phenindione has been researched along with Allergy, Drug in 36 studies
Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Excerpt | Relevance | Reference |
---|---|---|
"This rare side effect is a reminder of the importance of biological monitoring in the first weeks following the introduction of fluindione and key diagnostic elements and therapeutic aspects of iatrogenic agranulocytosis." | 7.83 | [Agranulocytosis related to fluindione: A case report]. ( Armengol, G; Benhamou, Y; Buchonnet, G; Cailleux-Talbot, N; Lévesque, H; Massy, N; Ngo, S; Sauvêtre, G, 2016) |
"Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis." | 5.38 | Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? ( Barbaud, A; Bégaud, B; Ciobanu, E; Daveluy, A; Gouraud, A; Haramburu, F; Laroche, ML; Lebrun-Vignes, B; Milpied, B; Miremont-Salamé, G; Moore, N, 2012) |
"Fluindione is a vitamin K antagonist that is commonly prescribed for the treatment of cardiovascular disease and venous thromboembolism in France." | 5.33 | Acute immuno-allergic interstitial nephritis caused by fluindione. ( Abou Ayache, R; Bauwens, M; Belmouaz, S; Bridoux, F; Desport, E; Goujon, JM; Mignot, A; Thierry, A; Touchard, G, 2006) |
"This rare side effect is a reminder of the importance of biological monitoring in the first weeks following the introduction of fluindione and key diagnostic elements and therapeutic aspects of iatrogenic agranulocytosis." | 3.83 | [Agranulocytosis related to fluindione: A case report]. ( Armengol, G; Benhamou, Y; Buchonnet, G; Cailleux-Talbot, N; Lévesque, H; Massy, N; Ngo, S; Sauvêtre, G, 2016) |
"Fluindione has been linked to cases of acute generalised exanthematic pustulosis." | 2.46 | Immunoallergic adverse effects of fluindione. ( , 2010) |
"Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis." | 1.38 | Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? ( Barbaud, A; Bégaud, B; Ciobanu, E; Daveluy, A; Gouraud, A; Haramburu, F; Laroche, ML; Lebrun-Vignes, B; Milpied, B; Miremont-Salamé, G; Moore, N, 2012) |
"Phenindione was presented to T-cells via two pathways: first, bound directly to major histocompatibility complex and second, bound to a processed peptide." | 1.33 | Characterization of the T-cell response in a patient with phenindione hypersensitivity. ( Berry, NG; Chamberlain, PJ; Farrell, J; Hopkins, JE; Naisbitt, DJ; Park, BK; Pirmohamed, M, 2005) |
"Fluindione (Previscan) is an oral anticoagulant belonging to the vitamin K antagonist class and is very widely used in France." | 1.33 | [Hypersensitivity to fluindione (Previscan). Positive skin patch tests]. ( Frouin, E; Grange, A; Grange, F; Guillaume, JC; Roth, B; Tortel, MC, 2005) |
"Fluindione is a vitamin K antagonist that is commonly prescribed for the treatment of cardiovascular disease and venous thromboembolism in France." | 1.33 | Acute immuno-allergic interstitial nephritis caused by fluindione. ( Abou Ayache, R; Bauwens, M; Belmouaz, S; Bridoux, F; Desport, E; Goujon, JM; Mignot, A; Thierry, A; Touchard, G, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (77.78) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (11.11) | 29.6817 |
2010's | 4 (11.11) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ngo, S | 1 |
Benhamou, Y | 1 |
Armengol, G | 1 |
Sauvêtre, G | 1 |
Cailleux-Talbot, N | 1 |
Massy, N | 1 |
Buchonnet, G | 1 |
Lévesque, H | 1 |
Reynaud, F | 1 |
Giraud, P | 1 |
Cisterne, JM | 1 |
Verdier, D | 1 |
Kouchakipour, Z | 1 |
Hermelin, A | 1 |
Modesto-Segonds, A | 1 |
Bagheri, H | 1 |
Pourrat, J | 1 |
Daveluy, A | 1 |
Milpied, B | 1 |
Barbaud, A | 1 |
Lebrun-Vignes, B | 1 |
Gouraud, A | 1 |
Laroche, ML | 1 |
Ciobanu, E | 1 |
Bégaud, B | 1 |
Moore, N | 1 |
Miremont-Salamé, G | 1 |
Haramburu, F | 1 |
