Page last updated: 2024-08-18

phenformin and Breast Neoplasms

phenformin has been researched along with Breast Neoplasms in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Aguilar-Mahecha, A; Ahn, R; Avizonis, D; Basik, M; Cepeda Cañedo, E; Chabot, C; Dankner, M; Goulet, ML; Hébert, S; Im, YK; Kleinman, CL; Kuasne, H; La Selva, R; Lebeau, B; Lewis, K; Lin, R; Martínez, C; Najyb, O; Nguyen, A; Park, M; Petrecca, K; Pollak, M; Sabourin, V; Santos Martínez, N; Savage, P; Siegel, PM; St-Pierre, J; Topisirovic, I; Totten, SP; Ursini-Siegel, J; Witcher, M1
Aleidi, SM; Alsalamat, HA; Bardaweel, SK; Bashatwah, RM1
Albini, A; Bertolini, F; Calleri, A; Dallaglio, K; Gregato, G; Labanca, V; Mancuso, P; Noonan, DM; Orecchioni, S; Reggiani, F; Talarico, G1
Liu, C; Liu, Z; Ren, L; Wang, S; Xia, T; Zha, X1
Alessi, DR; Appleyard, MV; Bray, SE; Coates, PJ; Fleming, S; Kernohan, NM; Murray, KE; Thompson, AM; Wullschleger, S1
Pezzino, V; Purrello, F; Trischitta, V; Vigneri, R1
Avola, R; Cohen, D; D'Agata, R; Pezzino, V; Polosa, P; Vigneri, R1
Goldfine, ID; Pezzino, V; Vigneri, R; Wong, KY1
Berstein, LM; Buslaeva, VP; Dilman, VM; Fedorov, SN; Kondratjev, VB; Nemirovsky, VS; Nikiforov, YF; Ostroumova, MN; Poroshina, TE; Seleznev, IK; Semiglazov, VF; Tsyrlina, EV; Vasilyeva, IA1
Bershteĭn, LM; Dil'man, VM; Ostroumova, MN; Vasil'eva, IA1
Bershteĭn, LM; Buslaeva, VP; Kondrat'ev, VB; Ostroumova, MN; Semiglazov, VF1
Dilman, VM; Ostroumova, MN; Tsyrlina, EV1
Bershteĭn, LM; Bobrov, IuF; Dil'man, VM; Kovaleva, IG; Tsyrlina, EV1
Dil'man, VM; Kirsanov, AI; Kovaleva, IG; Riabov, SI; Tsyrlina, EV1

Other Studies

14 other study(ies) available for phenformin and Breast Neoplasms

ArticleYear
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.
    Nature communications, 2021, 06-03, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Electron Transport Complex I; Energy Metabolism; Female; Glutathione; Humans; Interferon-gamma; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, SCID; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Oxidative Stress; Phenformin; Poly I-C; Reactive Oxygen Species; STAT1 Transcription Factor; Xenograft Model Antitumor Assays

2021
Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study.
    Acta pharmaceutica (Zagreb, Croatia), 2018, Dec-01, Volume: 68, Issue:4

    Topics: Administration, Oral; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Glucose; Humans; Hypoglycemic Agents; Metformin; Phenformin

2018
The biguanides metformin and phenformin inhibit angiogenesis, local and metastatic growth of breast cancer by targeting both neoplastic and microenvironment cells.
    International journal of cancer, 2015, Mar-15, Volume: 136, Issue:6

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Electron Transport Complex I; Female; Humans; Metformin; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Phenformin; Phosphorylation; TOR Serine-Threonine Kinases; Tumor Microenvironment

2015
Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Epithelial-Mesenchymal Transition; Female; Humans; Hypoglycemic Agents; MAP Kinase Signaling System; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Phenformin; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Phenformin as prophylaxis and therapy in breast cancer xenografts.
    British journal of cancer, 2012, Mar-13, Volume: 106, Issue:6

    Topics: Adenylate Kinase; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Histones; Humans; Ki-67 Antigen; Liver; Metformin; Mice; Mice, Nude; Phenformin; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Spleen; Tumor Burden; Xenograft Model Antitumor Assays

2012
Effect of metformin on insulin binding to receptors in cultured human lymphocytes and cancer cells.
    Diabetologia, 1982, Volume: 23, Issue:2

    Topics: Breast Neoplasms; Cells, Cultured; Cycloheximide; Humans; Insulin; Lymphocytes; Metformin; Phenformin; Receptor, Insulin

1982
Phenformin increases insulin binding to human cultured breast cancer cells.
    Diabetes, 1980, Volume: 29, Issue:4

    Topics: Breast Neoplasms; Cell Line; Female; Humans; Insulin; Kinetics; Phenformin; Receptor, Insulin

1980
Comparison of the in vitro effect of biguanides and sulfonylureas on insulin binding of its receptors in target cells.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:1

    Topics: Animals; Biguanides; Breast Neoplasms; Cell Line; Female; Fibroblasts; Humans; Insulin; Liver Neoplasms, Experimental; Lymphocytes; Metformin; Phenformin; Rats; Receptor, Insulin; Sulfonylurea Compounds

1982
Metabolic immunodepression and metabolic immunotherapy: an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances.
    Oncology, 1982, Volume: 39, Issue:1

    Topics: Age Factors; Body Weight; Breast Neoplasms; Clofibrate; Female; Hormones; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Leukocyte Count; Lipids; Lymphocyte Activation; Mastectomy; Middle Aged; Phenformin; Time Factors

1982
[Effect of phenformin and miscleron on the blood somatomedin activity level in breast cancer].
    Voprosy onkologii, 1980, Volume: 26, Issue:9

    Topics: Adult; Aged; Breast Neoplasms; Clofibrate; Female; Humans; Hyperlipidemias; Middle Aged; Phenformin; Somatomedins; Uterine Neoplasms

1980
[Effect of fenformin and miscleron on the delayed hypersensitivity reaction in breast cancer patients].
    Voprosy onkologii, 1980, Volume: 26, Issue:12

    Topics: Breast Neoplasms; Clofibrate; Dinitrochlorobenzene; Drug Therapy, Combination; Female; Humans; Hypersensitivity, Delayed; Hypolipidemic Agents; Middle Aged; Phenformin; Skin Tests; Time Factors

1980
Hypothalamic mechanisms of ageing and of specific age pathology--II. on the sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in adaptive homestasis.
    Experimental gerontology, 1979, Volume: 14, Issue:4

    Topics: Adaptation, Physiological; Adult; Aged; Aging; Animals; Breast Neoplasms; Corticosterone; Dexamethasone; Female; Homeostasis; Humans; Hydroxysteroids; Hypothalamo-Hypophyseal System; Male; Middle Aged; Phenformin; Rats

1979
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
    Voprosy onkologii, 1975, Volume: 21, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; Cholesterol; Clofibrate; Colonic Neoplasms; Endocrine System Diseases; Fatty Acids; Female; Growth Hormone; Humans; Insulin; Lipoproteins; Lung Neoplasms; Middle Aged; Neoplasms; Phenformin; Phenytoin; Phospholipids; Triglycerides; Uric Acid; Uterine Neoplasms

1975
[A decrease in body weight, cholesterol and blood sugar under the influence of phenformin (phenylbiguanide) in patients with cancer and atherosclerosis].
    Voprosy onkologii, 1972, Volume: 18, Issue:2

    Topics: Adult; Antineoplastic Agents; Arteriosclerosis; Blood Glucose; Body Weight; Breast Neoplasms; Cholesterol; Female; Humans; Male; Middle Aged; Phenformin; Uterine Neoplasms

1972