Page last updated: 2024-11-02

phenindione and Thrombophlebitis

phenindione has been researched along with Thrombophlebitis in 65 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Thrombophlebitis: Inflammation of a vein associated with a blood clot (THROMBUS).

Research Excerpts

Excerpt	Relevance	Reference
"Warfarin-induced skin necrosis is a rare but serious complication of oral anticoagulant therapy."	8.78	Warfarin-induced skin necrosis in 2 patients with protein S deficiency: successful reinstatement of warfarin therapy. ( Anderson, DR; Brill-Edwards, P; Walker, I, 1992)
"Warfarin-induced skin necrosis is a rare but serious complication of oral anticoagulant therapy."	4.78	Warfarin-induced skin necrosis in 2 patients with protein S deficiency: successful reinstatement of warfarin therapy. ( Anderson, DR; Brill-Edwards, P; Walker, I, 1992)
"Fluindione was withdrawn and the ulcer healed completely within a month."	1.40	[Recurrent pyoderma gangrenosum-like ulcers induced by oral anticoagulants]. ( Balme, B; Ben-Said, B; Bérard, F; Debarbieux, S; Depaepe, L; Nicolas, JF; Nosbaum, A; Paret, N; Pralong, P, 2014)

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	62 (95.38)	18.7374
1990's	2 (3.08)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (1.54)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Pralong, P	1
Debarbieux, S	1
Paret, N	1
Balme, B	1
Depaepe, L	1
Nosbaum, A	1
Ben-Said, B	1
Nicolas, JF	1
Bérard, F	1
TOWNSEND, SR	1
FAY, KJ	1
DOWNING, JR	1
LAING, R	1
CAMERON, DG	1
MAKOUS, N	1
VANDER VEER, JB	1
ROLANDI, L	1
DE DOMINICIS, E	1
HARPER, BF	1
JOHNSON, R	1
MALAGOLI, F	1
SEVITT, S	4
INNES, D	1
HORSBURGH, AG	1
LEVI, AJ	1
STACHER, A	1
WEITGASSER, H	1
LAUFMAN, H	1
MARTINOT, M	1
BUFFIN, RP	1
SMITH, EK	1
EASTHAM, RD	4
MORGAN, EH	1
BANWELL, A	1
LOMBARD, G	1
MOSCHOS, CB	1
WONG, PC	1
SISE, HS	1
BROWSE, NL	3
JAMES, DC	1
BELDING, HH	1
NALBANDIAN, RM	1
MADER, IJ	1
BARRETT, JL	1
PEARCE, JF	1
RUPP, EC	1
SMITH, K	1
CHAUVIN, H	1
KONIUKHOV, SG	1
DELLA PORTA, M	1
GALLAGHER, NG	1
Gormsen, J	2
Laursen, B	1
Lewis, RJ	1
Spivack, M	1
Spaet, TH	1
Maragall, S	1
Labal, F	1
Monteagudo, J	1
Pistorius, MA	1
Said, L	1
Planchon, B	1
Lavrinovitsch, TS	1
Petuchova, LI	1
Slutskii, LI	1
Anderson, DR	1
Brill-Edwards, P	1
Walker, I	1
Rojas, G	1
Barja, P	1
Bustos, ME	1
Zapata, C	1
Meiland, HT	1
Lenstrup, C	1
Wadt, J	1
Drapkin, A	1
Merskey, C	1
Cunliffe, WJ	1
Menon, IS	1
Larcan, A	1
Bertrand, P	1
Richon, J	1
Calamai, M	1
Straub, PW	1
Fearn, CB	1
Butterfield, WC	1
Neviaser, RJ	1
Roberts, MP	1
Silver, JR	2
Forbes, CD	1
Prentice, CR	1
Preston, FE	1
Edwards, IR	1
Wright, IS	1
Johnson, DC	1
Reeve, TS	1
Nicholls, MG	1
Heale, WF	1
Wingfield, JG	1
Domenet, JG	1
Evans, DW	1
Stephenson, H	1
Moulton, A	1
Mason, JR	1
Lewinski, U	1
Liberman, UA	1
De Vries, A	1
Lund, JO	1
Saha, GL	1
Serova, EV	1
Marx, R	1
Avis, PR	1
Raper, AB	1
Geidel, H	1
Helbig, A	1

