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Page last updated: 2024-08-18

phenformin and Malignant Melanoma

phenformin has been researched along with Malignant Melanoma in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Dotto, GP; Huang, M; Kim, SH; Liu, C; Pérez-Lorenzo, R; Wu, X; Zheng, B; Zhou, Q1
Boros, LG; Collins, TQ; D'Agostino, DP; Hitendra, P; Meuillet, EJ; Somlyai, G1
Kim, SH; Li, M; Pasca di Magliano, M; Swanson, KD; Trousil, S; Zhang, Y; Zheng, B1
Beaulieu, D; Nijhawan, RI1
Carelli, V; Ciarrocchi, A; Dallaglio, K; Gallo, C; Maresca, A; Pistoni, M; Tondelli, G; Torricelli, F1
Bosenberg, MW; Cantley, LC; Del Guzzo, C; Ito, K; Lee, JH; McMahon, M; Perez-Lorenzo, R; Shen, CH; Yuan, P; Zheng, B1
Lilla, C; Livingstone, E; Roesch, A; Schadendorf, D; Swann, S1
Albini, A; Argenziano, G; Ciarrocchi, A; Dallaglio, K; Dominici, M; Grisendi, G; Longo, C; Petrachi, T; Romagnani, A1
Cantley, LC; Chen, S; Manstein, D; Merghoub, T; Mu, C; Ran, Y; Rosen, N; Shakuntala, T; Shaw, FM; Trousil, S; Yao, Z; Zheng, B; Zippin, JH1
Anichini, A; Bersani, I; Cleris, L; Formelli, F; Hardie, GD; Molla, A; Mustard, KJ; Petti, C; Sensi, M; Vegetti, C1

Reviews

1 review(s) available for phenformin and Malignant Melanoma

ArticleYear
Structural homologies between phenformin, lipitor and gleevec aim the same metabolic oncotarget in leukemia and melanoma.
    Oncotarget, 2017, Jul-25, Volume: 8, Issue:30

    Topics: Atorvastatin; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanoma; Metformin; Phenformin

2017

Other Studies

9 other study(ies) available for phenformin and Malignant Melanoma

ArticleYear
Phenformin Promotes Keratinocyte Differentiation via the Calcineurin/NFAT Pathway.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:1

    Topics: Animals; Calcineurin; Cell Differentiation; Humans; Hypoglycemic Agents; Keratinocytes; Melanoma; Mice; Neoplasms, Experimental; Nitrofurans; Phenformin; Signal Transduction; Skin; Skin Neoplasms

2021
Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:8

    Topics: Animals; Cell Line, Tumor; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Hypoglycemic Agents; Immunohistochemistry; Immunotherapy; Melanoma; Mice; Myeloid-Derived Suppressor Cells; Neoplasms, Experimental; Phenformin; Programmed Cell Death 1 Receptor; Real-Time Polymerase Chain Reaction; RNA, Neoplasm; Skin Neoplasms; Tumor Cells, Cultured

2017
Cells to Surgery Quiz: February 2018.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:2

    Topics: Humans; Keratinocytes; Melanoma; Myeloid-Derived Suppressor Cells; Nitric Oxide Synthase Type II; Phenformin; Skin; Skin Neoplasms; Tumor Microenvironment; Vascular Endothelial Growth Factor A

2018
Exploring metabolic reprogramming in melanoma via acquired resistance to the oxidative phosphorylation inhibitor phenformin.
    Melanoma research, 2020, Volume: 30, Issue:1

    Topics: Cellular Reprogramming; Humans; Hypoglycemic Agents; Melanoma; Phenformin

2020
Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-05, Volume: 110, Issue:45

    Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; DNA-Binding Proteins; Immunohistochemistry; Indoles; Jumonji Domain-Containing Histone Demethylases; Melanoma; Mice; Mutation, Missense; Phenformin; Proto-Oncogene Proteins B-raf; Sulfonamides

2013
Combining BRAF(V) (600E) inhibition with modulators of the mitochondrial bioenergy metabolism to overcome drug resistance in metastatic melanoma.
    Experimental dermatology, 2015, Volume: 24, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzodiazepines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Hydrazines; Imidazoles; Indoles; Melanoma; Metformin; Mitochondria; Oxidative Phosphorylation; Oximes; Phenformin; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sulfonamides; Vemurafenib

2015
Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Aldehyde Dehydrogenase; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Energy Metabolism; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Metformin; Microphthalmia-Associated Transcription Factor; Neoplasm Invasiveness; Neoplastic Stem Cells; Phenformin; Phenotype; Skin Neoplasms; Spheroids, Cellular; Time Factors; Transfection

2017
Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:5

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Indazoles; Melanoma; Mutation; Neurofibromin 1; Oxygen Consumption; Phenformin; Piperazines

2017
AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway.
    Melanoma research, 2012, Volume: 22, Issue:5

    Topics: Amino Acid Sequence; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Enzyme Activators; Female; HEK293 Cells; Humans; Immunohistochemistry; Melanoma; Mice; Mice, Nude; Molecular Sequence Data; Phenformin; Phosphorylation; Ribonucleotides; Signal Transduction; Skin Neoplasms

2012