.
Topics: Birth Injuries; Calcium; Congenital Abnormalities; Glucose; Humans; Hypocalcemia; Hypoglycemia; Infa | 1973 |
12 other studies available for phenobarbital and Abnormalities, Congenital
| Article | Year |
|---|---|
Perinatal outcomes from the use of antiepileptic drugs during pregnancy: a case-control study.
Topics: Adult; Anticonvulsants; Apgar Score; Case-Control Studies; Congenital Abnormalities; Epilepsy; Femal | 2015 |
Profile of infants born to drug-using mothers: a state-wide audit.
Topics: Australian Capital Territory; Breast Feeding; Congenital Abnormalities; Female; Hospitalization; Hos | 2013 |
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobar | 1983 |
Neural grafting as a tool for the study and reversal of neurobehavioral birth defects.
Topics: Animals; Behavior, Animal; Brain Tissue Transplantation; Cell Transplantation; Congenital Abnormalit | 1996 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnorm | 2001 |
Anticonvulsants and parental epilepsy in the development of birth defects.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Epilepsy; Female; Finland; Follow-Up Studies; | 1976 |
Congenital malformations among infants born to epileptic women.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; F | 1973 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital | 1974 |
Radiology of the ear in children.
Topics: Child; Child, Preschool; Chlorpromazine; Cholesteatoma; Cochlea; Congenital Abnormalities; Ear; Ear | 1974 |
Epilepsy and pregnancy: a report from the Oxford Record Linkage Study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Child; Congenital Abnormalities; Drug S | 1973 |
[Detection and prognosis of the neonatal mal according to the electroclinical study of 150 cases].
Topics: Cerebral Hemorrhage; Cerebrovascular Disorders; Congenital Abnormalities; Electroencephalography; Ep | 1969 |
[Results of treatment of hypertrophic pyloric stenosis in 351 infants from 1945-1964].
Topics: Age Factors; Atropine; Birth Weight; Congenital Abnormalities; Diagnosis, Differential; Diet Therapy | 1970 |