Reviews

5 reviews available for phenindione and Thrombophlebitis

Article	Year
[Anticoagulant therapy]. Medicina clinica, 1984, Mar-10, Volume: 82, Issue:9 Topics: Anticoagulants; Coumarins; Embolism; Heart Valve Prosthesis; Heparin; Humans; Intracranial Embolism	1984
Warfarin-induced skin necrosis in 2 patients with protein S deficiency: successful reinstatement of warfarin therapy. Haemostasis, 1992, Volume: 22, Issue:3 Topics: Adult; Combined Modality Therapy; Female; Heparin; Humans; Male; Necrosis; Phenindione; Protein S De	1992
[Indications for and hazards of anticoagulant therapy]. Schweizerische medizinische Wochenschrift, 1970, Apr-18, Volume: 100, Issue:16 Topics: Anticoagulants; Cerebrovascular Disorders; Coumarins; Diabetic Angiopathies; Disseminated Intravascu	1970
Anticoagulants. The Practitioner, 1974, Volume: 213, Issue:1276 SPEC Topics: Anticoagulants; Aspirin; Blood Platelet Disorders; Dipyridamole; Enzyme Therapy; Factor IX; Factor V	1974
A critical evaluation of anticoagulant therapy. Geriatrics, 1969, Volume: 24, Issue:3 Topics: Anticoagulants; Blood Coagulation Tests; Cerebral Hemorrhage; Cerebrovascular Disorders; Coumarins;	1969

Trials

2 trials available for phenindione and Thrombophlebitis

Article	Year
Anticoagulant therapy after acute myocardial infarction. Relation of therapeutic benefit to patient's age, sex, and severity of infarction. JAMA, 1972, Oct-30, Volume: 222, Issue:5 Topics: Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetes Com	1972
Anticoagulants in congestive heart failure. British medical journal, 1966, Oct-08, Volume: 2, Issue:5518 Topics: Adult; Clinical Trials as Topic; Female; Heart Failure; Humans; Male; Middle Aged; Phenindione; Pulm	1966

