Compounds > phenindione
Page last updated: 2024-11-02

phenindione and Embolism, Pulmonary

phenindione has been researched along with Embolism, Pulmonary in 44 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Research Excerpts

ExcerptRelevanceReference
"No data are available on the efficacy and safety of a combination of fondaparinux and thrombolysis in the setting of high to intermediate risk pulmonary embolism (PE)."9.14Safety and efficacy of fondaparinux as an adjunctive treatment to thrombolysis in patients with high and intermediate risk pulmonary embolism. ( Bassand, JP; Bernard, Y; Chopard, R; Descotes-Genon, V; Dutheil, J; Janin, S; Mahemuti, A; Meneveau, N; Schiele, F; Seronde, MF, 2009)
"No data are available on the efficacy and safety of a combination of fondaparinux and thrombolysis in the setting of high to intermediate risk pulmonary embolism (PE)."5.14Safety and efficacy of fondaparinux as an adjunctive treatment to thrombolysis in patients with high and intermediate risk pulmonary embolism. ( Bassand, JP; Bernard, Y; Chopard, R; Descotes-Genon, V; Dutheil, J; Janin, S; Mahemuti, A; Meneveau, N; Schiele, F; Seronde, MF, 2009)
" We report the case of spontaneous hematoma of right angle of the transverse mesocolon associated with a hemoperitoneum in a 32-year-old patient treated by fluindione for pulmonary embolism."3.83[Spontaneous hematoma of right angle of the transverse mesocolon: exceptional complication of anticoagulant therapy with vitamin K]. ( Barro, SD; Guibla, I; Traoré, IA; Zaré, C, 2016)
" The mean phenindione dosage was 72 mg."2.63Assessment of short-anticoagulant administration after cardiac infarction. Report of the Working Party on Anticoagulant Therapy in Coronary Thrombosis to the Medical Research Council. ( , 1969)
"Among subdural hematomas of any cause, the possible role of a previous anticoagulant therapy is stressed in 4,8 to 14% of cases."1.26[Subdural hematoma and anticoagulant therapy]. ( Bret, P; Deruty, R; Desgeorges, M; Lapras, C; Lecuire, J; Prudhon, JL, 1976)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199040 (90.91)18.7374
1990's0 (0.00)18.2507
2000's2 (4.55)29.6817
2010's2 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Salort, A1
Seinturier, C1
Molina, L1
Lévèque, P1
Imbert, B1
Pernod, G1
Traoré, IA1
Zaré, C1
Barro, SD1
Guibla, I1
Janin, S1
Meneveau, N1
Mahemuti, A1
Descotes-Genon, V1
Dutheil, J1
Chopard, R1
Seronde, MF1
Schiele, F1
Bernard, Y1
Bassand, JP1
MARKS, J1
TRUSCOTT, BM1
WITHYCOMBE, JF1
BUZZI, A1
CARBAJAL, B1
FAGAN, DG1
SEVITT, S4
HOLLMAN, A1
WONG, HO1
PERSSON, BM1
BROWSE, NL4
JAMES, DC1
BHARGAVA, RK1
DHOOT, BM1
BELDING, HH1
NALBANDIAN, RM1
MADER, IJ1
BARRETT, JL1
PEARCE, JF1
RUPP, EC1
SMITH, K1
GALLAGHER, NG1
Maragall, S1
Labal, F1
Monteagudo, J1
Goldberg, RJ1
Gore, JM1
Dalen, JE1
Bret, P1
Lecuire, J1
Lapras, C1
Deruty, R1
Desgeorges, M1
Prudhon, JL1
Joly, F1
Valty, J1
Emar, A1
Johnson, R1
Green, JR1
Charnley, J1
Lavrinovitsch, TS1
Petuchova, LI1
Slutskii, LI1
Gruber, UF1
Meiland, HT1
Lenstrup, C1
Wadt, J1
Drapkin, A1
Merskey, C1
Gordon-Smith, IC1
Silver, JR2
Wingfield, JG1
Domenet, JG1
Evans, DW1
Stephenson, H1
Moulton, A1
Mason, JR1
Klepping, C1
Bourgeaux, C1
Villand, J1
Carli, H1
Tong, D1
Eastham, RD2
Little, JM1
Loewenthal, J1
Thomas, ML1
Solan, MJ1
Young, AE1
Lechner, K1
Avis, PR1
Geidel, H1
Helbig, A1

