Page last updated: 2024-11-02

phenindione and Dermatitis Medicamentosa

phenindione has been researched along with Dermatitis Medicamentosa in 23 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Research Excerpts

ExcerptRelevanceReference
"These signs were consistent with fluindione-induced acute generalised exanthematous pustulosis."7.74[Fluindione-induced acute generalised exanthematous pustulosis confirmed by patch testing]. ( Amar, A; Chtioui, M; Cousin-Testard, F; Mahé, E; Saiag, P; Zimmermann, U, 2008)
"The authors report herein the first five cases of drug-induced hypersensitivity syndrome due to fluindione."7.71[Drug hypersensitive syndrome caused by fluindione]. ( Bédane, C; Benazahary, H; Bonnetblanc, JM; Boulinguez, S; De Vencay, P; Gauthier, ML; Le Brun, V; Loustaud-Ratti, V; Soria, P; Sparsa, A; Vidal, E, 2001)
"Fluindione (Previscan) is an oral anti-vitamin K anticoagulant, widely prescribed in France."6.42[Fluindione-induced acute exanthematous pustulosis with renal involvement]. ( Beani, JC; Bourrain, JL; Pinel, N; Reymond, JL; Thurot, C, 2003)
"Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis."5.38Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? ( Barbaud, A; Bégaud, B; Ciobanu, E; Daveluy, A; Gouraud, A; Haramburu, F; Laroche, ML; Lebrun-Vignes, B; Milpied, B; Miremont-Salamé, G; Moore, N, 2012)
"Cutaneous necrosis is a rare complication of vitamin K antagonist therapy."5.38[Skin necrosis during long-term fluindione treatment revealing protein C deficiency]. ( Alhenc-Gelas, M; Batard, ML; Cribier, B; Mazurier, I; Merklen-Djafri, C; Roth, B; Samama, MM; Tortel, MC, 2012)
"These signs were consistent with fluindione-induced acute generalised exanthematous pustulosis."3.74[Fluindione-induced acute generalised exanthematous pustulosis confirmed by patch testing]. ( Amar, A; Chtioui, M; Cousin-Testard, F; Mahé, E; Saiag, P; Zimmermann, U, 2008)
"The authors report herein the first five cases of drug-induced hypersensitivity syndrome due to fluindione."3.71[Drug hypersensitive syndrome caused by fluindione]. ( Bédane, C; Benazahary, H; Bonnetblanc, JM; Boulinguez, S; De Vencay, P; Gauthier, ML; Le Brun, V; Loustaud-Ratti, V; Soria, P; Sparsa, A; Vidal, E, 2001)
"Fluindione (Previscan) is an oral anti-vitamin K anticoagulant, widely prescribed in France."2.42[Fluindione-induced acute exanthematous pustulosis with renal involvement]. ( Beani, JC; Bourrain, JL; Pinel, N; Reymond, JL; Thurot, C, 2003)
"Fluindione was withdrawn and the ulcer healed completely within a month."1.40[Recurrent pyoderma gangrenosum-like ulcers induced by oral anticoagulants]. ( Balme, B; Ben-Said, B; Bérard, F; Debarbieux, S; Depaepe, L; Nicolas, JF; Nosbaum, A; Paret, N; Pralong, P, 2014)
"Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis."1.38Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? ( Barbaud, A; Bégaud, B; Ciobanu, E; Daveluy, A; Gouraud, A; Haramburu, F; Laroche, ML; Lebrun-Vignes, B; Milpied, B; Miremont-Salamé, G; Moore, N, 2012)
"Cutaneous necrosis is a rare complication of vitamin K antagonist therapy."1.38[Skin necrosis during long-term fluindione treatment revealing protein C deficiency]. ( Alhenc-Gelas, M; Batard, ML; Cribier, B; Mazurier, I; Merklen-Djafri, C; Roth, B; Samama, MM; Tortel, MC, 2012)
"Fluindione (Previscan) is an oral anticoagulant belonging to the vitamin K antagonist class and is very widely used in France."1.33[Hypersensitivity to fluindione (Previscan). Positive skin patch tests]. ( Frouin, E; Grange, A; Grange, F; Guillaume, JC; Roth, B; Tortel, MC, 2005)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199014 (60.87)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pralong, P1
Debarbieux, S2
Paret, N1
Balme, B1
Depaepe, L1
Nosbaum, A2
Ben-Said, B1
Nicolas, JF2
Bérard, F2
Rozières, A1
Ben Said, B1
Daveluy, A1
Milpied, B1
Barbaud, A1
Lebrun-Vignes, B1
Gouraud, A1
Laroche, ML1
Ciobanu, E1
Bégaud, B1
Moore, N1
Miremont-Salamé, G1
Haramburu, F1
Merklen-Djafri, C1
Mazurier, I1
Samama, MM1
Alhenc-Gelas, M1
Tortel, MC2
Cribier, B1
Roth, B3
Batard, ML1
EAST, EN1
BEAMISH, RE1
KINDERMANN, A1
WALLACE, DC1
PEARCE, JM1
HOLLMAN, A1
WONG, HO1
SMITH, K1
COPEMAN, PW1
PERKINS, J1
Thurot, C1
Reymond, JL1
Bourrain, JL1
Pinel, N1
Beani, JC1
Causeret, AS1
Trzeciak, MC1
Claudy, A1
Frouin, E1
Grange, A1
Grange, F1
Guillaume, JC1
Chtioui, M1
Cousin-Testard, F1
Zimmermann, U1
Amar, A1
Saiag, P1
Mahé, E1
Eldon, K1
Lindahl, F1
Sparsa, A1
Bédane, C1
Benazahary, H1
De Vencay, P1
Gauthier, ML1
Le Brun, V1
Boulinguez, S1
Loustaud-Ratti, V1
Soria, P1
Vidal, E1
Bonnetblanc, JM1
Dalley, D1
Kelleher, PR1
Larcan, A1
Bertrand, P1
Richon, J1
Calamai, M1
Paliard, P1
Moulin, G1
Motin, J1
Robillard, J1
Perrot, E1
Wright, JS1
Straub, PW1