Other Studies

58 other studies available for phenindione and Thrombophlebitis

Article	Year
[Recurrent pyoderma gangrenosum-like ulcers induced by oral anticoagulants]. Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:1 Topics: Aged; Anticoagulants; Bed Rest; Carcinoma, Basal Cell; Diagnosis, Differential; Drug Eruptions; Drug	2014
Phenylindanedione: a useful anticoagulant. Canadian Medical Association journal, 1953, Volume: 69, Issue:2 Topics: Anticoagulants; Humans; Myocardial Infarction; Phenindione; Thrombophlebitis	1953
Severe drug sensitivity reaction to phenindione (phenylindandione). Journal of the American Medical Association, 1954, Jun-19, Volume: 155, Issue:8 Topics: Hepatitis; Hepatitis A; Humans; Jaundice; Phenindione; Skin Diseases; Thrombophlebitis	1954
[Use of phynylindanedione in obstetrical and gynecological thrombophlebitis]. L' Ospedale maggiore, 1954, Volume: 42, Issue:9 Topics: Female; Genital Diseases, Female; Gynecology; Humans; Phenindione; Postpartum Period; Thrombophlebit	1954
Phenylindanedione; a deserving anticoagulant. Journal of the Medical Association of Georgia, 1956, Volume: 45, Issue:4 Topics: Anticoagulants; Coronary Disease; Humans; Phenindione; Thrombophlebitis	1956
[Mechanism of action of various anticoagulant drugs used in the therapy of obstetrical & gynecological phlebothrombosis & thrombophlebitis]. Annali di ostetricia e ginecologia, 1956, Volume: 78, Issue:8 Topics: Anticoagulants; Ethyl Biscoumacetate; Female; Genital Diseases, Female; Humans; Phenindione; Pregnan	1956
EVIDENCE AGAINST "REBOUND" THROMBOSIS AFTER STOPPING ORAL ANTICOAGULANT DRUGS. Lancet (London, England), 1963, Nov-09, Volume: 2, Issue:7315 Topics: Anticoagulants; Coronary Disease; Humans; Phenindione; Thrombophlebitis; Thrombosis	1963
HAEMATOCELE OF THE GALL-BLADDER. The British journal of surgery, 1963, Volume: 50 Topics: Cholecystitis; Gallbladder Diseases; Geriatrics; Hematocele; Hemorrhage; Heparin; Humans; Laparotomy	1963
[ON THE PATHOGENESIS OF SKIN NECROSIS IN ANTICOAGULANT THERAPY]. Wiener klinische Wochenschrift, 1963, Nov-15, Volume: 75 Topics: Anticoagulants; Coumarins; Estrogens; Female; Gangrene; Heparin; Humans; Necrosis; Phenindione; Preg	1963
[PHENYLINDANDIONE, A NEW LOCAL ANTICOAGULANT]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1963, Aug-01, Volume: 35 Topics: Anticoagulants; Frostbite; Phenindione; Thrombophlebitis; Vascular Diseases	1963
SUPERIORITY OF HEPARIN OVER PROTHROMBIN DEPRESSANTS IN THE TREATMENT OF THROMBOPHLEBITIS AND ITS SEQUELAE. The Surgical clinics of North America, 1964, Volume: 44 Topics: Dicumarol; Enzyme Inhibitors; Heparin; Phenindione; Postoperative Complications; Prothrombin; Thromb	1964
[USE OF PHENYLINDANEDIONE IN SURGERY]. Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1964, Volume: 9 Topics: Cardiac Surgical Procedures; Humans; Phenindione; Postoperative Care; Preoperative Care; Thoracic Su	1964
PREVENTION OF THROMBOEMBOLIC PHENOMENA IN PATIENTS WITH FRACTURED HIPS. Lancet (London, England), 1964, May-23, Volume: 1, Issue:7343 Topics: Anticoagulants; Fractures, Bone; Hip; Humans; Phenindione; Prothrombin Time; Pulmonary Embolism; Thr	1964
[THE TREATMENT OF VENOUS THROMBOSIS]. Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141 Topics: Anticoagulants; Blood Coagulation Tests; Coumarins; Exercise Therapy; Fibrinolysin; Heparin; Heparin	1964
MULTIPLE MIGRATORY THROMBOPHLEBITIS IN MALIGNANT DISEASE. Guy's Hospital reports, 1964, Volume: 113 Topics: Adenocarcinoma; Humans; Lung Neoplasms; Lymphatic Metastasis; Neoplasm Recurrence, Local; Neoplasms;	1964