Reviews

2 reviews available for phenindione and Embolism, Pulmonary

ArticleYear
[Anticoagulant therapy].
    Medicina clinica, 1984, Mar-10, Volume: 82, Issue:9

    Topics: Anticoagulants; Coumarins; Embolism; Heart Valve Prosthesis; Heparin; Humans; Intracranial Embolism

1984
The role of anticoagulant therapy in acute myocardial infarction.
    American heart journal, 1984, Volume: 108, Issue:5

    Topics: Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Female; Fibri

1984

Trials

6 trials available for phenindione and Embolism, Pulmonary

ArticleYear
Safety and efficacy of fondaparinux as an adjunctive treatment to thrombolysis in patients with high and intermediate risk pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2009, Volume: 28, Issue:3

    Topics: Aged; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug-Related Side Effects and Adverse React

2009
The role of anticoagulant therapy in acute myocardial infarction.
    American heart journal, 1984, Volume: 108, Issue:5

    Topics: Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Female; Fibri

1984
Prevention of fatal pulmonary embolism in patients with fractures of the neck of the femur.
    Surgery, gynecology & obstetrics, 1985, Volume: 161, Issue:1

    Topics: Aged; Dextrans; Dihydroergotamine; Drug Combinations; Female; Femoral Neck Fractures; Heparin; Hepar

1985
Anticoagulant therapy after acute myocardial infarction. Relation of therapeutic benefit to patient's age, sex, and severity of infarction.
    JAMA, 1972, Oct-30, Volume: 222, Issue:5

    Topics: Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetes Com

1972
Assessment of short-anticoagulant administration after cardiac infarction. Report of the Working Party on Anticoagulant Therapy in Coronary Thrombosis to the Medical Research Council.
    British medical journal, 1969, Feb-08, Volume: 1, Issue:5640

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myoca

1969
Anticoagulants in congestive heart failure.
    British medical journal, 1966, Oct-08, Volume: 2, Issue:5518

    Topics: Adult; Clinical Trials as Topic; Female; Heart Failure; Humans; Male; Middle Aged; Phenindione; Pulm

1966

Other Studies

37 other studies available for phenindione and Embolism, Pulmonary

ArticleYear
[Recurrent deep vein thrombosis and myeloproliferative syndrom: emergence of JAK2 mutation five years after the initial event].
    Journal des maladies vasculaires, 2014, Volume: 39, Issue:3

    Topics: Adult; alpha-Thalassemia; Anticoagulants; Bone Marrow; Erythroblasts; Female; Humans; Janus Kinase 2

2014
[Spontaneous hematoma of right angle of the transverse mesocolon: exceptional complication of anticoagulant therapy with vitamin K].
    The Pan African medical journal, 2016, Volume: 23

    Topics: Adult; Anticoagulants; Female; Hematoma; Hemoperitoneum; Humans; Mesocolon; Phenindione; Pulmonary E

2016
Treatment of venous thrombosis with anticoagulants; review of 1135 cases.
    Lancet (London, England), 1954, Oct-16, Volume: 267, Issue:6842

    Topics: Anticoagulants; Coumarins; Heparin; Humans; Phenindione; Pulmonary Embolism; Thrombosis; Venous Thro

1954
[Clinical evaluation of the anticoagulant, phenylindanedione].
    Medicina panamericana, 1958, Volume: 11, Issue:9-10

    Topics: Anticoagulants; Arteriosclerosis Obliterans; Coronary Disease; Humans; Phenindione; Pulmonary Emboli

1958
PREVENTION OF THROMBOEMBOLIC PHENOMENA FOLLOWING OPERATIONS ON THE NECK OF THE FEMUR.
    Lancet (London, England), 1964, Apr-18, Volume: 1, Issue:7338

    Topics: Arthroplasty; Femoral Neck Fractures; Fracture Fixation; Hemorrhage; Humans; Immobilization; Phenind

1964
PREVENTION OF THROMBOEMBOLIC PHENOMENA IN PATIENTS WITH FRACTURED HIPS.
    Lancet (London, England), 1964, May-23, Volume: 1, Issue:7343

    Topics: Anticoagulants; Fractures, Bone; Hip; Humans; Phenindione; Prothrombin Time; Pulmonary Embolism; Thr

1964
PHENINDIONE SENSITIVITY.
    British medical journal, 1964, Sep-19, Volume: 2, Issue:5411

    Topics: Drug Eruptions; Drug Hypersensitivity; Myocardial Infarction; Nephrotic Syndrome; Phenindione; Pulmo

