Page last updated: 2024-11-02

phenindione and Pregnancy

phenindione has been researched along with Pregnancy in 19 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" A larger study is necessary to confirm the relationship between the dosage and outcome."1.31Oral anticoagulation therapy during pregnancy in patients with mechanical mitral valves: a prospective study. ( Allam, H; Hassouna, A, 2001)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199016 (84.21)18.7374
1990's0 (0.00)18.2507
2000's3 (15.79)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
d'Ythurbide, G1
Rousset, P1
Carbonne, B1
Cabane, J1
Fardet, L1
Tiev, K1
Kettaneh, A1
MALAGOLI, F1
STACHER, A1
ROSCOE, MH1
BOCQUET, L1
Schaefer, C1
Hannemann, D1
Meister, R1
Eléfant, E1
Paulus, W1
Vial, T1
Reuvers, M1
Robert-Gnansia, E1
Arnon, J1
De Santis, M1
Clementi, M1
Rodriguez-Pinilla, E1
Dolivo, A1
Merlob, P1
Hassouna, A1
Allam, H1
Morris, GK1
Shaul, WL1
Hall, JG1
Rojas, G1
Barja, P1
Bustos, ME1
Zapata, C1
Meiland, HT1
Lenstrup, C1
Wadt, J1
Larcan, A1
Bertrand, P1
Richon, J1
Calamai, M1
Preston, FE1
Edwards, IR1
Gormsen, J1
Buxbaum, A1
Aygen, MM1
Shahin, W1
Levy, MJ1
Ekerling, B1
Duncan, ID1
Coyle, MG1
Walker, J1
Wingfield, JG1
Jenkins, BS1
Braimbridge, MV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety And Efficacy of Low Dose Oral Anticoagulants And Aspirin Therapy Throughout Pregnancy In Patients With Mechanical Heart Valves Prosthesis[NCT01758640]Phase 3200 participants (Actual)Interventional2010-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenindione and Pregnancy

ArticleYear
[ANTICOAGULANTS AND PREGNANCY. HAZARDS FOR THE INFANT].
    Coeur et medecine interne, 1964, Volume: 59

    Topics: Anticoagulants; Coumarins; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Phenindione; Pre

1964

Other Studies

18 other studies available for phenindione and Pregnancy

ArticleYear
[Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome].
    La Revue de medecine interne, 2009, Volume: 30, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Drug Therapy, Co

2009
[Mechanism of action of various anticoagulant drugs used in the therapy of obstetrical & gynecological phlebothrombosis & thrombophlebitis].
    Annali di ostetricia e ginecologia, 1956, Volume: 78, Issue:8

    Topics: Anticoagulants; Ethyl Biscoumacetate; Female; Genital Diseases, Female; Humans; Phenindione; Pregnan

1956
[ON THE PATHOGENESIS OF SKIN NECROSIS IN ANTICOAGULANT THERAPY].
    Wiener klinische Wochenschrift, 1963, Nov-15, Volume: 75

    Topics: Anticoagulants; Coumarins; Estrogens; Female; Gangrene; Heparin; Humans; Necrosis; Phenindione; Preg

1963
URINE IN ACUTE AND CHRONIC RENAL FAILURE.
    British medical journal, 1964, Apr-25, Volume: 1, Issue:5390

    Topics: Acute Kidney Injury; Blood Chemical Analysis; Female; Kidney Diseases; Kidney Failure, Chronic; Osmo

1964
Vitamin K antagonists and pregnancy outcome. A multi-centre prospective study.
    Thrombosis and haemostasis, 2006, Volume: 95, Issue:6

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Acenocoumarol; Adverse Drug R

2006
Oral anticoagulation therapy during pregnancy in patients with mechanical mitral valves: a prospective study.
    Cardiovascular surgery (London, England), 2001, Volume: 9, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anticoagulants; Dipyridamole; Dose-Response Relations

2001
Oral anticoagulant prophylaxis against venous thrombolism.
    Scottish medical journal, 1978, Volume: 23, Issue:4

    Topics: Administration, Oral; Anticoagulants; Female; Humans; Phenindione; Postoperative Complications; Preg

1978
Multiple congenital anomalies associated with oral anticoagulants.
    American journal of obstetrics and gynecology, 1977, Jan-15, Volume: 127, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Female; Humans; Infant, Newborn; Male; Phenindione; Pregnancy; W

1977
[Familial deficiency of antithrombin III].
    Revista medica de Chile, 1988, Volume: 116, Issue:1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticoagulants; Antithrombin III Deficiency; Cleft L

1988
[Phenindione anticoagulant treatment during pregnancy].
    Ugeskrift for laeger, 1987, Dec-14, Volume: 149, Issue:51

    Topics: Adolescent; Adult; Drug Therapy, Combination; Female; Heparin; Humans; Infant, Newborn; Phenindione;

1987
The choice of an oral anticoagulant.
    Drug and therapeutics bulletin, 1972, Mar-31, Volume: 10, Issue:7

    Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Dicumarol; Drug Hypersensitivity; Ethyl Biscoum

1972
[Necrotic and bullous skin complications of anti-vitamin K].
    La Presse medicale, 1968, May-22, Volume: 76, Issue:25

    Topics: Adult; Aged; Drug Eruptions; Ethyl Biscoumacetate; Female; Humans; Male; Necrosis; Phenindione; Post

1968
Postpartum purpura fulminans: successful management with streptokinase.
    British medical journal, 1973, Aug-11, Volume: 3, Issue:5875

    Topics: Adult; Female; Heparin; Humans; Phenindione; Phlebography; Pregnancy; Puerperal Disorders; Purpura;

1973
[Treatment of acute phlebothrombosis with streptokinase according to a standard schema].
    Ugeskrift for laeger, 1972, Jun-19, Volume: 134, Issue:25

    Topics: Female; Fibrinolysis; Heparin; Humans; Phenindione; Pregnancy; Streptokinase; Thrombophlebitis; Time

1972
Pregnancy in patients with prosthetic heart valves.
    Chest, 1971, Volume: 59, Issue:6

    Topics: Abortion, Missed; Abortion, Spontaneous; Adult; Anticoagulants; Female; Fetal Death; Fetus; Heart Va

1971
Management and treatment of 34 cases of antepartum thromboembolism.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1971, Volume: 78, Issue:10

    Topics: Age Factors; Blood Group Antigens; Dextrans; Diethylstilbestrol; Female; Hemoglobinometry; Heparin;

1971
Anticoagulation for antenatal thrombo-embolic disease.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1969, Volume: 76, Issue:6

    Topics: Delivery, Obstetric; Female; Heparin; Humans; Phenindione; Postpartum Hemorrhage; Pregnancy; Pregnan

1969
Management of anticoagulant therapy during pregnancy in patients with prosthetic heart valves.
    Thorax, 1971, Volume: 26, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Anticoagulants; Aortic Valve; Aortic Valve Insufficiency; Female

1971