PLASMA HYPERCOAGULABILITY IN PATIENTS WITH CARCINOMA AND AFTER HAEMORRHAGE. Lancet (London, England), 1964, Sep-12, Volume: 2, Issue:7359 Topics: Blood Coagulation Disorders; Blood Coagulation Tests; Gastrointestinal Hemorrhage; Hemophilia A; Hem	1964
HENOCH-SCHOENLEIN PURPURA; COMPLICATED BY DEEP VEIN THROMBOSIS, SUBARACHNOID HAEMORRHAGE AND PARAPLEGIA. Nursing times, 1964, Jun-26, Volume: 60 Topics: Anemia; Anemia, Hypochromic; Chlorpromazine; Heparin; Humans; IgA Vasculitis; Iron; Methenamine; Nan	1964
[RESULT OF TREATMENT OF RETINAL VENOUS THROMBOSES BY PROLONGED ANTICOAGULANT TREATMENTS. RETINOGRAPHIC CONTROL]. Bulletins et memoires de la Societe francaise d'ophtalmologie, 1963, Volume: 76 Topics: Anticoagulants; Ethyl Biscoumacetate; Humans; Ophthalmology; Ophthalmoscopy; Phenindione; Retinal Ve	1963
CONTROLLED STUDY OF THE EFFECTIVE LEVEL OF LONG-TERM ANTICOAGULATION. JAMA, 1964, Nov-30, Volume: 190 Topics: Anticoagulants; Biomedical Research; Blood Coagulation Tests; Cerebrovascular Disorders; Coronary Di	1964
STREPTOKINASE AND PULMONARY EMBOLISM. Lancet (London, England), 1964, Nov-14, Volume: 2, Issue:7368 Topics: Aminocaproates; Aminocaproic Acid; Biomedical Research; Blood Coagulation Tests; Deoxyribonuclease I	1964
USE OF ANTICOAGULANTS IN THE PREVENTION OF VENOUS THROMBOEMBOLIC DISEASE IN POSTOPERATIVE PATIENTS. Archives of surgery (Chicago, Ill. : 1960), 1965, Volume: 90 Topics: Acenocoumarol; Anticoagulants; Dicumarol; Drug Therapy; Heparin; Phenindione; Postoperative Complica	1965
PETECHIAE, ECCHYMOSES, AND NECROSIS OF SKIN INDUCED BY COUMARIN CONGENERS: RARE, OCCASIONALLY LETHAL COMPLICATION OF ANTICOAGULANT THERAPY. JAMA, 1965, May-17, Volume: 192 Topics: Acenocoumarol; Anticoagulants; Coumarins; Dicumarol; Drug Therapy; Ecchymosis; Ethyl Biscoumacetate;	1965
ACUTE RENAL FAILURE IN PHENINDIONE SENSITIVITY. British medical journal, 1965, Jul-03, Volume: 2, Issue:5452 Topics: Acute Kidney Injury; Biopsy; Drug Eruptions; Drug Therapy; Myocardial Infarction; Pathology; Phenind	1965
[THE PREVENTION OF POSTOPERATIVE PHLEBITIS FOLLOWING PROSTATECTOMY]. Journal d'urologie et de nephrologie, 1965, Volume: 71 Topics: Humans; Male; Phenindione; Phlebitis; Postoperative Complications; Prostatectomy; Thrombophlebitis	1965
[RESULTS OF CLINICAL TRIALS WITH THE ANTICOAGULANT OMEFIN]. Sovetskaia meditsina, 1964, Volume: 27 Topics: Anticoagulants; Phenindione; Thrombophlebitis; Vascular Surgical Procedures	1964
[Experience with a new anticoagulant: 2-phenyl-1,3-indanedione]. Minerva ginecologica, 1955, May-15, Volume: 7, Issue:9 Topics: Anticoagulants; Female; Humans; Indans; Phenindione; Postpartum Period; Thrombophlebitis	1955
Prevention of venous thrombosis and pulmonary embolism in injured patients. A trial of anticoagulant prophylaxis with phenindione in middle-aged and elderly patients with fractured necks of femur. Lancet (London, England), 1959, Dec-05, Volume: 2, Issue:7110 Topics: Aged; Anticoagulants; Child; Femur Neck; Humans; Infant; Middle Aged; Neck; Phenindione; Pulmonary E	1959
Treatment of acute phlebothrombosis with streptase. Acta medica Scandinavica, 1967, Volume: 181, Issue:3 Topics: Blood Coagulation Tests; Female; Heparin; Humans; Male; Middle Aged; Phenindione; Radiography; Strep	1967
Warfarin resistance. The American journal of medicine, 1967, Volume: 42, Issue:4 Topics: Adult; Biological Assay; Humans; Male; Phenindione; Prothrombin Time; Thrombophlebitis; Warfarin	1967