1964
[MORTALITY IN FEMORAL NECK FRACTURES AND VALUE OF PREVENTIVE DICUMAROL TREATMENT].
    Nordisk medicin, 1964, Oct-17, Volume: 72

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Bronchopneumonia; Cerebral Hemorrhage; Cerebrovascular Disorder

1964
STREPTOKINASE AND PULMONARY EMBOLISM.
    Lancet (London, England), 1964, Nov-14, Volume: 2, Issue:7368

    Topics: Aminocaproates; Aminocaproic Acid; Biomedical Research; Blood Coagulation Tests; Deoxyribonuclease I

1964
IDIOSYNCRASY TO PHENINDIONE. (CASE REPORT).
    Indian heart journal, 1964, Volume: 16

    Topics: Drug Hypersensitivity; Humans; Phenindione; Pulmonary Embolism; Toxicology

1964
USE OF ANTICOAGULANTS IN THE PREVENTION OF VENOUS THROMBOEMBOLIC DISEASE IN POSTOPERATIVE PATIENTS.
    Archives of surgery (Chicago, Ill. : 1960), 1965, Volume: 90

    Topics: Acenocoumarol; Anticoagulants; Dicumarol; Drug Therapy; Heparin; Phenindione; Postoperative Complica

1965
PETECHIAE, ECCHYMOSES, AND NECROSIS OF SKIN INDUCED BY COUMARIN CONGENERS: RARE, OCCASIONALLY LETHAL COMPLICATION OF ANTICOAGULANT THERAPY.
    JAMA, 1965, May-17, Volume: 192

    Topics: Acenocoumarol; Anticoagulants; Coumarins; Dicumarol; Drug Therapy; Ecchymosis; Ethyl Biscoumacetate;

1965
ACUTE RENAL FAILURE IN PHENINDIONE SENSITIVITY.
    British medical journal, 1965, Jul-03, Volume: 2, Issue:5452

    Topics: Acute Kidney Injury; Biopsy; Drug Eruptions; Drug Therapy; Myocardial Infarction; Pathology; Phenind

1965
Prevention of venous thrombosis and pulmonary embolism in injured patients. A trial of anticoagulant prophylaxis with phenindione in middle-aged and elderly patients with fractured necks of femur.
    Lancet (London, England), 1959, Dec-05, Volume: 2, Issue:7110

    Topics: Aged; Anticoagulants; Child; Femur Neck; Humans; Infant; Middle Aged; Neck; Phenindione; Pulmonary E

1959
[Advice for patients taking oral anticoagulants (coumadin or Previscan)].
    La Revue du praticien, 2007, Apr-15, Volume: 57, Issue:7

    Topics: Administration, Oral; Anticoagulants; Feeding Behavior; Humans; International Normalized Ratio; Medi

2007
[Subdural hematoma and anticoagulant therapy].
    Neuro-Chirurgie, 1976, Volume: 22, Issue:6

    Topics: Anticoagulants; Cerebral Angiography; Coronary Disease; Craniocerebral Trauma; Dicumarol; Hematoma,

1976
[Long-term anticoagulant therapy in subjects over 75 years of age. 100 cases].
    Archives des maladies du coeur et des vaisseaux, 1977, Volume: 70, Issue:5

    Topics: Age Factors; Aged; Arteriosclerosis Obliterans; Coronary Disease; Humans; Intracranial Embolism and

1977
The prevention of deep vein thrombosis and pulmonary embolism by pharmacological methods.
    Triangle; the Sandoz journal of medical science, 1977, Volume: 16, Issue:1

    Topics: Dextrans; Heparin; Humans; Injections, Subcutaneous; Phenindione; Pulmonary Embolism; Thrombophlebit

1977
Pulmonary embolism and its prophylaxis following the Charnley total hip replacement.
    Clinical orthopaedics and related research, 1977, Issue:127

    Topics: Blood Transfusion; Early Ambulation; Heparin; Hip; Humans; Hydroxychloroquine; Infusions, Parenteral

1977
[A comparative investigation of acetylsalicyclic acid and indirect anticoagulants for the prophylaxis of venous thromboses in patients with an orthopedic-traumatologic case history (author's transl)].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1976, Volume: 114, Issue:5

    Topics: Aspirin; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteotomy; Phenindione; Postoperative C

1976
[Phenindione anticoagulant treatment during pregnancy].
    Ugeskrift for laeger, 1987, Dec-14, Volume: 149, Issue:51