Cam, G | 1 |
Kwetcheu, AT | 1 |
Vigneau, C | 1 |
Siohan, P | 1 |
Queffeulou, G | 1 |
Gatault, P | 1 |
Laruelle, E | 1 |
Crémault, A | 1 |
Le Cacheux, P | 1 |
Rioux-Leclercq, N | 1 |
Renaudineau, E | 1 |
PEARCE, JM | 1 |
GALEA, EG | 1 |
YOUNG, LN | 1 |
BELL, JR | 1 |
GOULSTON, K | 1 |
BAKER, SB | 1 |
WILLIAMS, RT | 1 |
KERWIN, AJ | 1 |
HOLLMAN, A | 1 |
WONG, HO | 1 |
BUSCHMANN, O | 1 |
WILLICH, E | 1 |
FOLLETT, SA | 1 |
BHARGAVA, RK | 1 |
DHOOT, BM | 1 |
KRIKLER, DM | 1 |
Naisbitt, DJ | 1 |
Farrell, J | 1 |
Chamberlain, PJ | 1 |
Hopkins, JE | 1 |
Berry, NG | 1 |
Pirmohamed, M | 1 |
Park, BK | 1 |
Frouin, E | 1 |
Roth, B | 1 |
Grange, A | 1 |
Grange, F | 1 |
Tortel, MC | 1 |
Guillaume, JC | 1 |
Belmouaz, S | 1 |
Desport, E | 1 |
Abou Ayache, R | 1 |
Thierry, A | 1 |
Mignot, A | 1 |
Bauwens, M | 1 |
Goujon, JM | 1 |
Bridoux, F | 1 |
Touchard, G | 1 |
Spriggs, AI | 1 |
Jerrome, DW | 1 |
Kleinknecht, D | 1 |
Kanfer, A | 1 |
Morel-Maroger, L | 1 |
Méry, JP | 1 |
Horellou, MF | 1 |
Feiss, P | 1 |
Voultoury, JC | 1 |
Gay, R | 1 |
Bundgaard, H | 1 |
Chevet, D | 1 |
Garré, M | 1 |
Thomas, R | 1 |
Ramée, MP | 1 |
Goasguen, J | 1 |
Alquier, P | 1 |
Varet, B | 1 |
Gluckman, E | 1 |
Reyes, F | 1 |
Basch, A | 1 |
Dreyfus, B | 1 |
Brunetaud, JM | 1 |
Coudoux, P | 1 |
Geoffroy, H | 1 |
Lancaster-Smith, MJ | 1 |
Paliard, P | 1 |
Moulin, G | 1 |
Motin, J | 1 |
Robillard, J | 1 |
Perrot, E | 1 |
Manigand, G | 1 |
Auzépy, P | 1 |
Lardy, C | 1 |
Levene, GM | 1 |
Opolon, P | 1 |
Cartron, J | 1 |
Chicot, D | 1 |
Caroli, J | 1 |
Gupta, MC | 1 |
Kumar, S | 1 |
Tyagi, SP | 1 |
Srivastava, SS | 1 |
Chassagnon, C | 1 |
Drevet, M | 1 |
Joseph, JY | 1 |
Nicholls, MG | 1 |
Heale, WF | 1 |
Tanser, AR | 1 |
Keat, EC | 1 |
Mohamed, SD | 1 |
3 reviews available for phenindione and Allergy, Drug
Article | Year |
---|---|
Immunoallergic adverse effects of fluindione.
Topics: Acute Kidney Injury; Anticoagulants; Drug Hypersensitivity; Humans; Liver Failure, Acute; Phenindion | 2010 |
Immunologically mediated drug-induced acute renal failure.
Topics: Acute Kidney Injury; Antigens; Basement Membrane; Drug Hypersensitivity; Glafenine; Glomerulonephrit | 1978 |
Drug reactions. V. Cutaneous reactions to anticoagulants.
Topics: Alopecia; Anticoagulants; Blister; Coumarins; Drug Hypersensitivity; Erythema; Hemorrhage; Humans; M | 1969 |
33 other studies available for phenindione and Allergy, Drug
Article | Year |
---|---|
[Agranulocytosis related to fluindione: A case report].
Topics: Aged; Agranulocytosis; Anticoagulants; Chemotherapy-Induced Febrile Neutropenia; Drug Hypersensitivi | 2016 |
[Acute immuno-allergic interstitial nephritis after treatment with fluindione. Seven cases].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anticoagulants; Drug Hypersensitivity; Female; Humans; | 2009 |
Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect?
Topics: Administration, Oral; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antic | 2012 |
Acute and chronic nephropathy induced by fluindione must be addressed.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anticoagulants; Coumarins; Drug Hypersensitivit | 2012 |
Nephropathy and phenindione sensitivity.
Topics: Drug Eruptions; Drug Hypersensitivity; Humans; Kidney Diseases; Phenindione; Uremia | 1963 |
Fatal nephropathy due to phenindione sensitivity.
Topics: Drug Hypersensitivity; Humans; Kidney Diseases; Phenindione | 1963 |
Sensitivity to phenindione ("Dindevan").
Topics: Drug Hypersensitivity; Humans; Phenindione | 1962 |
Acute interstitial nephritis due to drug sensitivity.
Topics: Drug Hypersensitivity; Drug Tolerance; Humans; Nephritis; Nephritis, Interstitial; Phenindione | 1963 |
FATAL MYOCARDITIS DUE TO SENSITIVITY TO PHENINDIONE.
