phenindione has been researched along with Cardiovascular Stroke in 76 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Excerpt | Relevance | Reference |
---|---|---|
"The catabolism of fibrinogen was studied during the first week of acute myocardial infarction in twenty-three patients and in ten control patients." | 7.65 | A study of the catabolism of fibrinogen after myocardial infarction. ( Głuszek, J; Jasiński, K; Krug, H; Smarsz, C, 1977) |
"The catabolism of fibrinogen was studied during the first week of acute myocardial infarction in twenty-three patients and in ten control patients." | 3.65 | A study of the catabolism of fibrinogen after myocardial infarction. ( Głuszek, J; Jasiński, K; Krug, H; Smarsz, C, 1977) |
" Follow-up long-term laboratory control and anticoagulant dosage were performed at one centre (the Rikshospitalet)." | 2.63 | Long-term anticoagulant therapy after myocardial infarction in women. ( Abrahamsen, AM; Bay, G; Bjerkelund, C; Borchgrevink, CF; Borgen, P; Grande, B; Helle, I; Kjörstad, H; Odegaard, A; Petersen, AM; Rörvik, T; Thorsen, R, 1968) |
" The mean phenindione dosage was 72 mg." | 2.63 | Assessment of short-anticoagulant administration after cardiac infarction. Report of the Working Party on Anticoagulant Therapy in Coronary Thrombosis to the Medical Research Council. ( , 1969) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 75 (98.68) | 18.7374 |
1990's | 1 (1.32) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
TOWNSEND, SR | 1 |
FAY, KJ | 1 |
DOWNING, JR | 1 |
LAING, R | 1 |
CAMERON, DG | 1 |
McCABE, ES | 1 |
FITTIPOLDI, J | 1 |
WARIS, E | 1 |
WRIGHT, IS | 2 |
AGER, JA | 1 |
INGRAM, GI | 1 |
PALVA, I | 1 |
KAIPAINEN, WJ | 1 |
KELLAWAY, G | 1 |
MANSON, DI | 1 |
OWREN, PA | 2 |
DUTHIE, HL | 1 |
SMITH, G | 1 |
CHOJNOWSKI, JR | 1 |
ADAMSKA-MARCINKOWSKA, H | 1 |
DOICHINOV, A | 1 |
SHALABY, ES | 1 |
ABDELSALAM, R | 1 |
CLARKSON, PM | 1 |
MCCREDIE, KB | 1 |
FLEISCHL, P | 1 |
MELTZER, LE | 1 |
PALMON, F | 1 |
FERRIGAN, M | 1 |
PEKOVER, J | 1 |
SAUER, H | 1 |
KITCHELL, JR | 1 |
PUGLIESE, F | 1 |
SILVESTRI, G | 1 |
SORG, DA | 1 |
HINES, JJ | 1 |
KESSLER, DL | 1 |
BEINSTEIN, J | 1 |
RUSSEK, HI | 1 |
SEAMAN, AJ | 2 |
GRISWOLD, HE | 2 |
REAUME, RB | 2 |
RITZMAN, LW | 1 |
COTTON, RC | 1 |
WADE, EG | 1 |
SYMONS, C | 1 |
DETOSZEGHI, A | 1 |
COOK, IJ | 1 |
HOLLMAN, A | 1 |
WONG, HO | 1 |
EASTHAM, RD | 4 |
PACKARD, JM | 1 |
RICE-WRAY, E | 1 |
PERSSON, BM | 1 |
EVENSEN, OK | 1 |
ANDERSEN, JB | 1 |
ALUSCIN, PM | 1 |
SHAROVA, IuA | 1 |
DEMIDOVA, NV | 1 |
LEAK, D | 1 |
SMITH, K | 1 |
CARTER, SA | 1 |
KRIKLER, DM | 1 |