[Comparative study of the efficacy of a low dose of antivitamin K and a preventive dose of low molecular weight heparin in the prevention of relapses of deep venous thrombosis after curative treatment in the aged subject]. Journal des maladies vasculaires, 1994, Volume: 19, Issue:1 Topics: 4-Hydroxycoumarins; Aged; Anticoagulants; Dose-Response Relationship, Drug; Hemorrhage; Humans; Inde	1994
The prevention of deep vein thrombosis and pulmonary embolism by pharmacological methods. Triangle; the Sandoz journal of medical science, 1977, Volume: 16, Issue:1 Topics: Dextrans; Heparin; Humans; Injections, Subcutaneous; Phenindione; Pulmonary Embolism; Thrombophlebit	1977
[A comparative investigation of acetylsalicyclic acid and indirect anticoagulants for the prophylaxis of venous thromboses in patients with an orthopedic-traumatologic case history (author's transl)]. Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1976, Volume: 114, Issue:5 Topics: Aspirin; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteotomy; Phenindione; Postoperative C	1976
The efficacy of long-term oral anticoagulant therapy and its laboratory assessment. Journal of clinical pathology, 1975, Volume: 28, Issue:3 Topics: Adult; Blood Coagulation; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Myocardial Infarc	1975
[Familial deficiency of antithrombin III]. Revista medica de Chile, 1988, Volume: 116, Issue:1 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticoagulants; Antithrombin III Deficiency; Cleft L	1988
[Phenindione anticoagulant treatment during pregnancy]. Ugeskrift for laeger, 1987, Dec-14, Volume: 149, Issue:51 Topics: Adolescent; Adult; Drug Therapy, Combination; Female; Heparin; Humans; Infant, Newborn; Phenindione;	1987
Treatment of Behcet's syndrome with phenformin and ethyloestrenol. Lancet (London, England), 1969, Jun-21, Volume: 1, Issue:7608 Topics: Adult; Behcet Syndrome; Ethylestrenol; Fibrinolysis; Heparin; Humans; Leg Ulcer; Male; Phenformin; P	1969
[Necrotic and bullous skin complications of anti-vitamin K]. La Presse medicale, 1968, May-22, Volume: 76, Issue:25 Topics: Adult; Aged; Drug Eruptions; Ethyl Biscoumacetate; Female; Humans; Male; Necrosis; Phenindione; Post	1968
Iliacus haematoma syndrome as a complication of anticoagulant therapy. British medical journal, 1968, Oct-12, Volume: 4, Issue:5623 Topics: Aged; Bronchitis; Femoral Nerve; Hematoma; Humans; Hypertension; Male; Peripheral Nervous System Dis	1968
Femoral neuropathy and anticoagulants. Annals of surgery, 1972, Volume: 176, Issue:1 Topics: Adult; Aged; Anticoagulants; Female; Femoral Nerve; Heparin; Humans; Male; Middle Aged; Peripheral N	1972
Blood and neoplastic diseases. Thrombosis: treatment and prophylaxis. British medical journal, 1974, Oct-12, Volume: 4, Issue:5936 Topics: Anticoagulants; Blood Coagulation; Catheterization; Clot Retraction; Electric Stimulation; Embolism;	1974
The prophylactic use of anticoagulant therapy in the prevention of pulmonary emboli in one hundred consecutive spinal injury patients. Paraplegia, 1974, Volume: 12, Issue:3 Topics: Adolescent; Adult; Anticoagulants; Drug Evaluation; Humans; Male; Middle Aged; Phenindione; Pulmonar	1974
Postpartum purpura fulminans: successful management with streptokinase. British medical journal, 1973, Aug-11, Volume: 3, Issue:5875 Topics: Adult; Female; Heparin; Humans; Phenindione; Phlebography; Pregnancy; Puerperal Disorders; Purpura;	1973
[Treatment of acute phlebothrombosis with streptokinase according to a standard schema]. Ugeskrift for laeger, 1972, Jun-19, Volume: 134, Issue:25 Topics: Female; Fibrinolysis; Heparin; Humans; Phenindione; Pregnancy; Streptokinase; Thrombophlebitis; Time	1972
