Page last updated: 2024-11-02

phenindione and Thrombosis

phenindione has been researched along with Thrombosis in 55 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
" We studied the antithrombotic efficacy of the vitamin K antagonist fluindione in a human ex vivo model of arterial thrombosis and determined whether aspirin enhances fluindione efficacy."9.09Antithrombotic efficacy of the vitamin K antagonist fluindione in a human Ex vivo model of arterial thrombosis : effect of anticoagulation level and combination therapy with aspirin. ( Boneu, B; Bossavy, JP; Cadroy, Y; Sakariassen, KS; Thalamas, C, 1999)
"Thirty-one consecutive patients with deep vein thrombosis were treated with Fraxiparine, a low molecular weight heparin, and fluindione, an oral anticoagulant prescribed at an early stage."9.07[Treatment of venous thrombosis with low molecular weight heparin and fluindione]. ( Aiach, M; Alhenc-Gelas, M; Fiessinger, JN; Martin, JB; Paul, JF; Veyssier, C, 1992)
"Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation."7.71Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002)
" We studied the antithrombotic efficacy of the vitamin K antagonist fluindione in a human ex vivo model of arterial thrombosis and determined whether aspirin enhances fluindione efficacy."5.09Antithrombotic efficacy of the vitamin K antagonist fluindione in a human Ex vivo model of arterial thrombosis : effect of anticoagulation level and combination therapy with aspirin. ( Boneu, B; Bossavy, JP; Cadroy, Y; Sakariassen, KS; Thalamas, C, 1999)
"Thirty-one consecutive patients with deep vein thrombosis were treated with Fraxiparine, a low molecular weight heparin, and fluindione, an oral anticoagulant prescribed at an early stage."5.07[Treatment of venous thrombosis with low molecular weight heparin and fluindione]. ( Aiach, M; Alhenc-Gelas, M; Fiessinger, JN; Martin, JB; Paul, JF; Veyssier, C, 1992)
"Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation."3.71Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002)
"This is the first study to propose a conversion algorithm to help prescribers to estimate the maintenance dosage when it is necessary for a patient to switch from fluindione to warfarin or conversely."2.80[Relationship between maintenance dosages of fluindione (Préviscan) and warfarin (Coumadin) for patients 70 years and older]. ( Badie, C; Bouhadiba, S; Golmard, JL; Gouin-Thibault, I; Gouronnec, A; Monti, A; Pautas, É; Peyron, I; Siguret, V, 2015)
"An aortic valve thrombus (AVT) is a rare complication after HeartMate II implantation."1.46Exercise Training in a Patient With a Left Ventricular Assist Device and Large Aortic Valve Thrombus. ( Ben Elhaj, H; Damy, T; Deux, JF; Gellen, B; Guendouz, S; Lellouche, N; Peyrot, S; Radu, C; Wuliya, M, 2017)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199044 (80.00)18.7374
1990's2 (3.64)18.2507
2000's4 (7.27)29.6817
2010's5 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wuliya, M1
Peyrot, S1
Radu, C1
Deux, JF1
Ben Elhaj, H1
Lellouche, N1
Damy, T1
Guendouz, S1
Gellen, B1
Kamaliddin, C1
Joste, V1
Argy, N1
Houzé, S1
Pautas, É1
Peyron, I1
Gouin-Thibault, I1
Gouronnec, A1
Monti, A1
Bouhadiba, S1
Badie, C1
Golmard, JL1
Siguret, V1
Béné, J1
Dubart, AE1
Senis, C1
Auffret, M1
Caron, J1
Gautier, S1
Gaertner, S1
Cordeanu, EM1
Mirea, C1
Stephan, D1
Kachalova, ND1
Klimovich, LG1
Berkovskiĭ, AL1
Prostakova, TM1
Kozlov, AA1
Royer, B1
Ziegler, F1
Muret, P1
Davani, S1
Kantelip, JP1
Boneu, B2
Léger, P1
Meurin, P1
Renaud, N1
Weber, H1
Tabet, JY1
Grosdemouge, A1
Bourmayan, C1
Ben Driss, A1
TOOHEY, M1
MARKS, J1
TRUSCOTT, BM1
WITHYCOMBE, JF1
MALAGOLI, F1
STURA, L1
CRAVAREZZA, F1
DUFF, IF1
GAMBLE, JR1
WILLIS, PW1
HODGSON, PE1
WILSON, WS1
POLHEMUS, JA1
HAASE, HW1
BUSCHER, G1
SCORCIARINI-COPPOLA, A1
KELLAWAY, G1
BUZZI, A1
CARBAJAL, B1
DUTHIE, HL1
SMITH, G1
DAVIDSON, E1
HOWARD, AN1
GRESHAM, GA1
GORMSEN, J1
SHIMAMOTO, T1
ISHIOKA, T1
FUJITA, T1
GRONROOS, M1
HAKULINEN, A1
KIVIKOSKI, A1
SEVITT, S3
INNES, D1
GIBELLI, A1
DELUTTEROTTI, A1
WELTI, JJ1
BEINSTEIN, J1
LANDER, H1
KINLOUGH, RL1
ROBSON, HN1
CUNNINGHAM, GM1
MCNICOL, GP1
DOUGLAS, AS2
BLAUSTEIN, AU1
CROCE, JJ1
ALBERIAN, M1
RICHEY, N1
Lawson, DH1
McDonald, GA1
Bossavy, JP1
Sakariassen, KS1
Thalamas, C1
Cadroy, Y1
Fiessinger, JN1
Paul, JF1
Alhenc-Gelas, M1
Veyssier, C1
Martin, JB1
Aiach, M1
Rado, Iu1
Chikvashvili, DI1
Guagliano, G1
Borri, P1
Colombo, P1
Vittori, C1
McIntyre, H1
Kincaid-Smith, P2
Larcan, A1
Bertrand, P1
Richon, J1
Calamai, M1
Straub, PW1
Browse, NL1
Forbes, CD1
Prentice, CR1
Jouve, A1
Pierron, J1
Avril, P1
Nakache, A1
Hunt, PS1
Reeve, TS1
Hollings, RM1
Fiedler, H1
Thiele, G1
Josso, F1
Cosson, A1
Papadimitriou, M1
Carroll, RN1
Kulatilake, AE1
Lechner, K1
Uglov, FG1
Zubtsovskiĭ, VN1
Pup, GP1
Kalenik, LI1
Marchal, G1
Domart, A1
Bilski-Pasquier, G1
Abastado, M1
Goglin, G1
Samama, M1
Marx, R1
Hutton, I1
Reid, DS1
Linton, AL1