BRENEMAN, GM | 1 |
PRIEST, EM | 1 |
O'CONNOR, WR | 1 |
THOMPSON, CE | 1 |
BAKER, LA | 1 |
Penney, JP | 1 |
Jain, VK | 1 |
Lawson, DH | 1 |
McDonald, GA | 1 |
Maragall, S | 1 |
Labal, F | 1 |
Monteagudo, J | 1 |
Goldberg, RJ | 1 |
Gore, JM | 1 |
Dalen, JE | 1 |
Singer, RB | 1 |
Paul, H | 1 |
Krug, H | 1 |
Głuszek, J | 1 |
Smarsz, C | 1 |
Jasiński, K | 1 |
Nigro, G | 1 |
Comi, LI | 1 |
Limongelli, FM | 1 |
Giugliano, MA | 1 |
Inglese, FP | 1 |
Politano, L | 1 |
Rado, Iu | 1 |
Chikvashvili, DI | 1 |
Douglas, AS | 1 |
Colwell, L | 1 |
Rose, G | 1 |
Harpur, JE | 1 |
Conner, WT | 1 |
Hamilton, M | 1 |
Kellett, RJ | 1 |
Galbraith, HJ | 1 |
Murray, JJ | 1 |
Swallow, JH | 1 |
Rose, GA | 1 |
Drapkin, A | 1 |
Merskey, C | 1 |
Fiedler, H | 1 |
Thiele, G | 1 |
Borchgrevink, CF | 1 |
Bjerkelund, C | 1 |
Abrahamsen, AM | 1 |
Bay, G | 1 |
Borgen, P | 1 |
Grande, B | 1 |
Helle, I | 1 |
Kjörstad, H | 1 |
Petersen, AM | 1 |
Rörvik, T | 1 |
Thorsen, R | 1 |
Odegaard, A | 1 |
Ritland, S | 1 |
Lygren, T | 1 |
Straub, PW | 1 |
Mehrotra, TN | 1 |
Ritzmann, L | 1 |
Delaveirre, PH | 1 |
Hureau, J | 1 |
Grivaux, M | 1 |
Chretien, J | 1 |
Etienne, JP | 1 |
Schubert, W | 1 |
Neilson, GH | 1 |
Seldon, WA | 1 |
Mackinnon, J | 1 |
Dabels, J | 1 |
Konrad, H | 1 |
Schulz, K | 1 |
Kubicek, F | 1 |
Praschl, E | 1 |
Bagchi, AL | 1 |
Ghosh, BP | 1 |
Marx, R | 1 |
Gormsen, J | 1 |
Heine, H | 1 |
Schmidt, H | 1 |
Mach, H | 1 |
Jaruszewski, H | 1 |
Churin, VD | 1 |
Bykov, II | 1 |
Lechner, K | 1 |
Avis, PR | 1 |
Hume, R | 1 |
Geoghegan, M | 1 |
Hutton, I | 1 |
Reid, DS | 1 |
Linton, AL | 1 |
Lange, LS | 1 |
Geidel, H | 1 |
Helbig, A | 1 |
6 reviews available for phenindione and Cardiovascular Stroke
Article | Year |
---|---|
CURRENT MYTHS AND REALITIES IN ANTICOAGULANT THERAPY FOR CORONARY HEART DISEASE.
Topics: Angina Pectoris; Anticoagulants; Coronary Artery Disease; Coronary Disease; Dicumarol; Heparin; Huma | 1964 |
[Anticoagulant therapy].
Topics: Anticoagulants; Coumarins; Embolism; Heart Valve Prosthesis; Heparin; Humans; Intracranial Embolism | 1984 |
The role of anticoagulant therapy in acute myocardial infarction.
Topics: Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Female; Fibri | 1984 |
[Indications for and hazards of anticoagulant therapy].
Topics: Anticoagulants; Cerebrovascular Disorders; Coumarins; Diabetic Angiopathies; Disseminated Intravascu | 1970 |
A critical evaluation of anticoagulant therapy.
Topics: Anticoagulants; Blood Coagulation Tests; Cerebral Hemorrhage; Cerebrovascular Disorders; Coumarins; | 1969 |
Anticoagulants and coronary heart disease.