    Topics: Adolescent; Adult; Drug Therapy, Combination; Female; Heparin; Humans; Infant, Newborn; Phenindione;

1987
Blood and neoplastic diseases. Thrombosis: treatment and prophylaxis.
    British medical journal, 1974, Oct-12, Volume: 4, Issue:5936

    Topics: Anticoagulants; Blood Coagulation; Catheterization; Clot Retraction; Electric Stimulation; Embolism;

1974
Diagnosis, prevention and management of thromboembolism. Nonmechanical methods of prevention.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:8

    Topics: Anticoagulants; Dextrans; Fibrinogen; Heparin; Humans; Iodine Radioisotopes; Phenindione; Postoperat

1974
The prophylactic use of anticoagulant therapy in the prevention of pulmonary emboli in one hundred consecutive spinal injury patients.
    Paraplegia, 1974, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Anticoagulants; Drug Evaluation; Humans; Male; Middle Aged; Phenindione; Pulmonar

1974
Anticoagulation for antenatal thrombo-embolic disease.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1969, Volume: 76, Issue:6

    Topics: Delivery, Obstetric; Female; Heparin; Humans; Phenindione; Postpartum Hemorrhage; Pregnancy; Pregnan

1969
Prophylactic anticoagulant therapy against pulmonary emboli in acute paraplegia.
    British medical journal, 1970, May-09, Volume: 2, Issue:5705

    Topics: Adolescent; Adult; Aged; Anticoagulants; Child; Female; Humans; Male; Middle Aged; Paraplegia; Pheni

1970
Haemorrhage-induced breast gangrene.
    The British journal of surgery, 1970, Volume: 57, Issue:9

    Topics: Aged; Breast Diseases; Female; Gangrene; Hemorrhage; Heparin; Humans; Middle Aged; Phenindione; Pulm

1970
[New case of acute kidney failure due to phenindione].
    Annales de medecine interne, 1971, Volume: 122, Issue:3

    Topics: Acute Kidney Injury; Adult; Female; Humans; Kidney Function Tests; Phenindione; Pulmonary Embolism

1971
Haemorrhagic necrosis of the breast complicating anticoagulant therapy and mitral stenosis.
    The British journal of surgery, 1971, Volume: 58, Issue:8

    Topics: Breast Diseases; Female; Hemorrhage; Humans; Middle Aged; Mitral Valve Stenosis; Necrosis; Phenindio

1971
Thromboembolism and its prevention.
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:2

    Topics: Aged; Anticoagulants; Fractures, Bone; Hip Injuries; Humans; Phenindione; Postoperative Complication

1968
Improved control of long-term anticoagulant therapy.
    British medical journal, 1968, May-11, Volume: 2, Issue:5601

    Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Female; Heart Valve Diseases; Humans; Male; Mi

1968
Factors contributing to a lowered mortality from pulmonary embolism.
    Surgery, gynecology & obstetrics, 1968, Volume: 127, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Child; Heparin; Humans; Middle Aged; Phe

1968
Prevention of recurrent pulmonary embolism.
    British medical journal, 1969, Aug-16, Volume: 3, Issue:5667

    Topics: Adolescent; Adult; Aged; Child; Female; Heparin; Humans; Male; Middle Aged; Phenindione; Phlebograph

1969
A new type of coagulation inhibitor.
    Thrombosis et diathesis haemorrhagica, 1969, Jun-15, Volume: 21, Issue:3

    Topics: Accidents, Traffic; Anemia; Blood Coagulation Disorders; Blood Coagulation Tests; Bone Marrow Examin

1969
Seasonal fluctuation in adhesive platelets during long-term anticoagulant therapy.
    British journal of haematology, 1966, Volume: 12, Issue:1

    Topics: Aged; Blood Cell Count; Blood Platelets; Carotid Artery Diseases; Coronary Disease; Humans; Male; Mi

1966
Anticoagulant prophylaxis against venous thrombosis and pulmonary embolism after injury.
    Thrombosis et diathesis haemorrhagica. Supplementum, 1966, Volume: 21

    Topics: Accidents; Bone and Bones; Humans; Phenindione; Pulmonary Embolism; Thrombophlebitis; Thrombosis; Wo

1966
[Change from athrombone to chlorathrombone].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Jul-15, Volume: 21, Issue:14

    Topics: Anticoagulants; Arrhythmias, Cardiac; Ataxia; Female; Humans; Male; Myocardial Infarction; Phenindio

1966