The effects and clinical significance of heparin and phenindione on a standard experimental femoral venous thrombus. The Australian and New Zealand journal of surgery, 1969, Volume: 39, Issue:2 Topics: Animals; Femoral Vein; Heparin; Phenindione; Sheep; Thrombophlebitis	1969
Phenindione sensitivity and acute renal failure. The New Zealand medical journal, 1970, Volume: 71, Issue:455 Topics: Acute Kidney Injury; Albuminuria; Drug Hypersensitivity; Humans; Kidney Papillary Necrosis; Kidney T	1970
Anticoagulation for antenatal thrombo-embolic disease. The Journal of obstetrics and gynaecology of the British Commonwealth, 1969, Volume: 76, Issue:6 Topics: Delivery, Obstetric; Female; Heparin; Humans; Phenindione; Postpartum Hemorrhage; Pregnancy; Pregnan	1969
Prophylactic anticoagulant therapy against pulmonary emboli in acute paraplegia. British medical journal, 1970, May-09, Volume: 2, Issue:5705 Topics: Adolescent; Adult; Aged; Anticoagulants; Child; Female; Humans; Male; Middle Aged; Paraplegia; Pheni	1970
Haemorrhage-induced breast gangrene. The British journal of surgery, 1970, Volume: 57, Issue:9 Topics: Aged; Breast Diseases; Female; Gangrene; Hemorrhage; Heparin; Humans; Middle Aged; Phenindione; Pulm	1970
[An unusual complication of treatment with diphenadion]. Harefuah, 1970, May-01, Volume: 78, Issue:9 Topics: Aged; Female; Humans; Necrosis; Phenindione; Thrombophlebitis	1970
[Thrombophlebitis in the upper limbs complicated by gangrene of the hands]. Ugeskrift for laeger, 1967, Jan-19, Volume: 129, Issue:3 Topics: Aged; Amputation, Surgical; Arm; Female; Gangrene; Hand; Humans; Phenindione; Thrombophlebitis	1967
Improved control of long-term anticoagulant therapy. British medical journal, 1968, May-11, Volume: 2, Issue:5601 Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Female; Heart Valve Diseases; Humans; Male; Mi	1968
Defibrination syndrome in phlegmasia ceruleaolens. Postgraduate medical journal, 1969, Volume: 45, Issue:519 Topics: Adolescent; Afibrinogenemia; Blood Coagulation Disorders; Heparin; Humans; Male; Phenindione; Thromb	1969
[Treatment of thrombophlebitis of the lower limbs in polyclinical practice]. Khirurgiia, 1965, Volume: 41, Issue:9 Topics: Acenocoumarol; Adult; Blood Coagulation Tests; Ethyl Biscoumacetate; Female; Humans; Leg; Male; Midd	1965
[Effects and side-effects in long-term use of coumarin and indandione derivatives]. Thrombosis et diathesis haemorrhagica. Supplementum, 1964, Volume: 12 Topics: Coumarins; Humans; Phenindione; Thrombophlebitis; Thrombosis	1964
Seasonal fluctuation in adhesive platelets during long-term anticoagulant therapy. British journal of haematology, 1966, Volume: 12, Issue:1 Topics: Aged; Blood Cell Count; Blood Platelets; Carotid Artery Diseases; Coronary Disease; Humans; Male; Mi	1966
Anticoagulant prophylaxis against venous thrombosis and pulmonary embolism after injury. Thrombosis et diathesis haemorrhagica. Supplementum, 1966, Volume: 21 Topics: Accidents; Bone and Bones; Humans; Phenindione; Pulmonary Embolism; Thrombophlebitis; Thrombosis; Wo	1966
Experiences in the control of long-term anticoagulant treatment. Bristol medico-chirurgical journal (1963), 1966, Volume: 81, Issue:302 Topics: Adult; Aged; Anticoagulants; Carotid Artery Diseases; Coronary Disease; Female; Humans; Male; Middle	1966
[Change from athrombone to chlorathrombone]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Jul-15, Volume: 21, Issue:14 Topics: Anticoagulants; Arrhythmias, Cardiac; Ataxia; Female; Humans; Male; Myocardial Infarction; Phenindio	1966