Page last updated: 2024-08-18

phenformin and Acidosis, Lactic

phenformin has been researched along with Acidosis, Lactic in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (20.51)	18.7374
1990's	18 (46.15)	18.2507
2000's	10 (25.64)	29.6817
2010's	2 (5.13)	24.3611
2020's	1 (2.56)	2.80

Authors

Authors	Studies
Fraser-Spears, R; Kim, SS; La-Viola, B; Ramsinghani, S; Sikazwe, D; Witte, AP; Yendapally, R	1
Billis, PA; Dykens, JA; Jamieson, J; Marroquin, L; Nadanaciva, S; Will, Y	1
Foti, G; Gattinoni, L; Mistraletti, G; Protti, A; Rossi, A; Rudiger, A; Russo, R; Singer, M; Tagliabue, P; Vecchio, S	1
Bando, K; Deguchi, J; Funabashi, H; Kimura, J; Kunimatsu, T; Ochiai, S; Seki, T	1
Kuroda, A; Yamasaki, Y	1
Kalakunja, A; Kumar, A; Nugent, K; Pirtle, F	1
BERNIER, GM; MILLER, M; SPRINGATE, CS	1
BERNSTEIN, S; MARTIN, HE; TRANQUADA, RE	1
MENGIS, CL	1
PHILLIPSON, EA; SPROULE, BJ	1
ARMANINO, LP; YOUNG, JM	1
Greyber, E; Pasternak, GA; Salpeter, EE; Salpeter, SR	1
Fimognari, FL; Incalzi, RA; Pastorelli, R	1
Ogihara, T; Tanaka, Y	1
Chan, AY; Ching, CK; Lai, CK; Mak, TW; Poon, WT; Wong, EN; Yan, WW	1
Antonelli Incalzi, R; Corsonello, A; Fimognari, FL; Pastorelli, R	1
Talwalkar, PG	1
McGuinness, ME; Talbert, RL	1
Lorber, DL; Lu, HC; Parikh, PP	1
Natalini, L; Quadrani, G; Ricci, F; Tessero, D; Vecchiarelli, P	1
Cheah, JS; Lee, KO; Yeoh, KG	1
Friedberg, JW; Rosand, J; Yang, JM	1
Meisheri, YV	1
Rojas Hidalgo, E	1
Enia, G; Garozzo, M; Zoccali, C	1
Capra, L; Cavalli, PL; Curto, V; Goia, F; Lanza, G; Mariano, F; Vincenti, R	1
Benzi, L; Capra, L; Cavalli, PL; Cecchetti, P; Curto, V; Goia, F; Lanza, G; Mariano, F; Merante, D; Rosatello, A	1
Butler-Jones, D; Stang, M; Wysowski, DK	1
Lalau, JD; Race, JM	2
Balasubramaniam, J	1
Maier, C; Wulf, H	1
Bianco, A; Ghirlanda, G; Greco, AV	1
Aguilar, C; García, JE; Reza, A; Rull, JA	1
Allison, NL; Bland, PS; Ilson, BE; Jorkasky, DK; Stote, RM	1
Chandalia, HB; Rangnath, M	1
Conget, JI; Esmatjes, E; Goday, A; Vendrell, J	1
Aluffi, E; Bruno, A; Carta, Q; Cavallo-Perin, P; Estivi, P; Lenti, G; Pagano, G	1
Strandberg, K; Wiholm, BE	1

Reviews

7 review(s) available for phenformin and Acidosis, Lactic

Article	Year
A review of phenformin, metformin, and imeglimin. Drug development research, 2020, Volume: 81, Issue:4 Topics: Acidosis, Lactic; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Phenformin; Triazines	2020
[Adverse effect of biguanides]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9 Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus, Type 2; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Phenformin; Vitamin B 12 Deficiency	2002
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: systematic review and meta-analysis. Archives of internal medicine, 2003, Nov-24, Volume: 163, Issue:21 Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Phenformin; Risk Assessment	2003
[Diabetic lactic acidosis]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Sep-28, Volume: Suppl 3 Topics: Acidosis, Lactic; Contraindications; Diabetic Ketoacidosis; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Phenformin; Sodium Bicarbonate	2006
Phenformin-induced lactic acidosis: a forgotten adverse drug reaction. The Annals of pharmacotherapy, 1993, Volume: 27, Issue:10 Topics: Acidosis, Lactic; Diabetes Mellitus; Dichloroacetic Acid; Drug and Narcotic Control; Humans; Insulin; Male; Middle Aged; Phenformin; Renal Dialysis; Sodium Bicarbonate; Sodium Chloride	1993
[Antidiabetic biguanides and lactic acidosis]. Revista clinica espanola, 1997, Volume: 197, Issue:8 Topics: Acidosis, Lactic; Biguanides; Buformin; Diabetes Mellitus; Humans; Hypoglycemic Agents; Models, Biological; Phenformin; Sulfonylurea Compounds	1997
Metformin and lactic acidosis in diabetic humans. Diabetes, obesity & metabolism, 2000, Volume: 2, Issue:3 Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Humans; Hypoglycemic Agents; Metformin; Phenformin; Prognosis	2000

Trials

1 trial(s) available for phenformin and Acidosis, Lactic

Article	Year
The hyperlactatemic effect of biguanides: a comparison between phenformin and metformin during a 6-month treatment. Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques, 1989, Volume: 11, Issue:1 Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Female; Humans; Male; Metformin; Middle Aged; Phenformin; Time Factors	1989

Article

Year

The hyperlactatemic effect of biguanides: a comparison between phenformin and metformin during a 6-month treatment.