Reviews

2 reviews available for phenindione and Dermatitis Medicamentosa

ArticleYear
[Fluindione-induced acute exanthematous pustulosis with renal involvement].
    Annales de dermatologie et de venereologie, 2003, Volume: 130, Issue:12 Pt 1

    Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Drug Eruptions; Exanthema; Humans; Male

2003
[Indications for and hazards of anticoagulant therapy].
    Schweizerische medizinische Wochenschrift, 1970, Apr-18, Volume: 100, Issue:16

    Topics: Anticoagulants; Cerebrovascular Disorders; Coumarins; Diabetic Angiopathies; Disseminated Intravascu

1970

Other Studies

21 other studies available for phenindione and Dermatitis Medicamentosa

ArticleYear
[Recurrent pyoderma gangrenosum-like ulcers induced by oral anticoagulants].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:1

    Topics: Aged; Anticoagulants; Bed Rest; Carcinoma, Basal Cell; Diagnosis, Differential; Drug Eruptions; Drug

2014
[Glycopeptide-induced cutaneous adverse reaction].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:5

    Topics: Anti-Bacterial Agents; Drug Eruptions; Eosinophilia; False Positive Reactions; Glycopeptides; Herpes

2010
Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect?
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:1

    Topics: Administration, Oral; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antic

2012
[Skin necrosis during long-term fluindione treatment revealing protein C deficiency].
    Annales de dermatologie et de venereologie, 2012, Volume: 139, Issue:3

    Topics: Abdominal Wall; Aged; Anticoagulants; Biopsy; Capillaries; Drug Eruptions; Female; Genetic Carrier S

2012
Severe sensitivity reaction (hepatitis, dermatitis and pyrexia) attributable to phenylindanedione.
    Canadian Medical Association journal, 1957, Dec-01, Volume: 77, Issue:11

    Topics: Dermatitis; Drug Eruptions; Fever; Hepatitis; Hepatitis A; Humans; Phenindione

1957
[Vascular allergid due to butalidon and hazards of its combined used with athrombon (phenylindandione)].
    Dermatologische Wochenschrift, 1961, Feb-18, Volume: 143

