phenindione has been researched along with Heart Valve Diseases in 4 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
| Excerpt | Relevance | Reference |
|---|---|---|
| " A larger study is necessary to confirm the relationship between the dosage and outcome." | 1.31 | Oral anticoagulation therapy during pregnancy in patients with mechanical mitral valves: a prospective study. ( Allam, H; Hassouna, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hassouna, A | 1 |
| Allam, H | 1 |
| Eastham, RD | 2 |
| Kubicek, F | 1 |
| Praschl, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety And Efficacy of Low Dose Oral Anticoagulants And Aspirin Therapy Throughout Pregnancy In Patients With Mechanical Heart Valves Prosthesis[NCT01758640] | Phase 3 | 200 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for phenindione and Heart Valve Diseases
| Article | Year |
|---|---|
Oral anticoagulation therapy during pregnancy in patients with mechanical mitral valves: a prospective study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticoagulants; Dipyridamole; Dose-Response Relations | 2001 |
The efficacy of long-term oral anticoagulant therapy and its laboratory assessment.
Topics: Adult; Blood Coagulation; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Myocardial Infarc | 1975 |
[Clinical experiences with anticoagulant long term treatment of predominantly cardiologic patients].
Topics: Acenocoumarol; Adult; Aged; Angina Pectoris; Anticoagulants; Coronary Disease; Coumarins; Female; He | 1968 |
Improved control of long-term anticoagulant therapy.
Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Female; Heart Valve Diseases; Humans; Male; Mi | 1968 |