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques, 1989, Volume: 11, Issue:1

Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Female; Humans; Male; Metformin; Middle Aged; Phenformin; Time Factors

1989

Other Studies

31 other study(ies) available for phenformin and Acidosis, Lactic

Article	Year
Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro. Toxicology and applied pharmacology, 2008, Dec-01, Volume: 233, Issue:2 Topics: Acidosis, Lactic; Animals; Blood Glucose; Buformin; Cell Line; Cell Respiration; Cell Survival; Culture Media; Glutathione; Glycolysis; Hepatocytes; Humans; Hypoglycemic Agents; Lactic Acid; Male; Membrane Potential, Mitochondrial; Metformin; Mitochondria, Liver; Oxidation-Reduction; Phenformin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2008
Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication. Critical care (London, England), 2010, Volume: 14, Issue:1 Topics: Acidosis, Lactic; Aged; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Oxygen Consumption; Phenformin; Retrospective Studies	2010
Comparison of potential risks of lactic acidosis induction by biguanides in rats. Regulatory toxicology and pharmacology : RTP, 2010, Volume: 58, Issue:1 Topics: Acidosis, Lactic; Animals; Dose-Response Relationship, Drug; Female; Hypoglycemic Agents; Lactic Acid; Male; Metformin; Phenformin; Rats; Rats, Inbred F344	2010
Severe acidosis in a patient with type 2 diabetes mellitus, hypertension, and renal failure. Chest, 2003, Volume: 123, Issue:5 Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Humans; Hypertension; Hypoglycemic Agents; Kidney Failure, Chronic; Male; Middle Aged; Phenformin	2003
Lactic acidosis and phenformin hydrochloride. JAMA, 1963, Apr-06, Volume: 184 Topics: Acidosis; Acidosis, Lactic; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Lactates; Phenformin	1963
Irreversible lactic acidosis associated with phenformine therapy. Report of three cases. JAMA, 1963, Apr-06, Volume: 184 Topics: Acidosis; Acidosis, Lactic; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Lactates; Phenformin	1963
LACTIC ACID ACIDEMIA AND PHENFORMIN. Rocky Mountain medical journal, 1964, Volume: 61 Topics: Acidosis; Acidosis, Lactic; Blood; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Lactates; Lactic Acid; Phenformin; Toxicology	1964
THE CLINICAL SIGNIFICANCE OF ELEVATED BLOOD LACTATE. Canadian Medical Association journal, 1965, Jun-26, Volume: 92 Topics: Acidosis; Acidosis, Lactic; Blood; Chemical Phenomena; Chemistry; Geriatrics; Humans; Hypertension; Hypertension, Pulmonary; Hypoxia; Lactates; Lactic Acid; Phenformin; Prognosis; Shock	1965
LACTIC ACIDOSIS AND PHENFORMIN INTOXICATION. REPORT OF TWO CASES WITH REVIEW OF LITERATURE. California medicine, 1965, Volume: 103 Topics: Acidosis; Acidosis, Lactic; Geriatrics; Humans; Phenformin; Therapeutics; Toxicology	1965
Phenformin-induced lactic acidosis in an older diabetic patient: a recurrent drama (phenformin and lactic acidosis). Diabetes care, 2006, Volume: 29, Issue:4 Topics: Acidosis, Lactic; Aged; Drug and Narcotic Control; Drugs, Chinese Herbal; Humans; Hypoglycemic Agents; Male; Phenformin	2006
Hazards posed by a banned drug--phenformin is still hanging around. Hong Kong medical journal = Xianggang yi xue za zhi, 2008, Volume: 14, Issue:1 Topics: Acidosis, Lactic; Aged; Diabetes Mellitus; Drug Contamination; Drug Synergism; Drugs, Chinese Herbal; Female; Hong Kong; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenformin; Urine	2008
Older age and phenformin therapy: a dangerous association. Internal and emergency medicine, 2008, Volume: 3, Issue:4 Topics: Acidosis, Lactic; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Confidence Intervals; Contraindications; Diabetes Mellitus; Female; Hospitalization; Humans; Hypoglycemic Agents; Italy; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phenformin; Risk Factors	2008
Phenformin induced lactic acidosis in an elderly NIDDM patient. The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:8 Topics: Acidosis, Lactic; Aged; Diabetes Mellitus, Type 2; Humans; Male; Phenformin	1994
Phenformin-associated lactic acidosis due to imported phenformin. Diabetes care, 1996, Volume: 19, Issue:12 Topics: Acidosis, Lactic; Aged; Blood Glucose; China; Diabetes Mellitus, Type 2; Fluid Therapy; Humans; Hypoglycemic Agents; Male; Panax; Phenformin; Plants, Medicinal; Respiration, Artificial; United States	1996
