Page last updated: 2024-11-02

phenindione and Amyloidosis

phenindione has been researched along with Amyloidosis in 1 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

Research Excerpts

ExcerptRelevanceReference
"Nine patients with multiple myeloma (n=6) or AL amyloidosis (n=3), including 6 prospective patients, taking fluindione (n=8) or warfarin (n=1), were studied for a total of 10 cycles."9.12Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis. ( Amoura, Z; Ankri, A; Aymard, G; Berenbaum, F; Cacoub, P; Choquet, S; Costedoat-Chalumeau, N; Hulot, JS; Leblond, V; Lechat, P; Mariette, X; Piette, JC; Sellam, J; Trad, S; Vignes, BL, 2007)
"Nine patients with multiple myeloma (n=6) or AL amyloidosis (n=3), including 6 prospective patients, taking fluindione (n=8) or warfarin (n=1), were studied for a total of 10 cycles."5.12Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis. ( Amoura, Z; Ankri, A; Aymard, G; Berenbaum, F; Cacoub, P; Choquet, S; Costedoat-Chalumeau, N; Hulot, JS; Leblond, V; Lechat, P; Mariette, X; Piette, JC; Sellam, J; Trad, S; Vignes, BL, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sellam, J1
Costedoat-Chalumeau, N1
Amoura, Z1
Aymard, G1
Choquet, S1
Trad, S1
Vignes, BL1
Hulot, JS1
Berenbaum, F1
Lechat, P1
Cacoub, P1
Ankri, A1
Mariette, X1
Leblond, V1
Piette, JC1

Trials

1 trial available for phenindione and Amyloidosis

ArticleYear
Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis.
    Joint bone spine, 2007, Volume: 74, Issue:5

    Topics: Aged; Amyloidosis; Anticoagulants; Blood Coagulation; Creatinine; Dexamethasone; Drug Synergism; Fem

2007