phenindione has been researched along with Necrosis in 19 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Warfarin-induced skin necrosis is a rare but serious complication of oral anticoagulant therapy." | 8.78 | Warfarin-induced skin necrosis in 2 patients with protein S deficiency: successful reinstatement of warfarin therapy. ( Anderson, DR; Brill-Edwards, P; Walker, I, 1992) |
| "In the setting of protein C deficiency, skin necrosis, which occurs most often at the initial phase of oral anticoagulants therapy, is a rare side effect." | 5.40 | Skin necrosis due to fluindione treatment: a rare but serious complication. ( Alhene Gelas, M; Avril, MF; Beqqal, K; Dupin, N; Flaujac, C; Gorin, I; Hassam, B; Horellou, MH; Jacobelli, S; Philippe, A, 2014) |
| "Cutaneous necrosis is a rare complication of vitamin K antagonist therapy." | 5.38 | [Skin necrosis during long-term fluindione treatment revealing protein C deficiency]. ( Alhenc-Gelas, M; Batard, ML; Cribier, B; Mazurier, I; Merklen-Djafri, C; Roth, B; Samama, MM; Tortel, MC, 2012) |
| "Warfarin-induced skin necrosis is a rare but serious complication of oral anticoagulant therapy." | 4.78 | Warfarin-induced skin necrosis in 2 patients with protein S deficiency: successful reinstatement of warfarin therapy. ( Anderson, DR; Brill-Edwards, P; Walker, I, 1992) |
| "Skin necrosis is due to a transient hypercoagulable state during the initiation of vitamin K antagonist treatment due to an imbalance between pro- and anticoagulant factors." | 1.46 | [Skin necrosis with vitamin K antagonists: An imbalance between coagulant and anticoagulant factors]. ( Closs-Prophette, F; Maillard, H; Osmaeva, K; Vildy, S, 2017) |
| "In the setting of protein C deficiency, skin necrosis, which occurs most often at the initial phase of oral anticoagulants therapy, is a rare side effect." | 1.40 | Skin necrosis due to fluindione treatment: a rare but serious complication. ( Alhene Gelas, M; Avril, MF; Beqqal, K; Dupin, N; Flaujac, C; Gorin, I; Hassam, B; Horellou, MH; Jacobelli, S; Philippe, A, 2014) |
| "Cutaneous necrosis is a rare complication of vitamin K antagonist therapy." | 1.38 | [Skin necrosis during long-term fluindione treatment revealing protein C deficiency]. ( Alhenc-Gelas, M; Batard, ML; Cribier, B; Mazurier, I; Merklen-Djafri, C; Roth, B; Samama, MM; Tortel, MC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beqqal, K | 1 |
| Horellou, MH | 1 |
| Philippe, A | 1 |
| Alhene Gelas, M | 1 |
| Flaujac, C | 1 |
| Gorin, I | 1 |
| Jacobelli, S | 1 |
| Dupin, N | 1 |
| Hassam, B | 1 |
| Avril, MF | 1 |
| Vildy, S | 1 |
| Osmaeva, K | 1 |
| Closs-Prophette, F | 1 |
| Maillard, H | 1 |
| Trad, S | 1 |
| Saadoun, D | 1 |
| Barete, S | 1 |
| Frances, C | 1 |
| Piette, JC | 1 |
| Wechsler, B | 1 |
| Jefferson, J | 1 |
| Bezier, M | 1 |
| Perceau, G | 1 |
| Reguiai, Z | 1 |
| Remy-Leroux, V | 1 |
| Tchen, T | 1 |
| Durlach, A | 1 |
| Grange, F | 1 |
| Nguyen, P | 1 |
| Bernard, P | 1 |
| Merklen-Djafri, C | 1 |
| Mazurier, I | 1 |
| Samama, MM | 1 |
| Alhenc-Gelas, M | 1 |
| Tortel, MC | 1 |
| Cribier, B | 1 |
| Roth, B | 2 |
| Batard, ML | 1 |
| STACHER, A | 1 |
| NALBANDIAN, RM | 1 |
| MADER, IJ | 1 |
| BARRETT, JL | 1 |
| PEARCE, JF | 1 |
| RUPP, EC | 1 |
| Debarbieux, S | 1 |
| Causeret, AS | 1 |
| Trzeciak, MC | 1 |
| Claudy, A | 1 |
| Eldon, K | 1 |
| Lindahl, F | 1 |
| Tong, D | 2 |
| Anderson, DR | 1 |
| Brill-Edwards, P | 1 |
| Walker, I | 1 |
| Dalley, D | 1 |
| Kelleher, PR | 1 |
| Larcan, A | 1 |
| Bertrand, P | 1 |
| Richon, J | 1 |
| Calamai, M | 1 |
| Linke, H | 1 |
| Desai, SN | 1 |
| Lewinski, U | 1 |
| Liberman, UA | 1 |
| De Vries, A | 1 |
| Bour, H | 1 |
| Renoux, M | 1 |
| Guy-Grand, B | 1 |
| Tutin, M | 1 |
| Costil, J | 1 |
| Escande, C | 1 |
1 review available for phenindione and Necrosis
| Article | Year |
|---|---|
Warfarin-induced skin necrosis in 2 patients with protein S deficiency: successful reinstatement of warfarin therapy.