Reviews

3 reviews available for phenindione and Thrombosis

ArticleYear
[Oral anticoagulant treatment: practical aspects and significance of anticoagulant clinics].
    Annales de cardiologie et d'angeiologie, 2002, Volume: 51, Issue:3

    Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Drug Interactions; Family Practice; Food; Hemor

2002
[Indications for and hazards of anticoagulant therapy].
    Schweizerische medizinische Wochenschrift, 1970, Apr-18, Volume: 100, Issue:16

    Topics: Anticoagulants; Cerebrovascular Disorders; Coumarins; Diabetic Angiopathies; Disseminated Intravascu

1970
Anticoagulants.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Anticoagulants; Aspirin; Blood Platelet Disorders; Dipyridamole; Enzyme Therapy; Factor IX; Factor V

1974

Trials

5 trials available for phenindione and Thrombosis

ArticleYear
[Relationship between maintenance dosages of fluindione (Préviscan) and warfarin (Coumadin) for patients 70 years and older].
    La Revue de medecine interne, 2015, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Algorithms; Anticoagulants; Dose-Response Relationship, Drug; Drug D

2015
[Treatment of left intraventricular thrombosis with low molecular weight heparin].
    Archives des maladies du coeur et des vaisseaux, 2003, Volume: 96, Issue:4

    Topics: Aged; Anticoagulants; Echocardiography; Enoxaparin; Feasibility Studies; Female; Heparin, Low-Molecu

2003
Antithrombotic efficacy of the vitamin K antagonist fluindione in a human Ex vivo model of arterial thrombosis : effect of anticoagulation level and combination therapy with aspirin.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Collagen; Drug Synergism; Drug Therapy, Combination; Fib

1999
[Treatment of venous thrombosis with low molecular weight heparin and fluindione].
    Presse medicale (Paris, France : 1983), 1992, Jan-18, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Drug Therapy, Combination; Heparin, Low-Molecular-We

1992
Management, during dental surgery, of patients on anticoagulants.
    Lancet (London, England), 1966, Jul-09, Volume: 2, Issue:7454

    Topics: Acenocoumarol; Anti-Bacterial Agents; Blood Coagulation Tests; Clinical Trials as Topic; Coronary Di

1966

Other Studies

47 other studies available for phenindione and Thrombosis

ArticleYear
Exercise Training in a Patient With a Left Ventricular Assist Device and Large Aortic Valve Thrombus.
    Journal of cardiopulmonary rehabilitation and prevention, 2017, Volume: 37, Issue:6