[Lactic acidosis induced by phenformin: a still forgotten iatrogenic complication]. Minerva anestesiologica, 1995, Volume: 61, Issue:10 Topics: Acidosis, Lactic; Aged; Female; Humans; Hypoglycemic Agents; Male; Phenformin	1995
Fatal lactic acidosis from imported phenformin--report of two cases. Singapore medical journal, 1996, Volume: 37, Issue:5 Topics: Acidosis, Lactic; Aged; China; Diabetes Mellitus, Type 2; Fatal Outcome; Humans; Hypoglycemic Agents; Male; Phenformin; Singapore	1996
Fatal phenformin-associated lactic acidosis. Annals of internal medicine, 1997, Jul-15, Volume: 127, Issue:2 Topics: Acidosis, Lactic; Fatal Outcome; Female; Haiti; Humans; Hypoglycemic Agents; Middle Aged; Phenformin	1997
Phenformin induced lactic acidosis. The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:2 Topics: Acidosis, Lactic; Aged; Causality; Humans; Hypoglycemic Agents; Lung Diseases, Obstructive; Phenformin	1995
Lactic acidosis induced by phenformin is still a public health problem in Italy. BMJ (Clinical research ed.), 1997, Nov-29, Volume: 315, Issue:7120 Topics: Acidosis, Lactic; Humans; Hypoglycemic Agents; Italy; Phenformin	1997
[Insufficient correction of blood bicarbonate levels in biguanide lactic acidosis treated with CVVH and bicarbonate replacement fluids]. Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 1997, Volume: 49, Issue:3 Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Bicarbonates; Buffers; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatal Outcome; Female; Fluid Therapy; Hemofiltration; Humans; Hypoglycemic Agents; Phenformin	1997
Efficacy of continuous venovenous haemofiltration (CVVH) in the treatment of severe phenformin-induced lactic acidosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:4 Topics: Acidosis, Lactic; Aged; Female; Hemofiltration; Humans; Hypoglycemic Agents; Phenformin	1998
Incidence of lactic acidosis in metformin users. Diabetes care, 1999, Volume: 22, Issue:6 Topics: Acidosis, Lactic; Cohort Studies; Databases as Topic; Death Certificates; Humans; Hypoglycemic Agents; Incidence; Lactates; Metformin; Phenformin; Registries; Saskatchewan; United States; United States Food and Drug Administration	1999
Lactic acidosis in metformin therapy. Drugs, 1999, Volume: 58 Suppl 1 Topics: Acidosis, Lactic; Adult; Aged; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Lactic Acid; Metformin; Middle Aged; Phenformin; Retrospective Studies; Risk Factors	1999
Phenformin induced lactic acidosis in an elderly NIDDM patient. The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:3 Topics: Acidosis, Lactic; Aged; Asthma; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Male; Phenformin	1995
[Recommendations for perioperative interruption of metformin medication]. Deutsche medizinische Wochenschrift (1946), 2001, Oct-26, Volume: 126, Issue:43 Topics: Acidosis, Lactic; Contraindications; Humans; Hypoglycemic Agents; Metformin; Perioperative Care; Phenformin; Risk Factors	2001
[Lactic acidosis, hyperamylasemia, and phenformin]. Minerva medica, 1992, Volume: 83, Issue:12 Topics: Acidosis, Lactic; Aged; Amylases; Diabetes Mellitus, Type 2; Female; Humans; Middle Aged; Phenformin	1992
Biguanide related lactic acidosis: incidence and risk factors. Archives of medical research, 1992,Spring, Volume: 23, Issue:1 Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Contraindications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Emergencies; Female; Humans; Incidence; Male; Metformin; Mexico; Middle Aged; Odds Ratio; Phenformin; Prospective Studies; Retrospective Studies; Risk Factors; Sulfonylurea Compounds	1992
Metabolic acidosis in a diabetic man. Hospital practice (Office ed.), 1990, Oct-15, Volume: 25, Issue:10 Topics: Acidosis, Lactic; Chronic Disease; Combined Modality Therapy; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypertension; Male; Middle Aged; Phenformin	1990
Biguanide-induced lactic acidosis. The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:9 Topics: Acidosis, Lactic; Adult; Diabetes Mellitus, Type 2; Follow-Up Studies; Humans; Lactates; Lactic Acid; Male; Phenformin; Prospective Studies	1990
[Lactic acidosis caused by phenformin: the most recent]. Anales de medicina interna (Madrid, Spain : 1984), 1989, Volume: 6, Issue:6 Topics: Acidosis, Lactic; Aged; Diabetes Mellitus, Type 2; Female; Humans; Phenformin	1989
Regulatory decisions. Emphasis on safety issues. Medical toxicology, 1986, Volume: 1 Suppl 1 Topics: Acidosis, Lactic; Anti-Inflammatory Agents, Non-Steroidal; Drug-Related Side Effects and Adverse Reactions; Glyburide; Humans; Legislation, Drug; Phenformin; Registries; Sweden; Zimeldine	1986