Topics: Age Factors; Anticoagulants; Arrhythmias, Cardiac; Coumarins; Female; Heart Failure; Humans; Male; M | 1969 |
10 trials available for phenindione and Cardiovascular Stroke
Article | Year |
---|---|
The role of anticoagulant therapy in acute myocardial infarction.
Topics: Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Female; Fibri | 1984 |
Long-term mortality in patients after a British trial of anticoagulants in acute myocardial infarction.
Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Follow | 1993 |
Twenty year follow up of patients in the Medical Research Council trial of anticoagulants in acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; England; Female; Follow-Up Studies; Humans; | 1987 |
Controlled trial of early mobilisation and discharge from hospital in uncomplicated myocardial infarction.
Topics: Alanine Transaminase; Anticoagulants; Arrhythmias, Cardiac; Aspartate Aminotransferases; Electrocard | 1971 |
Anticoagulant therapy after acute myocardial infarction. Relation of therapeutic benefit to patient's age, sex, and severity of infarction.
Topics: Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetes Com | 1972 |
Long-term anticoagulant therapy after myocardial infarction in women.
Topics: Aged; Anticoagulants; Blood Coagulation Tests; Clinical Trials as Topic; Dicumarol; Female; Follow-U | 1968 |
Comparison of efficacy of 3 and 12 months' anticoagulant therapy after myocardial infarction. A controlled clinical trial.
Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Cerebral Hemorrhage; Clinical Trials as Topic; | 1969 |
Long-term anticoagulant prophylaxis after myocardial infarction.
Topics: Aftercare; Anticoagulants; Female; Hospitalization; Humans; Long-Term Care; Male; Middle Aged; Myoca | 1969 |
Assessment of short-anticoagulant administration after cardiac infarction. Report of the Working Party on Anticoagulant Therapy in Coronary Thrombosis to the Medical Research Council.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myoca | 1969 |
Propranolol in angina pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Drug Synergism; Hemorrhage; Humans; Myocardial Infarction | 1969 |
61 other studies available for phenindione and Cardiovascular Stroke
Article | Year |
---|---|
Phenylindanedione: a useful anticoagulant.
Topics: Anticoagulants; Humans; Myocardial Infarction; Phenindione; Thrombophlebitis | 1953 |
Current status of use of phenylindanedione: case report.
Topics: Myocardial Infarction; Phenindione; Thromboembolism | 1953 |
[Experience with phenindione in clinical practice].
Topics: Hemostatics; Humans; Myocardial Infarction; Phenindione; Prothrombin | 1954 |
Present status of anticoagulant therapy in the treatment of myocardial infarction; the use and misuse of anticoagulants; an evaluation of new anticoagulants, their indications and dosage.
Topics: Anticoagulants; Cardiovascular Diseases; Coumarins; Heparin; Humans; Myocardial Infarction; Phenindi | 1955 |
Agranulocytosis during phenindione therapy.
Topics: Agranulocytosis; Humans; Myocardial Infarction; Phenindione | 1957 |
[Prolonged phenindione therapy of ambulant cases].
Topics: Humans; Myocardial Infarction; Phenindione | 1957 |
Clinical evaluation of miradon.
Topics: Coronary Disease; Humans; Myocardial Infarction; Phenindione; Thrombosis | 1958 |
Treatment of cardiac infarction with oral anticoagulants.
Topics: Anticoagulants; Ethyl Biscoumacetate; Humans; Infarction; Myocardial Infarction; Phenindione | 1958 |
Long term treatment with anticoagulants in coronary artery disease.
Topics: Angina Pectoris; Anticoagulants; Coronary Artery Disease; Coronary Disease; Dicumarol; Humans; Long- | 1958 |
Failure of phenindione to prevent intravascular clotting.
Topics: Anticoagulants; Humans; Myocardial Infarction; Phenindione; Thrombosis | 1960 |
[CLINICAL OBSERVATIONS ON THE ANTICOAGULANT EFFECT OF FENHYDREN].
Topics: Anticoagulants; Myocardial Infarction; Phenindione | 1963 |
[ANTICOAGULANTS IN THE TREATMENT OF MYOCARDIAL INFARCT].
Topics: Anticoagulants; Coumarins; Heparin; Humans; Myocardial Infarction; Phenindione; Thromboembolism; War | 1963 |
THE EFFECT OF 2, 6-BIS (DIETHANOLAMINO)-4,8-DIPIPERIDINE (PERSANTIN) ON THE PROTHROMBIN TIME.
Topics: Angina Pectoris; Dipyridamole; Heart Failure; Humans; Myocardial Infarction; Pharmacology; Phenindio | 1963 |
ALLERGIC PERICARDITIS.
Topics: Angioedema; Asthma; Diagnosis, Differential; Electrocardiography; Humans; Meperidine; Myocardial Inf | 1964 |
PROTHROMBIN LEVELS AND FATALITY RATES IN ACUTE MYOCARDIAL INFARCTION.
Topics: Cardiovascular Diseases; Dicumarol; Geriatrics; Hematologic Tests; Heparin; Middle Aged; Mortality; | 1964 |
[ANTICOAGULANT THERAPY OF MYOCARDIAL INFARCT].
Topics: Angina Pectoris; Anticoagulants; Cardiac Complexes, Premature; Heart Failure; Heparin; Humans; Myoca | 1963 |
HYPOPROTHROMBINEMIA AND UNSUSPECTED MALIGNANCY.
Topics: Adenocarcinoma; Anticoagulants; Carcinoma; Carcinoma, Transitional Cell; Coronary Disease; Diabetes | 1964 |
OUTPATIENT ANTICOAGULATION: A PROBLEM IN LONG-TERM MANAGEMENT.
Topics: Blood Coagulation Tests; Coronary Disease; Dicumarol; Geriatrics; Intracranial Embolism; Intracrania | 1964 |
PROPHYLACTIC ANTICOAGULANT THERAPY FOR CORONARY ARTERY DISEASE. A SEVEN-YEAR CONTROLLED STUDY.
Topics: Anticoagulants; Biomedical Research; Coronary Artery Disease; Coronary Disease; Humans; Myocardial I | 1964 |
EFFECT OF SUDDEN WITHDRAWAL OF LONG-TERM ANTICOAGULANT THERAPY ON THE HEPARIN RESISTANCE AND PLASMA FIBRINOGEN LEVEL.
Topics: Anticoagulants; Blood Coagulation Disorders; Blood Coagulation Tests; Electrocardiography; Fibrinoge | 1964 |
EFFECT OF ETHYL CHLOROPHENOXYISOBUTYRATE WITH OR WITHOUT ANDROSTERONE ON PLATELET STICKINESS.
Topics: Androsterone; Biomedical Research; Blood Platelets; Butyrates; Cholesterol; Clofibrate; Drug Therapy | 1964 |
PHENINDIONE SENSITIVITY.
Topics: Drug Eruptions; Drug Hypersensitivity; Myocardial Infarction; Nephrotic Syndrome; Phenindione; Pulmo | 1964 |
ATTEMPTED REDUCTION OF ADHESIVE PLATELETS AFTER CARDIAC INFARCTION.
Topics: Adhesives; Blood Cell Count; Blood Platelets; Carotid Artery Thrombosis; Coronary Disease; Geriatric | 1964 |
CURRENT THERAPY OF ACUTE MYOCARDIAL INFARCTION.
Topics: Anterior Wall Myocardial Infarction; Anticoagulants; Arrhythmias, Cardiac; Diet; Diet Therapy; Dimen | 1964 |
AN ASSESSMENT OF LONG-TERM ANTICOAGULANT ADMINISTRATION AFTER CARDIAC INFARCTION. SECOND REPORT OF THE WORKING PARTY ON ANTICOAGULANT THERAPY IN CORONARY THROMBOSIS TO THE MEDICAL RESEARCH COUNCIL.
Topics: Anticoagulants; Biomedical Research; Coronary Thrombosis; Electrocardiography; Humans; Infarction; M | 1964 |
[MORTALITY IN FEMORAL NECK FRACTURES AND VALUE OF PREVENTIVE DICUMAROL TREATMENT].
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Bronchopneumonia; Cerebral Hemorrhage; Cerebrovascular Disorder | 1964 |
[COMPLICATIONS IN TROMBANTIN TREATMENT, WITH SPECIAL REFERENCE TO INTERSTITIAL NEPHRITIS].
Topics: Aspartate Aminotransferases; Humans; Myocardial Infarction; Nephritis; Nephritis, Interstitial; Phen | 1964 |
[EXPERIENCE WITH THE USE OF INDANDIONE ANTICOAGULANTS IN MYOCARDIAL INFARCT AND STENOCARDIA].
Topics: Angina Pectoris; Anticoagulants; Drug Therapy; Myocardial Infarction; Phenindione | 1964 |
THE ROLE OF ANTICOAGULANT THERAPY IN THE TREATMENT OF MYOCARDIAL INFARCTION.
Topics: Anticoagulants; Cardiovascular Diseases; Dicumarol; Drug Therapy; Geriatrics; Heparin; Myocardial In | 1965 |
ACUTE RENAL FAILURE IN PHENINDIONE SENSITIVITY.
Topics: Acute Kidney Injury; Biopsy; Drug Eruptions; Drug Therapy; Myocardial Infarction; Pathology; Phenind | 1965 |
POTENTIATION OF THE EFFECT OF ORALLY ADMINISTERED ANTICOAGULANTS BY PHENYRAMIDOL HYDROCHLORIDE.
Topics: Analgesics; Analgesics, Non-Narcotic; Anticoagulants; Antipyretics; Atrial Fibrillation; Blood Coagu | 1965 |
PHENINDIONE TOXICITY.
Topics: Drug Hypersensitivity; Drug Therapy; Myocardial Infarction; Phenindione; Toxicology | 1965 |
Experience with phenylindanedione in the management of acute myocardial infarction.
Topics: Anterior Wall Myocardial Infarction; Cardiovascular Diseases; Disease Management; Humans; Myocardial | 1955 |
Experience with the new anticoagulant phenylindanedione in acute myocardial infarction; preliminary report of 50 cases.
Topics: Anterior Wall Myocardial Infarction; Anticoagulants; Cardiovascular Diseases; Humans; Myocardial Inf | 1952 |
Diplopia and oral anticoagulants.
Topics: Diplopia; Humans; Male; Middle Aged; Myocardial Infarction; Phenindione | 1967 |
Control of long-term anticoagulant therapy.
Topics: Anticoagulants; Embolism; Humans; Hypertension, Pulmonary; Myocardial Infarction; Phenindione; Renal | 1967 |
Critical assessment of the role of anticoagulant in acute myocardial infarction, specially in the tropics.
Topics: Heparin; Humans; India; Myocardial Infarction; Phenindione | 1979 |
A study of the catabolism of fibrinogen after myocardial infarction.
Topics: Acute Disease; Fibrinogen; Half-Life; Heparin; Humans; Myocardial Infarction; Phenindione; Time Fact | 1977 |
[Results of 473 years of anticoagulant therapy].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Middle Aged; Myocardial Infarction; Phenindione; | 1977 |
The efficacy of long-term oral anticoagulant therapy and its laboratory assessment.
Topics: Adult; Blood Coagulation; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Myocardial Infarc | 1975 |
[Effect of long-term anticoagulant and antithrombocytic therapy on the size of intracavitary thrombus and the incidence of thromboembolic complications in patients with acute myocardial infarction].
Topics: Aspirin; Heart Diseases; Humans; Myocardial Infarction; Phenindione; Thromboembolism; Thrombosis; Ti | 1989 |
[Myocardial infarct and the shoulder-hand syndrome].
