phenformin has been researched along with Neoplasms in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S; Chen, Y; Fu, L; He, G; Liu, B | 1 |
| Altinoz, MA; Ozpinar, A | 1 |
| Agostinelli, E; Battistini, L; Cairoli, S; Canettieri, G; Capalbo, C; Coni, S; De Smaele, E; Di Magno, L; Di Marcotullio, L; Di Pastena, F; Giannini, G; Goffredo, BM; Infante, P; Iorio, E; Macone, A; Manni, S; Maroder, M; Moretti, M; Nicoletti, C; Petroni, M; Sambucci, M | 1 |
| Jang, H; Kang, JH; Kim, HY; Kim, SY; Lee, H; Lee, JS; Lee, SH; Park, JB; Song, J; Woo, SM | 1 |
| Bollag, WB; Jung, J | 1 |
| Ando, A; Baba, Y; Ebara, S; Hara, T; Kitazawa, S; Satomi, Y; Soga, T | 1 |
| Antonia, RJ; Baldwin, AS | 1 |
| A Marchal, J; Boulaiz, H; Carrillo, E; Domínguez-Martín, A; García Rubiño, ME; Ruiz Alcalá, G | 1 |
| Bayraktar, EC; Birsoy, K; Chen, WW; Clish, CB; Lorbeer, FK; Possemato, R; Sabatini, DM; Thiru, P; Wang, T; Yucel, B | 1 |
| Blagih, J; Coelho, PP; Griss, T; Jones, RG; Vincent, EE; Viollet, B | 1 |
| Birman, E; Blouin, MJ; Gravel, SP; Hulea, L; Pollak, M; St-Pierre, J; Toban, N; Topisirovic, I; Zakikhani, M; Zhao, Y | 1 |
| Choi, EK; Jang, SJ; Jo, SY; Jung, CL; Lee, C; Mun, H; Oh, JH; Suh, YA | 1 |
| Gan, B; Liu, X | 1 |
| Furuno, A; Park, HR; Saito, S; Sakamoto, A; Sakurai, J; Shin-Ya, K; Tomida, A; Tsuruo, T | 1 |
| Berstein, LM | 1 |
| Anisimov, VN; Semenchenko, AV; Yashin, AI | 1 |
| Kreisberg, RA | 1 |
| Bastl, CP; Narins, RG; Rudnick, MR | 1 |
| Dilman, VM | 1 |
| Harken, AH | 1 |
| Bershteĭn, LM; Bobrov, IuF; Dil'man, VM; Kovaleva, IG; Tsyrlina, EV | 1 |
6 review(s) available for phenformin and Neoplasms
| Article | Year |
|---|---|
Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors.
Topics: Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Protein Kinase Inhibitors; Signal Transduction | 2022 |
Oxamate targeting aggressive cancers with special emphasis to brain tumors.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glycolysis; Humans; L-Lactate Dehydrogenase; Mitochondria; Neoplasms; Oxamic Acid; Phenformin; Radiation Tolerance; Reactive Oxygen Species; Temozolomide | 2022 |
Phenformin as an Anticancer Agent: Challenges and Prospects.
Topics: Animals; Antineoplastic Agents; Diabetes Mellitus, Type 2; Humans; Models, Biological; Neoplasms; Phenformin; Risk Factors | 2019 |
Modern approach to metabolic rehabilitation of cancer patients: biguanides (phenformin and metformin) and beyond.
Topics: Diet Therapy; Exercise Therapy; Humans; Hypoglycemic Agents; Metformin; Neoplasms; Phenformin | 2010 |
Lactate homeostasis and lactic acidosis.
Topics: Acidosis; Animals; Diabetic Ketoacidosis; Dichloroacetic Acid; Ethanol; Homeostasis; Humans; Hypoglycemia; Kidney; Lactates; Liver; Liver Diseases; Neoplasms; Phenformin; Renal Dialysis; Salicylates; Seizures; Vasodilator Agents | 1980 |
Lactic acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Catecholamines; Diabetic Ketoacidosis; Energy Metabolism; Ethanol; Humans; Lactates; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Phenformin; Pyruvates; Shock; Thiamine Deficiency | 1976 |
15 other study(ies) available for phenformin and Neoplasms
| Article | Year |
|---|---|
Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Topics: Animals; Antineoplastic Agents; Co-Repressor Proteins; Hedgehog Proteins; Humans; Hypoglycemic Agents; Mice; Neoplasms; Phenformin | 2020 |
Targeting Oxidative Phosphorylation Reverses Drug Resistance in Cancer Cells by Blocking Autophagy Recycling.
Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Agents; Autophagy; Drug Resistance, Neoplasm; Drug Synergism; Electron Transport Complex I; Gossypol; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phenformin; Xenograft Model Antitumor Assays | 2020 |
Phenformin: AMP(K)ed for Potential Repurposing.
Topics: Adenosine Monophosphate; Drug Repositioning; Humans; Hypoglycemic Agents; Neoplasms; Phenformin | 2021 |
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors.
Topics: Antineoplastic Agents; Azepines; Benzodiazepines; Citric Acid Cycle; CRISPR-Cas Systems; Dehydroepiandrosterone; Fumarates; Gene Knockout Techniques; Glucosephosphate Dehydrogenase; Glycolysis; HCT116 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Metabolomics; Mitochondria; Mutation; Neoplasms; Oxygen Consumption; Phenformin; Phosphoglycerate Dehydrogenase; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Succinate Dehydrogenase; Succinic Acid; Triazoles | 2017 |
IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells.
Topics: A549 Cells; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Apoptosis; Cells, Cultured; Cytokines; HeLa Cells; Humans; I-kappa B Kinase; Mice, Knockout; Neoplasms; Phenformin; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Threonine | 2018 |
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides.
Topics: Adenosine Triphosphate; Animals; Biguanides; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Culture Media; DNA, Mitochondrial; Electron Transport Complex I; Glucose; Humans; Hypoglycemic Agents; Male; Mice; Mitochondria; Molecular Typing; Mutation; Neoplasm Transplantation; Neoplasms; Oxidative Phosphorylation; Phenformin; RNA Interference; Saccharomyces cerevisiae Proteins; Xenograft Model Antitumor Assays | 2014 |
Differential effects of AMPK agonists on cell growth and metabolism.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Glucose; HCT116 Cells; HEK293 Cells; Humans; Hypoglycemic Agents; Lactic Acid; Metformin; Mice; Neoplasms; Phenformin; Pyrones; Ribonucleotides; Sodium Salicylate; Thiophenes | 2015 |
Serine deprivation enhances antineoplastic activity of biguanides.
Topics: Animals; Biguanides; Cell Line, Tumor; Glycolysis; Humans; Metformin; Mice; Neoplasms; Oxidative Phosphorylation; Phenformin; Serine; Xenograft Model Antitumor Assays | 2014 |
Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo.
Topics: A549 Cells; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxyglucose; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Humans; MAP Kinase Signaling System; Mice; Mutation; Neoplasm Metastasis; Neoplasms; Phenformin; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2016 |
lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1.
Topics: AMP-Activated Protein Kinases; Cell Death; Cell Line, Tumor; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; HEK293 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Neoplasms; Phenformin; RNA, Long Noncoding; Subcellular Fractions; TOR Serine-Threonine Kinases; Transcription Factors | 2016 |
Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation.
Topics: Activating Transcription Factor 4; Cell Death; Cell Survival; DNA-Binding Proteins; Gene Expression Profiling; Genes, Reporter; Genomics; Glucose; Humans; Hypoglycemic Agents; Macrolides; Neoplasms; Oligosaccharides; Phenformin; Plasmids; Protein Denaturation; Protein Folding; Regulatory Factor X Transcription Factors; Transcription Factors; Transfection; X-Box Binding Protein 1 | 2009 |
Insulin and longevity: antidiabetic biguanides as geroprotectors.
Topics: Aging; Animals; Buformin; Female; Humans; Hypoglycemic Agents; Insulin; Longevity; Mice; Neoplasms; Phenformin; Rats; Survival Rate | 2003 |
The kidney in health and disease: XVIII: lactic acidosis and the elevated anion gap (II).
Topics: Acidosis; Bicarbonates; Blood Chemical Analysis; Diabetes Mellitus; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hypoxia; Lactates; Neoplasms; Phenformin; Pyruvate Dehydrogenase Complex; Water-Electrolyte Imbalance | 1980 |
Ageing, metabolic immunodepression and carcinogenesis.
Topics: Adult; Aged; Aging; Cell Transformation, Neoplastic; Cholesterol; Clofibrate; Coronary Disease; Diabetes Mellitus; Energy Metabolism; Fatty Acids, Nonesterified; Female; Humans; Hypothalamo-Hypophyseal System; Immunity, Cellular; Immunologic Deficiency Syndromes; Insulin; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Neoplasms; Phenformin; Pregnancy; Triglycerides | 1978 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; Cholesterol; Clofibrate; Colonic Neoplasms; Endocrine System Diseases; Fatty Acids; Female; Growth Hormone; Humans; Insulin; Lipoproteins; Lung Neoplasms; Middle Aged; Neoplasms; Phenformin; Phenytoin; Phospholipids; Triglycerides; Uric Acid; Uterine Neoplasms | 1975 |