phenformin has been researched along with Carcinoma, Non-Small Cell Lung in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Akel, M; Doraiswamy, A; Gilleran, J; Jia, D; Langenfeld, J; Mondal, A; Patel, Y; Peng, Y; Roberge, J; Zoltowski, H | 1 |
| Choi, YJ; Im, JH; Kang, KW; Kim, S; Kim, SJ; Kim, SK; Kim, WK; Kwon, SW; Lee, JY | 1 |
| Cai, H; Chen, R; Guan, Q; Guo, Z; He, J; Li, X; Liu, H; Song, K; Wang, X; Yan, H; Zheng, W | 1 |
| Kang, JH; Kim, SY; Lee, JS; Lee, S; Lee, SH; Seo, J; Song, J | 1 |
| Wang, J; Xia, S; Zhu, Z | 1 |
| Baltazar, F; Granja, S; Le Floch, R; Marchiq, I; Moura, CS; Pouysségur, J | 1 |
| Abt, E; Dubinett, SM; Fishbein, MC; Magyar, C; McMickle, R; Momcilovic, M; Seki, A; Shackelford, DB; Simko, SA; Stout, DB; Walser, TC | 1 |
| Hong, KM; Jang, H; Kang, JH; Kim, SY; Lee, C; Lee, JS; Lee, SH; Nam, B; Seong, TW; Son, J | 1 |
| Abt, E; Czernin, J; Fishbein, MC; Gerken, L; Leblanc, M; Mischel, PS; Seki, A; Shackelford, DB; Shaw, RJ; Vasquez, DS; Wei, L | 1 |
9 other study(ies) available for phenformin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Bone morphogenetic protein inhibitors and mitochondria targeting agents synergistically induce apoptosis-inducing factor (AIF) caspase-independent cell death in lung cancer cells.
Topics: AMP-Activated Protein Kinases; Apoptosis; Apoptosis Inducing Factor; Bone Morphogenetic Proteins; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Death; Humans; Lung; Lung Neoplasms; Mitochondria; Phenformin; Protein Serine-Threonine Kinases | 2022 |
Enhanced Sensitivity of Nonsmall Cell Lung Cancer with Acquired Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors to Phenformin: The Roles of a Metabolic Shift to Oxidative Phosphorylation and Redox Balance.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Hypoglycemic Agents; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oxidation-Reduction; Oxidative Phosphorylation; Phenformin; Protein Kinase Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line; Databases, Genetic; Drug Repositioning; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Metformin; Phenformin; Protein Interaction Maps; Sample Size; Statistics as Topic; Transcriptome | 2017 |
Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Gossypol; Heterografts; Humans; Irinotecan; Mice; Mitochondria; Oxidative Phosphorylation; Phenformin | 2018 |
Synergistic effect of phenformin in non-small cell lung cancer (NSCLC) ionizing radiation treatment.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA-Binding Proteins; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Phenformin; Radiation-Sensitizing Agents; Transcription Factors | 2015 |
Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antineoplastic Agents; Basigin; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Female; Gene Knockdown Techniques; Glycolysis; Humans; Lactic Acid; Lung Neoplasms; Metformin; Mice, Nude; Monocarboxylic Acid Transporters; Muscle Proteins; Phenformin; Protein Serine-Threonine Kinases; Protein Transport; Symporters; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoxazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Humans; Immunohistochemistry; Lung Neoplasms; Mice; Phenformin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Pyrimidines; Stress, Physiological | 2015 |
Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion.
Topics: Action Potentials; Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytosol; Female; Gossypol; Humans; Lung Neoplasms; Malates; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP; Neoplasm Transplantation; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Phenformin; RNA, Small Interfering | 2016 |
LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cells, Cultured; Eukaryotic Initiation Factor-2; Humans; Hypoglycemic Agents; Lung Neoplasms; Mice; Mice, Knockout; Mitochondria; Mutation; Phenformin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Suppressor Protein p53 | 2013 |