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phenindione and Allergy, Drug

phenindione has been researched along with Allergy, Drug in 36 studies

Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

Research Excerpts

ExcerptRelevanceReference
"This rare side effect is a reminder of the importance of biological monitoring in the first weeks following the introduction of fluindione and key diagnostic elements and therapeutic aspects of iatrogenic agranulocytosis."7.83[Agranulocytosis related to fluindione: A case report]. ( Armengol, G; Benhamou, Y; Buchonnet, G; Cailleux-Talbot, N; Lévesque, H; Massy, N; Ngo, S; Sauvêtre, G, 2016)
"Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis."5.38Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? ( Barbaud, A; Bégaud, B; Ciobanu, E; Daveluy, A; Gouraud, A; Haramburu, F; Laroche, ML; Lebrun-Vignes, B; Milpied, B; Miremont-Salamé, G; Moore, N, 2012)
"Fluindione is a vitamin K antagonist that is commonly prescribed for the treatment of cardiovascular disease and venous thromboembolism in France."5.33Acute immuno-allergic interstitial nephritis caused by fluindione. ( Abou Ayache, R; Bauwens, M; Belmouaz, S; Bridoux, F; Desport, E; Goujon, JM; Mignot, A; Thierry, A; Touchard, G, 2006)
"This rare side effect is a reminder of the importance of biological monitoring in the first weeks following the introduction of fluindione and key diagnostic elements and therapeutic aspects of iatrogenic agranulocytosis."3.83[Agranulocytosis related to fluindione: A case report]. ( Armengol, G; Benhamou, Y; Buchonnet, G; Cailleux-Talbot, N; Lévesque, H; Massy, N; Ngo, S; Sauvêtre, G, 2016)
"Fluindione has been linked to cases of acute generalised exanthematic pustulosis."2.46Immunoallergic adverse effects of fluindione. ( , 2010)
"Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis."1.38Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? ( Barbaud, A; Bégaud, B; Ciobanu, E; Daveluy, A; Gouraud, A; Haramburu, F; Laroche, ML; Lebrun-Vignes, B; Milpied, B; Miremont-Salamé, G; Moore, N, 2012)
"Phenindione was presented to T-cells via two pathways: first, bound directly to major histocompatibility complex and second, bound to a processed peptide."1.33Characterization of the T-cell response in a patient with phenindione hypersensitivity. ( Berry, NG; Chamberlain, PJ; Farrell, J; Hopkins, JE; Naisbitt, DJ; Park, BK; Pirmohamed, M, 2005)
"Fluindione (Previscan) is an oral anticoagulant belonging to the vitamin K antagonist class and is very widely used in France."1.33[Hypersensitivity to fluindione (Previscan). Positive skin patch tests]. ( Frouin, E; Grange, A; Grange, F; Guillaume, JC; Roth, B; Tortel, MC, 2005)
"Fluindione is a vitamin K antagonist that is commonly prescribed for the treatment of cardiovascular disease and venous thromboembolism in France."1.33Acute immuno-allergic interstitial nephritis caused by fluindione. ( Abou Ayache, R; Bauwens, M; Belmouaz, S; Bridoux, F; Desport, E; Goujon, JM; Mignot, A; Thierry, A; Touchard, G, 2006)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199028 (77.78)18.7374
1990's0 (0.00)18.2507
2000's4 (11.11)29.6817
2010's4 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ngo, S1
Benhamou, Y1
Armengol, G1
Sauvêtre, G1
Cailleux-Talbot, N1
Massy, N1
Buchonnet, G1
Lévesque, H1
Reynaud, F1
Giraud, P1
Cisterne, JM1
Verdier, D1
Kouchakipour, Z1
Hermelin, A1
Modesto-Segonds, A1
Bagheri, H1
Pourrat, J1
Daveluy, A1
Milpied, B1
Barbaud, A1
Lebrun-Vignes, B1
Gouraud, A1
Laroche, ML1
Ciobanu, E1
Bégaud, B1
Moore, N1
Miremont-Salamé, G1
Haramburu, F1
Cam, G1
Kwetcheu, AT1
Vigneau, C1
Siohan, P1
Queffeulou, G1
Gatault, P1
Laruelle, E1
Crémault, A1
Le Cacheux, P1
Rioux-Leclercq, N1
Renaudineau, E1
PEARCE, JM1
GALEA, EG1
YOUNG, LN1
BELL, JR1
GOULSTON, K1
BAKER, SB1
WILLIAMS, RT1
KERWIN, AJ1
HOLLMAN, A1
WONG, HO1
BUSCHMANN, O1
WILLICH, E1
FOLLETT, SA1
BHARGAVA, RK1
DHOOT, BM1
KRIKLER, DM1
Naisbitt, DJ1
Farrell, J1
Chamberlain, PJ1
Hopkins, JE1
Berry, NG1
Pirmohamed, M1
Park, BK1
Frouin, E1
Roth, B1
Grange, A1
Grange, F1
Tortel, MC1
Guillaume, JC1
Belmouaz, S1
Desport, E1
Abou Ayache, R1
Thierry, A1
Mignot, A1
Bauwens, M1
Goujon, JM1
Bridoux, F1
Touchard, G1
Spriggs, AI1
Jerrome, DW1
Kleinknecht, D1
Kanfer, A1
Morel-Maroger, L1
Méry, JP1
Horellou, MF1
Feiss, P1
Voultoury, JC1
Gay, R1
Bundgaard, H1
Chevet, D1
Garré, M1
Thomas, R1
Ramée, MP1
Goasguen, J1
Alquier, P1
Varet, B1
Gluckman, E1
Reyes, F1
Basch, A1
Dreyfus, B1
Brunetaud, JM1
Coudoux, P1
Geoffroy, H1
Lancaster-Smith, MJ1
Paliard, P1
Moulin, G1
Motin, J1
Robillard, J1
Perrot, E1
Manigand, G1
Auzépy, P1
Lardy, C1
Levene, GM1
Opolon, P1
Cartron, J1
Chicot, D1
Caroli, J1
Gupta, MC1
Kumar, S1
Tyagi, SP1
Srivastava, SS1
Chassagnon, C1
Drevet, M1
Joseph, JY1
Nicholls, MG1
Heale, WF1
Tanser, AR1
Keat, EC1
Mohamed, SD1

