phenindione has been researched along with Multiple Myeloma in 1 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine patients with multiple myeloma (n=6) or AL amyloidosis (n=3), including 6 prospective patients, taking fluindione (n=8) or warfarin (n=1), were studied for a total of 10 cycles." | 9.12 | Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis. ( Amoura, Z; Ankri, A; Aymard, G; Berenbaum, F; Cacoub, P; Choquet, S; Costedoat-Chalumeau, N; Hulot, JS; Leblond, V; Lechat, P; Mariette, X; Piette, JC; Sellam, J; Trad, S; Vignes, BL, 2007) |
| "Nine patients with multiple myeloma (n=6) or AL amyloidosis (n=3), including 6 prospective patients, taking fluindione (n=8) or warfarin (n=1), were studied for a total of 10 cycles." | 5.12 | Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis. ( Amoura, Z; Ankri, A; Aymard, G; Berenbaum, F; Cacoub, P; Choquet, S; Costedoat-Chalumeau, N; Hulot, JS; Leblond, V; Lechat, P; Mariette, X; Piette, JC; Sellam, J; Trad, S; Vignes, BL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sellam, J | 1 |
| Costedoat-Chalumeau, N | 1 |
| Amoura, Z | 1 |
| Aymard, G | 1 |
| Choquet, S | 1 |
| Trad, S | 1 |
| Vignes, BL | 1 |
| Hulot, JS | 1 |
| Berenbaum, F | 1 |
| Lechat, P | 1 |
| Cacoub, P | 1 |
| Ankri, A | 1 |
| Mariette, X | 1 |
| Leblond, V | 1 |
| Piette, JC | 1 |
1 trial available for phenindione and Multiple Myeloma
| Article | Year |
|---|---|
Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis.
Topics: Aged; Amyloidosis; Anticoagulants; Blood Coagulation; Creatinine; Dexamethasone; Drug Synergism; Fem | 2007 |