    Topics: Adult; Anticoagulants; Aortic Valve; Cardiac Rehabilitation; Exercise Therapy; Heart-Assist Devices;

2017
[Fluindione and falciparum malaria treated by atovaquone-proguanil].
    Therapie, 2018, Volume: 73, Issue:5

    Topics: Anticoagulants; Antimalarials; Atovaquone; Drug Combinations; Drug Interactions; Female; Heart Valve

2018
Risk factors associated with a thrombotic or bleeding event in patients treated with vitamin K antagonists.
    Journal des maladies vasculaires, 2014, Volume: 39, Issue:4

    Topics: Acenocoumarol; Aged; Aged, 80 and over; Anticoagulants; Case-Control Studies; Drug Interactions; Eme

2014
Prothrombotic risk of vitamin K antagonists during the first days of treatment: One more reason to use new oral anticoagulants.
    International journal of cardiology, 2015, Volume: 186

    Topics: Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Electrocardiography; Factor Xa Inhibitors; F

2015
[Use of domestic thromboplastins with attested international indices of sensitivity in the treatment of thrombophilia].
    Klinicheskaia laboratornaia diagnostika, 2002, Issue:6

    Topics: Administration, Oral; Animals; Anticoagulants; Humans; International Normalized Ratio; Phenindione;

2002
Acitretin-associated thrombotic stroke.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:12

    Topics: Acitretin; Analgesics; Anticoagulants; Antiemetics; Dextropropoxyphene; Domperidone; Female; Headach

2002
Clinical trial of phenylindanedione as an anticoagulant.
    British medical journal, 1953, Mar-21, Volume: 1, Issue:4811

    Topics: Anticoagulants; Phenindione; Thrombosis

1953
Treatment of venous thrombosis with anticoagulants; review of 1135 cases.
    Lancet (London, England), 1954, Oct-16, Volume: 267, Issue:6842

    Topics: Anticoagulants; Coumarins; Heparin; Humans; Phenindione; Pulmonary Embolism; Thrombosis; Venous Thro

1954
[Phenylindanedione anticoagulant therapy in obstetrics and gynecology].
    Annali di ostetricia e ginecologia, 1955, Volume: 77, Issue:4

    Topics: Anticoagulants; Female; Gynecology; Humans; Obstetrics; Phenindione; Postpartum Period; Thrombosis

1955
[Anticoagulant and hemostatic therapy in obstetrics and gynecology. I. Phenylindanedione].
    Quaderni di clinica ostetrica e ginecologica, 1955, Volume: 10, Issue:7

    Topics: Anticoagulants; Blood Coagulation; Female; Genital Diseases, Female; Gynecology; Hemostatics; Humans

1955
The control of excessive effect by anticoagulants.
    Annals of internal medicine, 1955, Volume: 43, Issue:5

    Topics: Anticoagulants; Coumarins; Hemostatics; Humans; Phenindione; Protamines; Thrombosis; Vitamin K

1955
[Treatment of thrombosis with 2-phenylinandion].
    Zentralblatt fur Chirurgie, 1955, Volume: 80, Issue:31

    Topics: Humans; Phenindione; Thromboembolism; Thrombosis

1955
[Thrombotic glaucoma during anticoagulant therapy].
    Annali di ottalmologia e clinica oculistica, 1958, Volume: 84, Issue:1

    Topics: Anticoagulants; Glaucoma; Hypertension; Medical Records; Phenindione; Thrombosis

1958
Clinical evaluation of miradon.
    British medical journal, 1958, Oct-11, Volume: 2, Issue:5101

    Topics: Coronary Disease; Humans; Myocardial Infarction; Phenindione; Thrombosis

1958
[Clinical evaluation of the anticoagulant, phenylindanedione].
    Medicina panamericana, 1958, Volume: 11, Issue:9-10

    Topics: Anticoagulants; Arteriosclerosis Obliterans; Coronary Disease; Humans; Phenindione; Pulmonary Emboli

1958
Failure of phenindione to prevent intravascular clotting.
    Scottish medical journal, 1960, Volume: 5

    Topics: Anticoagulants; Humans; Myocardial Infarction; Phenindione; Thrombosis

1960
The effect of phenindione on rats fed diets which produce thrombosis or experimental atherosclerosis.
    British journal of experimental pathology, 1962, Volume: 43

    Topics: Animals; Arteriosclerosis; Atherosclerosis; Diet; Phenindione; Rats; Thrombosis