Topics: Coronary Disease; Drug Hypersensitivity; Drug Therapy; Myocarditis; Nephritis; Nephritis, Interstiti | 1964 |
PHENINDIONE SENSITIVITY.
Topics: Drug Eruptions; Drug Hypersensitivity; Myocardial Infarction; Nephrotic Syndrome; Phenindione; Pulmo | 1964 |
[PHENINDIONE NEPHROPATHY].
Topics: Drug Hypersensitivity; Kidney Diseases; Phenindione; Toxicology | 1964 |
OLIGURIA DUE TO A HYPERSENSITIVITY REACTION TO PHENINDIONE.
Topics: Acute Kidney Injury; Anuria; Drug Hypersensitivity; Fibula; Fractures, Bone; Kidney; Kidneys, Artifi | 1964 |
IDIOSYNCRASY TO PHENINDIONE. (CASE REPORT).
Topics: Drug Hypersensitivity; Humans; Phenindione; Pulmonary Embolism; Toxicology | 1964 |
PHENINDIONE TOXICITY.
Topics: Drug Hypersensitivity; Drug Therapy; Myocardial Infarction; Phenindione; Toxicology | 1965 |
Characterization of the T-cell response in a patient with phenindione hypersensitivity.
Topics: Drug Hypersensitivity; Female; Humans; Interferon-gamma; Interleukin-5; Lymphocyte Activation; Middl | 2005 |
[Hypersensitivity to fluindione (Previscan). Positive skin patch tests].
Topics: Administration, Oral; Aged; Anticoagulants; Drug Eruptions; Drug Hypersensitivity; Edema; Female; Hu | 2005 |
Acute immuno-allergic interstitial nephritis caused by fluindione.
Topics: Aged; Anticoagulants; Biopsy; Diagnosis, Differential; Drug Hypersensitivity; Follow-Up Studies; Hum | 2006 |
Electron-microscopy of Türk cells.
Topics: Adolescent; Cytoplasm; Drug Hypersensitivity; Female; Humans; Lymphocytes; Male; Measles; Microscopy | 1967 |
[Acute renal insufficiency caused by phenyl-indane-dione. Apropos of 1 case].
Topics: Acute Kidney Injury; Drug Hypersensitivity; Female; Humans; Middle Aged; Phenindione; Renal Dialysis | 1978 |
Identification and quantitation of a 3-benzylidenephthalide contaminant of phenindione tablets and its characterization as a potentially immunogenic substance.
Topics: Antigens; Benzylidene Compounds; Drug Contamination; Drug Hypersensitivity; Phenindione; Tablets | 1975 |
[Letter: Phenylindanedione-induced nephropathies. Value of the leukocyte migration inhibition test].
Topics: Acute Kidney Injury; Adult; Aged; Cell Migration Inhibition; Child; Drug Hypersensitivity; Female; H | 1976 |
[Acute drug cytopenia. Apropos of 11 cases].
Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Anemia; Antithyroid Agents; Blood Transfusion; Bone Marro | 1971 |
The choice of an oral anticoagulant.
Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Dicumarol; Drug Hypersensitivity; Ethyl Biscoum | 1972 |
[Iatrogenic pathology in hematology].
Topics: Agranulocytosis; Alkylating Agents; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Anti | 1972 |
Delayed reaction to phenindione.
Topics: Aged; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Male; Phenindione | 1969 |
[Apropos of a case of a therapeutic complication due to phenindione].
Topics: Atrial Fibrillation; Atrial Flutter; Dermatitis, Exfoliative; Drug Eruptions; Drug Hypersensitivity; | 1967 |
[A case of serious intolerance during treatment by phenindione: preventive measures to be taken].
Topics: Acute Kidney Injury; Agranulocytosis; Anuria; Bone Marrow; Chemical and Drug Induced Liver Injury; D | 1968 |
[Application of the lymphoblastic transformation test (LTT) to the diagnosis of drug-induced hepatitis].
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; | 1969 |
Stomatitis, agranulocytosis and hepatits due to phenindione sensitivity.
Topics: Adult; Agranulocytosis; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Male; | 1974 |
[Allergy to Pendione].
Topics: Aged; Drug Hypersensitivity; Female; Humans; Phenindione | 1971 |
Phenindione sensitivity and acute renal failure.
Topics: Acute Kidney Injury; Albuminuria; Drug Hypersensitivity; Humans; Kidney Papillary Necrosis; Kidney T | 1970 |
Phenindione-induced haemorrhagic ulcerative colitis.
Topics: Colitis, Ulcerative; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Phenindione | 1966 |
Sensitivity reaction to phenindione with urticaria, hepatitis, and pancytopenia.
Topics: Agranulocytosis; Anemia, Aplastic; Angioedema; Chemical and Drug Induced Liver Injury; Drug Hypersen | 1965 |