Reviews

3 reviews available for phenindione and Allergy, Drug

ArticleYear
Immunoallergic adverse effects of fluindione.
    Prescrire international, 2010, Volume: 19, Issue:110

    Topics: Acute Kidney Injury; Anticoagulants; Drug Hypersensitivity; Humans; Liver Failure, Acute; Phenindion

2010
Immunologically mediated drug-induced acute renal failure.
    Contributions to nephrology, 1978, Volume: 10

    Topics: Acute Kidney Injury; Antigens; Basement Membrane; Drug Hypersensitivity; Glafenine; Glomerulonephrit

1978
Drug reactions. V. Cutaneous reactions to anticoagulants.
    The British journal of dermatology, 1969, Volume: 81, Issue:3

    Topics: Alopecia; Anticoagulants; Blister; Coumarins; Drug Hypersensitivity; Erythema; Hemorrhage; Humans; M

1969

Other Studies

33 other studies available for phenindione and Allergy, Drug

ArticleYear
[Agranulocytosis related to fluindione: A case report].
    La Revue de medecine interne, 2016, Volume: 37, Issue:1

    Topics: Aged; Agranulocytosis; Anticoagulants; Chemotherapy-Induced Febrile Neutropenia; Drug Hypersensitivi

2016
[Acute immuno-allergic interstitial nephritis after treatment with fluindione. Seven cases].
    Nephrologie & therapeutique, 2009, Volume: 5, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anticoagulants; Drug Hypersensitivity; Female; Humans;

