phenethylamine has been researched along with Idiopathic Parkinson Disease in 11 studies
phenethylamine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7016
2-phenylethylamine : A phenylethylamine having the phenyl substituent at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deprenyl/Selegiline (DEP), created by Joseph Knoll in the 1960s, registered in more than 60 countries to treat Parkinson's disease, Alzheimer's disease, major depressive disorder; and used as an anti-aging drug, achieved its place in research and therapy as the first selective inhibitor of B-type monoamine oxidase (MAO-B)." | 4.93 | The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015). ( Miklya, I, 2016) |
| " It has been reported recently that long-term administration of β-PEA in rodents causes neurochemical and behavioral alterations similar to that produced by parkinsonian neurotoxins." | 2.49 | Contribution of β-phenethylamine, a component of chocolate and wine, to dopaminergic neurodegeneration: implications for the pathogenesis of Parkinson's disease. ( Bhattacharjee, N; Borah, A; Mazumder, MK; Paul, R, 2013) |
| "Concentrations of PEA in CSF in Parkinson's disease were significantly lower (mean 205 (SD 131) pg/ml) than in patients with peripheral neuropathy (433 (SD 254) pg/ml) and controls (387 (SD 194) pg/ml)." | 1.30 | Decreased beta-phenylethylamine in CSF in Parkinson's disease. ( Matsuishi, T; Shoji, H; