phenindione has been researched along with Body Weight in 4 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present multicentre study, we sought to develop and validate a model including genetic and non-genetic factors to predict the daily fluindione dose requirement in elderly patients in whom VKA dosing is challenging." | 5.40 | A model predicting fluindione dose requirement in elderly inpatients including genotypes, body weight, and amiodarone. ( Andro, M; Berndt, C; Duverlie, C; Emmerich, J; Golmard, JL; Gouin-Thibault, I; Lacut, K; Le Gal, G; Loriot, MA; Mahé, I; Moreau, C; Pautas, E; Peyron, I; Siguret, V, 2014) |
| "We reviewed the English-language literature via PubMed and Scopus using the search terms VKA, warfarin, acenocoumarol, phenprocoumon, fluindione, AND body weight." | 4.91 | Effect of Body Weight on Dose of Vitamin K Antagonists. ( Sakaan, S; Sands, CW; Self, TH; Wallace, JL, 2015) |
| " The pharmacodynamic response was best described by an indirect action model with S-acenocoumarol concentrations and fluindione concentrations as the only exposure predictors of the INR response." | 2.77 | A pharmacokinetic-pharmacodynamic model for predicting the impact of CYP2C9 and VKORC1 polymorphisms on fluindione and acenocoumarol during induction therapy. ( Becquemont, L; Delavenne, X; Diquet, B; Jaillon, P; Lebot, M; Robert, A; Rousseau, A; Tod, M; Verstuyft, C, 2012) |
| " In the present multicentre study, we sought to develop and validate a model including genetic and non-genetic factors to predict the daily fluindione dose requirement in elderly patients in whom VKA dosing is challenging." | 1.40 | A model predicting fluindione dose requirement in elderly inpatients including genotypes, body weight, and amiodarone. ( Andro, M; Berndt, C; Duverlie, C; Emmerich, J; Golmard, JL; Gouin-Thibault, I; Lacut, K; Le Gal, G; Loriot, MA; Mahé, I; Moreau, C; Pautas, E; Peyron, I; Siguret, V, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreau, C | 1 |
| Pautas, E | 1 |
| Duverlie, C | 1 |
| Berndt, C | 1 |
| Andro, M | 1 |
| Mahé, I | 1 |
| Emmerich, J | 1 |
| Lacut, K | 1 |
| Le Gal, G | 1 |
| Peyron, I | 1 |
| Gouin-Thibault, I | 1 |
| Golmard, JL | 1 |
| Loriot, MA | 1 |
| Siguret, V | 1 |
| Self, TH | 1 |
| Wallace, JL | 1 |
| Sakaan, S | 1 |
| Sands, CW | 1 |
| Verstuyft, C | 1 |
| Delavenne, X | 1 |
| Rousseau, A | 1 |
| Robert, A | 1 |
| Tod, M | 1 |
| Diquet, B | 1 |
| Lebot, M | 1 |
| Jaillon, P | 1 |
| Becquemont, L | 1 |
| Elias, DJ | 1 |
| Johns, BE | 1 |
1 review available for phenindione and Body Weight
| Article | Year |
|---|---|
Effect of Body Weight on Dose of Vitamin K Antagonists.
Topics: Acenocoumarol; Anticoagulants; Body Weight; Comorbidity; Drug Dosage Calculations; Humans; Obesity; | 2015 |
1 trial available for phenindione and Body Weight
| Article | Year |
|---|---|
A pharmacokinetic-pharmacodynamic model for predicting the impact of CYP2C9 and VKORC1 polymorphisms on fluindione and acenocoumarol during induction therapy.
Topics: Acenocoumarol; Adult; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Body Weight; Cross-Over Studies | 2012 |
2 other studies available for phenindione and Body Weight
| Article | Year |
|---|---|
A model predicting fluindione dose requirement in elderly inpatients including genotypes, body weight, and amiodarone.
Topics: Aged; Aged, 80 and over; Amiodarone; Body Weight; Drug Dosage Calculations; Female; Gene-Environment | 2014 |
Response of rats to chronic ingestion of diphacinone.
Topics: Animals; Body Weight; Diet; Eating; Enzymes; Phenindione; Prothrombin Time; Rats; Rats, Inbred Strai | 1981 |