1962
Thrombelastography and hypercoagulability.
    Acta medica Scandinavica, 1961, Volume: 170

    Topics: Phenindione; Thrombelastography; Thrombophilia; Thrombosis

1961
Antithrombotic effect of monamine oxidase inhibitor (nialamide).
    Circulation research, 1962, Volume: 10

    Topics: Coumarins; Humans; Monoamine Oxidase Inhibitors; Nialamide; Oxidoreductases; Phenindione; Thrombosis

1962
Does phenylindandione administered to the mother involve a risk for the nursing infant?
    Annales paediatriae Fenniae, 1962, Volume: 8

    Topics: Breast Feeding; Female; Humans; Mothers; Phenindione; Puerperal Disorders; Risk; Thrombosis

1962
EVIDENCE AGAINST "REBOUND" THROMBOSIS AFTER STOPPING ORAL ANTICOAGULANT DRUGS.
    Lancet (London, England), 1963, Nov-09, Volume: 2, Issue:7315

    Topics: Anticoagulants; Coronary Disease; Humans; Phenindione; Thrombophlebitis; Thrombosis

1963
[RESEARCH ON THE ANTICOAGULANT ACTION OF AN INDANDIONE DERIVATIVE (ANISINDIONE) WITH PROLONGED ACTION].
    Rassegna internazionale di clinica e terapia, 1964, Jan-15, Volume: 44

    Topics: Anticoagulants; Biomedical Research; Blood Coagulation Tests; Delayed-Action Preparations; Humans; P

1964
[ANTICOAGULANT TREATMENT].
    Les Cahiers du College de medecine des hopitaux de Paris, 1964, Volume: 5

    Topics: Anticoagulants; Blood Coagulation Tests; Ethyl Biscoumacetate; Heparin; Humans; Phenindione; Thrombo

1964
OUTPATIENT ANTICOAGULATION: A PROBLEM IN LONG-TERM MANAGEMENT.
    Virginia medical monthly, 1964, Volume: 91

    Topics: Blood Coagulation Tests; Coronary Disease; Dicumarol; Geriatrics; Intracranial Embolism; Intracrania

1964
REDUCED PLATELET SURVIVAL IN PATIENTS WITH STARR-EDWARDS PROSTHESES.
    British medical journal, 1965, Mar-13, Volume: 1, Issue:5436

    Topics: Blood Platelet Disorders; Blood Platelets; Chromium Isotopes; Citrates; Drug Therapy; Embolism; Gluc

1965
EFFECT OF ANTICOAGULANT DRUGS ON PLATELET AGGREGATION IN THE CHANDLER'S TUBE.
    Lancet (London, England), 1965, Apr-03, Volume: 1, Issue:7388

    Topics: Anticoagulants; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Drug Therapy; Heparin;

1965
Preliminary report on the clinical use of a new anticoagulant, phenylindandione.
    Circulation, 1950, Volume: 1, Issue:5

    Topics: Anticoagulants; Phenindione; Thrombosis

1950
Control of long-term anticoagulant therapy.
    Scottish medical journal, 1967, Volume: 12, Issue:4

    Topics: Anticoagulants; Embolism; Humans; Hypertension, Pulmonary; Myocardial Infarction; Phenindione; Renal

1967
[Effect of long-term anticoagulant and antithrombocytic therapy on the size of intracavitary thrombus and the incidence of thromboembolic complications in patients with acute myocardial infarction].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1989, Volume: 12, Issue:1

    Topics: Aspirin; Heart Diseases; Humans; Myocardial Infarction; Phenindione; Thromboembolism; Thrombosis; Ti

1989
[Direct surgery of the arteries (synthetic prosthesis and prevention of secondary thrombosis)].
    Minerva chirurgica, 1970, Jul-15, Volume: 25, Issue:13

    Topics: Aneurysm; Animals; Aortic Aneurysm; Aortography; Arteries; Arteriosclerosis; Arteriosclerosis Oblite

1970
Modification of the vascular lesions of rejection in cadaveric renal allografts by dipyridamole and anticoagulants.
    Lancet (London, England), 1969, Nov-01, Volume: 2, Issue:7627

    Topics: Anticoagulants; Cadaver; Dipyridamole; Graft vs Host Reaction; Heparin; Humans; Kidney; Kidney Glome

1969
[Necrotic and bullous skin complications of anti-vitamin K].
    La Presse medicale, 1968, May-22, Volume: 76, Issue:25