2009
Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect?
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:1

    Topics: Administration, Oral; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antic

2012
Acute and chronic nephropathy induced by fluindione must be addressed.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anticoagulants; Coumarins; Drug Hypersensitivit

2012
Nephropathy and phenindione sensitivity.
    Lancet (London, England), 1963, May-25, Volume: 1, Issue:7291

    Topics: Drug Eruptions; Drug Hypersensitivity; Humans; Kidney Diseases; Phenindione; Uremia

1963
Fatal nephropathy due to phenindione sensitivity.
    Lancet (London, England), 1963, Apr-27, Volume: 1, Issue:7287

    Topics: Drug Hypersensitivity; Humans; Kidney Diseases; Phenindione

1963
Sensitivity to phenindione ("Dindevan").
    The Medical journal of Australia, 1962, Nov-24, Volume: 2

    Topics: Drug Hypersensitivity; Humans; Phenindione

1962
Acute interstitial nephritis due to drug sensitivity.
    British medical journal, 1963, Jun-22, Volume: 1, Issue:5346

    Topics: Drug Hypersensitivity; Drug Tolerance; Humans; Nephritis; Nephritis, Interstitial; Phenindione

1963
FATAL MYOCARDITIS DUE TO SENSITIVITY TO PHENINDIONE.
    Canadian Medical Association journal, 1964, Jun-20, Volume: 90

    Topics: Coronary Disease; Drug Hypersensitivity; Drug Therapy; Myocarditis; Nephritis; Nephritis, Interstiti

1964
PHENINDIONE SENSITIVITY.
    British medical journal, 1964, Sep-19, Volume: 2, Issue:5411

    Topics: Drug Eruptions; Drug Hypersensitivity; Myocardial Infarction; Nephrotic Syndrome; Phenindione; Pulmo

1964
[PHENINDIONE NEPHROPATHY].
    Deutsche medizinische Wochenschrift (1946), 1964, Aug-28, Volume: 89

    Topics: Drug Hypersensitivity; Kidney Diseases; Phenindione; Toxicology

1964
OLIGURIA DUE TO A HYPERSENSITIVITY REACTION TO PHENINDIONE.
    Nursing times, 1964, Oct-30, Volume: 60

    Topics: Acute Kidney Injury; Anuria; Drug Hypersensitivity; Fibula; Fractures, Bone; Kidney; Kidneys, Artifi

1964
IDIOSYNCRASY TO PHENINDIONE. (CASE REPORT).
    Indian heart journal, 1964, Volume: 16

    Topics: Drug Hypersensitivity; Humans; Phenindione; Pulmonary Embolism; Toxicology

1964
PHENINDIONE TOXICITY.
    The Central African journal of medicine, 1965, Volume: 11

    Topics: Drug Hypersensitivity; Drug Therapy; Myocardial Infarction; Phenindione; Toxicology

1965
Characterization of the T-cell response in a patient with phenindione hypersensitivity.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:3

    Topics: Drug Hypersensitivity; Female; Humans; Interferon-gamma; Interleukin-5; Lymphocyte Activation; Middl

2005
[Hypersensitivity to fluindione (Previscan). Positive skin patch tests].
    Annales de dermatologie et de venereologie, 2005, Volume: 132, Issue:12 Pt 1

    Topics: Administration, Oral; Aged; Anticoagulants; Drug Eruptions; Drug Hypersensitivity; Edema; Female; Hu

2005
Acute immuno-allergic interstitial nephritis caused by fluindione.
    Clinical nephrology, 2006, Volume: 66, Issue:6

    Topics: Aged; Anticoagulants; Biopsy; Diagnosis, Differential; Drug Hypersensitivity; Follow-Up Studies; Hum

2006
Electron-microscopy of Türk cells.
    British journal of haematology, 1967, Volume: 13, Issue:5

    Topics: Adolescent; Cytoplasm; Drug Hypersensitivity; Female; Humans; Lymphocytes; Male; Measles; Microscopy