Topics: Adult; Age Factors; Aged; Aspirin; Benzyl Compounds; Coumarins; Exercise Therapy; Humans; Middle Age | 1972 |
Phenindione-induced neuropathy.
Topics: Electric Stimulation; Heparin; Humans; Male; Median Nerve; Myocardial Infarction; Peripheral Nervous | 1967 |
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; In | 1973 |
[Influence of long-term anticoagulant treatment on reinfarction, mortality and rehabilitation of patients with myocardial infarct. 4-year-observation ambulatory surveillance of infarction].
Topics: Aged; Anticoagulants; Benzyl Compounds; Coumarins; Female; Hematoma; Hematuria; Humans; Indenes; Ket | 1972 |
[On long term treatment of heart infarction with anticoagulants].
Topics: Aged; Anticoagulants; Ethyl Biscoumacetate; Hemorrhage; Humans; Long-Term Care; Middle Aged; Myocard | 1968 |
[Clinical experiences with anticoagulant long term treatment of predominantly cardiologic patients].
Topics: Acenocoumarol; Adult; Aged; Angina Pectoris; Anticoagulants; Coronary Disease; Coumarins; Female; He | 1968 |
Report on long term therapy with anticoagulants.
Topics: Arteriosclerosis Obliterans; Humans; Myocardial Infarction; Phenindione; Warfarin | 1964 |
Effect of anticoagulant therapy on platelet adhesiveness in cases of acute myocardial infarction.
Topics: Diabetic Angiopathies; Heparin; Humans; Myocardial Infarction; Phenindione; Platelet Adhesiveness | 1972 |
[Anticoagulant therapy].
Topics: Adult; Aged; Anticoagulants; Coumarins; Female; Heparin; Humans; Male; Middle Aged; Myocardial Infar | 1970 |
[Thrombolytic treatment in acute myocardial infarct].
Topics: Acute Disease; Humans; Myocardial Infarction; Phenindione; Streptokinase | 1971 |
[Anticoagulant therapy and prophylaxis in arterial vascular diseases].
Topics: Angina Pectoris; Anticoagulants; Arteries; Coumarins; Hemorrhage; Humans; Myocardial Infarction; Phe | 1971 |
Improved control of long-term anticoagulant therapy.
Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Female; Heart Valve Diseases; Humans; Male; Mi | 1968 |
[On the effectiveness of anticoagulant therapy in acute myocardial infarct].
Topics: Adult; Aged; Female; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Phenindione | 1968 |
[Prevention of a second myocardial infarct by way of prolonged use of anticoagulants with indirect action].
Topics: Adult; Aged; Anticoagulants; Ethyl Biscoumacetate; Female; Humans; Male; Methods; Middle Aged; Myoca | 1968 |
A new type of coagulation inhibitor.
Topics: Accidents, Traffic; Anemia; Blood Coagulation Disorders; Blood Coagulation Tests; Bone Marrow Examin | 1969 |
Seasonal fluctuation in adhesive platelets during long-term anticoagulant therapy.
Topics: Aged; Blood Cell Count; Blood Platelets; Carotid Artery Diseases; Coronary Disease; Humans; Male; Mi | 1966 |
Fibrinolytic activity in patients receiving long-term anticoagulants for myocardial infarction.
Topics: Anxiety Disorders; Fibrinolysis; Humans; Male; Middle Aged; Myocardial Infarction; Phenindione | 1966 |
Control of anticoagulant therapy in hospital.
Topics: Anticoagulants; Blood Coagulation Tests; Humans; Myocardial Infarction; Phenindione; Thrombosis | 1966 |
Lower limb palsies with hypoprothrombinaemia.
Topics: Female; Femoral Nerve; Humans; Hypoprothrombinemias; Leg; Male; Middle Aged; Myocardial Infarction; | 1966 |
[Change from athrombone to chlorathrombone].
Topics: Anticoagulants; Arrhythmias, Cardiac; Ataxia; Female; Humans; Male; Myocardial Infarction; Phenindio | 1966 |