phenoaldehyde and Dental-Pulp-Diseases

The principles, indications, and techniques of resinifying therapy and the composition of a resinifying agent are described in this article. The permeability and bacteriostasis of the agent and the volume change of the agent after treatment were observed, and 14C-labeled phenoaldehyde showed that the agent not only filled the main canals and accessory canals but also infiltrated into dentinal tubules with a depth one fourth to one third the total length of the tubules. The antimicrobial activity of the agent after polymerization for 2 to 6 months was determined. Even 9 months after treatment, no change in volume of the agent was found in vivo, and sealing of canals was maintained. Seventy-eight teeth in 69 patients with pulpoperiapical diseases were subjected to resinifying therapy and followed up for 6 to 12 months; the success rate was 82.05%. The histologic study indicated that, of the specimens experimentally treated for 6 to 12 months, 85.7% showed mild or no inflammation while 53.6% showed complete healing or an obvious healing tendency. Furthermore, the mechanisms and advantages of this therapy are discussed.

Topics: Animals; Bacteria; Cresols; Dental Pulp Diseases; Dogs; Drug Combinations; Follow-Up Studies; Formaldehyde; Humans; Indicators and Reagents; Resins, Synthetic; Resorcinols; Root Canal Filling Materials; Root Canal Therapy; Tooth Permeability; Tooth Root