1967
[Acute renal insufficiency caused by phenyl-indane-dione. Apropos of 1 case].
    Annales de l'anesthesiologie francaise, 1978, Volume: 19, Issue:11-12

    Topics: Acute Kidney Injury; Drug Hypersensitivity; Female; Humans; Middle Aged; Phenindione; Renal Dialysis

1978
Identification and quantitation of a 3-benzylidenephthalide contaminant of phenindione tablets and its characterization as a potentially immunogenic substance.
    Acta pharmaceutica Suecica, 1975, Volume: 12, Issue:4

    Topics: Antigens; Benzylidene Compounds; Drug Contamination; Drug Hypersensitivity; Phenindione; Tablets

1975
[Letter: Phenylindanedione-induced nephropathies. Value of the leukocyte migration inhibition test].
    La Nouvelle presse medicale, 1976, Feb-28, Volume: 5, Issue:9

    Topics: Acute Kidney Injury; Adult; Aged; Cell Migration Inhibition; Child; Drug Hypersensitivity; Female; H

1976
[Acute drug cytopenia. Apropos of 11 cases].
    Annales de medecine interne, 1971, Volume: 122, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Anemia; Antithyroid Agents; Blood Transfusion; Bone Marro

1971
The choice of an oral anticoagulant.
    Drug and therapeutics bulletin, 1972, Mar-31, Volume: 10, Issue:7

    Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Dicumarol; Drug Hypersensitivity; Ethyl Biscoum

1972
[Iatrogenic pathology in hematology].
    Maroc medical, 1972, Volume: 52, Issue:555

    Topics: Agranulocytosis; Alkylating Agents; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Anti

1972
Delayed reaction to phenindione.
    Lancet (London, England), 1969, Nov-08, Volume: 2, Issue:7628

    Topics: Aged; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Male; Phenindione

1969
[Apropos of a case of a therapeutic complication due to phenindione].
    Lyon medical, 1967, Sep-10, Volume: 217, Issue:37

    Topics: Atrial Fibrillation; Atrial Flutter; Dermatitis, Exfoliative; Drug Eruptions; Drug Hypersensitivity;

1967
[A case of serious intolerance during treatment by phenindione: preventive measures to be taken].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Dec-14, Volume: 44, Issue:52

    Topics: Acute Kidney Injury; Agranulocytosis; Anuria; Bone Marrow; Chemical and Drug Induced Liver Injury; D

1968
[Application of the lymphoblastic transformation test (LTT) to the diagnosis of drug-induced hepatitis].
    La Presse medicale, 1969, Dec-20, Volume: 77, Issue:54

    Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans;

1969
Stomatitis, agranulocytosis and hepatits due to phenindione sensitivity.
    Journal of the Indian Medical Association, 1974, Nov-16, Volume: 63, Issue:10

    Topics: Adult; Agranulocytosis; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Male;

1974
[Allergy to Pendione].
    Journal de medecine de Lyon, 1971, May-20, Volume: 52, Issue:120

    Topics: Aged; Drug Hypersensitivity; Female; Humans; Phenindione

1971
Phenindione sensitivity and acute renal failure.
    The New Zealand medical journal, 1970, Volume: 71, Issue:455

    Topics: Acute Kidney Injury; Albuminuria; Drug Hypersensitivity; Humans; Kidney Papillary Necrosis; Kidney T

1970
Phenindione-induced haemorrhagic ulcerative colitis.
    British medical journal, 1966, Mar-05, Volume: 1, Issue:5487

    Topics: Colitis, Ulcerative; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Phenindione

1966
Sensitivity reaction to phenindione with urticaria, hepatitis, and pancytopenia.
    British medical journal, 1965, Dec-18, Volume: 2, Issue:5476

    Topics: Agranulocytosis; Anemia, Aplastic; Angioedema; Chemical and Drug Induced Liver Injury; Drug Hypersen

1965