    Topics: Adult; Aged; Drug Eruptions; Ethyl Biscoumacetate; Female; Humans; Male; Necrosis; Phenindione; Post

1968
The pathogenesis of the vascular and glomerular lesions of rejection in renal allografts and their modification by antithromtotic and anticoagulant drugs.
    Australasian annals of medicine, 1970, Volume: 19, Issue:3

    Topics: Blood Vessels; Dipyridamole; Graft vs Host Reaction; Heparin; Humans; Kidney; Kidney Transplantation

1970
Blood and neoplastic diseases. Thrombosis: treatment and prophylaxis.
    British medical journal, 1974, Oct-12, Volume: 4, Issue:5936

    Topics: Anticoagulants; Blood Coagulation; Catheterization; Clot Retraction; Electric Stimulation; Embolism;

1974
[Arterial diseases of the lower limbs. Treatment with anticoagulants. Value of their long-term use].
    La Nouvelle presse medicale, 1972, Sep-30, Volume: 1, Issue:34

    Topics: Adult; Aged; Anticoagulants; Arteries; Arteriosclerosis; Coronary Disease; Ethyl Biscoumacetate; Fem

1972
A comparison of the anticoagulant effects of heparin and phenindione on a standard experimental arterial thrombus.
    The Australian and New Zealand journal of surgery, 1969, Volume: 39, Issue:2

    Topics: Animals; Femoral Artery; Heparin; Phenindione; Sheep; Thrombosis

1969
[The diagnostic capability of thrombelastogram, heparin and hirudin tolerance tests during anticoagulant therapy].
    Zeitschrift fur arztliche Fortbildung, 1970, Jun-15, Volume: 64, Issue:12

    Topics: Blood Coagulation; Blood Coagulation Tests; Evaluation Studies as Topic; Heparin; Hirudins; Humans;

1970
[Anticoagulant therapy: physiologic problems].
    Acquisitions medicales recentes, 1970

    Topics: Anticoagulants; Blood Coagulation; Heparin; Humans; Phenindione; Thrombosis

1970
Thromboembolism and its prevention.
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:2

    Topics: Aged; Anticoagulants; Fractures, Bone; Hip Injuries; Humans; Phenindione; Postoperative Complication

1968
Clotting problems with the Teflon-Silastic arteriovenous shunt in patients on regular haemodialysis.
    British medical journal, 1969, Apr-05, Volume: 2, Issue:5648

    Topics: Arteries; Arteriovenous Fistula; Blood Pressure; Blood Vessels; Catheterization; Female; Fluorocarbo

1969
A new type of coagulation inhibitor.
    Thrombosis et diathesis haemorrhagica, 1969, Jun-15, Volume: 21, Issue:3

    Topics: Accidents, Traffic; Anemia; Blood Coagulation Disorders; Blood Coagulation Tests; Bone Marrow Examin

1969
[Diagnosis, prevention and treatment of hemorrhage and thrombosis following annuloplasty and prosthesis of the mitral valve under conditions of extracorporeal circulation].
    Kardiologiia, 1969, Volume: 9, Issue:4

    Topics: Anticoagulants; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Transfusion; Diagnosis,

1969
[Acute arterial obliteration. Thrombolysis with streptokinase. Cure].
    Semaine therapeutique, 1964, Volume: 40, Issue:9

    Topics: Coronary Disease; Femoral Artery; Heparin; Humans; Hydrocortisone; Male; Middle Aged; Phenindione; S

1964
[Effects and side-effects in long-term use of coumarin and indandione derivatives].
    Thrombosis et diathesis haemorrhagica. Supplementum, 1964, Volume: 12

    Topics: Coumarins; Humans; Phenindione; Thrombophlebitis; Thrombosis

1964
Control of anticoagulant therapy in hospital.
    Angiology, 1966, Volume: 17, Issue:5

    Topics: Anticoagulants; Blood Coagulation Tests; Humans; Myocardial Infarction; Phenindione; Thrombosis

1966
General principles of anticoagulant therapy; criteria of effectiveness.
    Thrombosis et diathesis haemorrhagica. Supplementum, 1966, Volume: 21

    Topics: Adult; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelets; Fibrin; Fibrinogen; Hepa

1966
Anticoagulant prophylaxis against venous thrombosis and pulmonary embolism after injury.
    Thrombosis et diathesis haemorrhagica. Supplementum, 1966, Volume: 21

    Topics: Accidents; Bone and Bones; Humans; Phenindione; Pulmonary Embolism; Thrombophlebitis; Thrombosis; Wo

1966