Topics: Adult; Combined Modality Therapy; Female; Heparin; Humans; Male; Necrosis; Phenindione; Protein S De | 1992 |
18 other studies available for phenindione and Necrosis
| Article | Year |
|---|---|
Skin necrosis due to fluindione treatment: a rare but serious complication.
Topics: Adult; Anticoagulants; Female; Humans; Necrosis; Occlusive Dressings; Phenindione; Protein C Deficie | 2014 |
[Skin necrosis with vitamin K antagonists: An imbalance between coagulant and anticoagulant factors].
Topics: 4-Hydroxycoumarins; Adolescent; Amputation, Surgical; Anticoagulants; Breast; Coagulants; Female; Ha | 2017 |
[Necrotizing folliculitis in Behçet's disease].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Bacterial Toxins; Behcet | 2009 |
Skin pigmentation by phenindione.
Topics: Drug Therapy; Humans; Necrosis; Phenindione; Skin Pigmentation | 1966 |
[Necrotic leg ulcers induced by vitamin K antagonists: five cases].
Topics: Acenocoumarol; Activated Protein C Resistance; Aged; Aged, 80 and over; Anticoagulants; Diabetic Ang | 2011 |
[Skin necrosis during long-term fluindione treatment revealing protein C deficiency].
Topics: Abdominal Wall; Aged; Anticoagulants; Biopsy; Capillaries; Drug Eruptions; Female; Genetic Carrier S | 2012 |
[ON THE PATHOGENESIS OF SKIN NECROSIS IN ANTICOAGULANT THERAPY].
Topics: Anticoagulants; Coumarins; Estrogens; Female; Gangrene; Heparin; Humans; Necrosis; Phenindione; Preg | 1963 |
PETECHIAE, ECCHYMOSES, AND NECROSIS OF SKIN INDUCED BY COUMARIN CONGENERS: RARE, OCCASIONALLY LETHAL COMPLICATION OF ANTICOAGULANT THERAPY.
Topics: Acenocoumarol; Anticoagulants; Coumarins; Dicumarol; Drug Therapy; Ecchymosis; Ethyl Biscoumacetate; | 1965 |
[A necrotic plaque on the thigh].
Topics: Adult; Anticoagulants; Drug Eruptions; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; M | 2003 |
[Skin necrosis after treatment with phenindione (Dindevan)].
Topics: Aged; Drug Eruptions; Female; Humans; Necrosis; Phenindione | 1980 |
Letter: Heparin therapy in Coumadin breast necrosis.
Topics: Breast Diseases; Female; Heparin; Humans; Middle Aged; Necrosis; Phenindione; Warfarin | 1976 |
Skin sensitivity to phenindione. Report of a case.
Topics: Drug Eruptions; Female; Foot Dermatoses; Hand Dermatoses; Hemorrhage; Humans; Middle Aged; Necrosis; | 1966 |
[Necrotic and bullous skin complications of anti-vitamin K].
Topics: Adult; Aged; Drug Eruptions; Ethyl Biscoumacetate; Female; Humans; Male; Necrosis; Phenindione; Post | 1968 |
[Coumarin necroses--pathogenesis, clinical picture and therapy (with reference to 6 own cases)].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Cardiac Glycosides; Coumarins; Drug Combinations; G | 1971 |
Extensive skin necrosis following anticoagulant therapy.
Topics: Adult; Female; Heparin; Humans; Middle Aged; Necrosis; Phenindione; Skin Diseases; Skin Transplantat | 1967 |
[An unusual complication of treatment with diphenadion].
Topics: Aged; Female; Humans; Necrosis; Phenindione; Thrombophlebitis | 1970 |
Haemorrhagic necrosis of the breast complicating anticoagulant therapy and mitral stenosis.
Topics: Breast Diseases; Female; Hemorrhage; Humans; Middle Aged; Mitral Valve Stenosis; Necrosis; Phenindio | 1971 |
[Horton's disease with bilateral eye involvment, cutaneous and lingual necrosis].
Topics: Aged; Angiography; Blindness; Cortisone; Dexamethasone; Ergotamine; Female; Gangrene; Giant Cell Art | 1969 |