    Topics: Drug Eruptions; Humans; Hypersensitivity; Immune System Diseases; Phenindione; Phenylbutazone

1961
Sensitivity to phenindione ("dindevan"): report of two cases.
    The Medical journal of Australia, 1960, Jun-11, Volume: 47(1)

    Topics: Drug Eruptions; Humans; Medical Records; Phenindione

1960
Nephropathy and phenindione sensitivity.
    Lancet (London, England), 1963, May-25, Volume: 1, Issue:7291

    Topics: Drug Eruptions; Drug Hypersensitivity; Humans; Kidney Diseases; Phenindione; Uremia

1963
PHENINDIONE SENSITIVITY.
    British medical journal, 1964, Sep-19, Volume: 2, Issue:5411

    Topics: Drug Eruptions; Drug Hypersensitivity; Myocardial Infarction; Nephrotic Syndrome; Phenindione; Pulmo

1964
ACUTE RENAL FAILURE IN PHENINDIONE SENSITIVITY.
    British medical journal, 1965, Jul-03, Volume: 2, Issue:5452

    Topics: Acute Kidney Injury; Biopsy; Drug Eruptions; Drug Therapy; Myocardial Infarction; Pathology; Phenind

1965
PHENINDIONE TOXICITY.
    British medical journal, 1965, Jul-31, Volume: 2, Issue:5456

    Topics: Drug Eruptions; Drug Therapy; Phenindione; Toxicology

1965
Phenindione sensitivity.
    Lancet (London, England), 1962, Jan-20, Volume: 1, Issue:7221

    Topics: Drug Eruptions; Humans; Phenindione

1962
[A necrotic plaque on the thigh].
    Annales de dermatologie et de venereologie, 2003, Volume: 130, Issue:11

    Topics: Adult; Anticoagulants; Drug Eruptions; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; M

2003
[Hypersensitivity to fluindione (Previscan). Positive skin patch tests].
    Annales de dermatologie et de venereologie, 2005, Volume: 132, Issue:12 Pt 1

    Topics: Administration, Oral; Aged; Anticoagulants; Drug Eruptions; Drug Hypersensitivity; Edema; Female; Hu

2005
[Fluindione-induced acute generalised exanthematous pustulosis confirmed by patch testing].
    Annales de dermatologie et de venereologie, 2008, Volume: 135, Issue:4

    Topics: Aged; Drug Eruptions; Exanthema; Female; Humans; Patch Tests; Phenindione; Skin Diseases, Vesiculobu

2008
[Skin necrosis after treatment with phenindione (Dindevan)].
    Ugeskrift for laeger, 1980, Apr-07, Volume: 142, Issue:15

    Topics: Aged; Drug Eruptions; Female; Humans; Necrosis; Phenindione

1980
[Drug hypersensitive syndrome caused by fluindione].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:10 Pt 1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Drug Eruptions; Female; Humans; Male; Middle Aged; Phenindi

2001
Skin sensitivity to phenindione. Report of a case.
    The New Zealand medical journal, 1966, Volume: 65, Issue:408

    Topics: Drug Eruptions; Female; Foot Dermatoses; Hand Dermatoses; Hemorrhage; Humans; Middle Aged; Necrosis;

1966
[Necrotic and bullous skin complications of anti-vitamin K].
    La Presse medicale, 1968, May-22, Volume: 76, Issue:25

    Topics: Adult; Aged; Drug Eruptions; Ethyl Biscoumacetate; Female; Humans; Male; Necrosis; Phenindione; Post

1968
[Apropos of a case of a therapeutic complication due to phenindione].
    Lyon medical, 1967, Sep-10, Volume: 217, Issue:37

    Topics: Atrial Fibrillation; Atrial Flutter; Dermatitis, Exfoliative; Drug Eruptions; Drug Hypersensitivity;

1967
Phenindione sensitivity with leukaemoid reaction and hepato-renal damage.
    Postgraduate medical journal, 1970, Volume: 46, Issue:537

    Topics: Adult; Drug Eruptions; Female; Humans; Jaundice; Kidney Diseases; Leukemoid Reaction; Lymphadenitis;

1970