phenindione has been researched along with Muscular Diseases in 3 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(1) Renal failure, either pre-existing or induced by a nephrotoxic drug, increases the risk of adverse effects in patients taking colchicine; (2) Combining colchicines with a macrolide (except for spiramycin) carries a risk of life-threatening pancytopenia; (3) Ciclosporin co-administration can aggravate the neuromuscular adverse effects of colchicine; (4) Combining colchicine with lipid-lowering drugs (statins and fibrates) can cause myopathy; (5) Several mechanisms have been implicated: competition for cytochrome P450 or P-glycoprotein, additive adverse effects (especially on muscle), and colchicine accumulation due to a reduction in its renal excretion; (6) Patients with gout should use colchicine only after failure of symptomatic treatment: ice application, paracetamol, and possibly ibuprofen, a nonsteroidal antiinflammatory drug with well-documented adverse effects; (7) If colchicine is nevertheless used, it should be at the minimum effective dose." | 3.74 | Colchicine: serious interactions. ( , 2008) |
| "We report six cases of spontaneous muscular hematomas occurring in hemiplegic patients receiving anticoagulation therapy using heparin, low-molecular-weight heparin or fluindione." | 3.72 | [Spontaneous muscular haematomas in hemiplegic patients receiving anticoagulation therapy]. ( Chevignard, M; Galimard, N; Mazevet, D; Perrigot, M; Vassilev, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galimard, N | 1 |
| Vassilev, K | 1 |
| Chevignard, M | 1 |
| Perrigot, M | 1 |
| Mazevet, D | 1 |
| Milleret, P | 1 |
| Combe, J | 1 |
3 other studies available for phenindione and Muscular Diseases
| Article | Year |
|---|---|
Colchicine: serious interactions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Clofibric Acid; Colchicine; Cycl | 2008 |
[Spontaneous muscular haematomas in hemiplegic patients receiving anticoagulation therapy].
Topics: Adult; Anticoagulants; Electromyography; Female; Hematoma; Hemiplegia; Heparin, Low-Molecular-Weight | 2004 |
[Hematoma of the iliac psoas muscle complicated by femoral paralysis: a surgical emergency].
Topics: Emergencies; Femoral Nerve; Hematoma; Humans; Male; Middle Aged; Muscular Diseases; Nerve Compressio | 1975 |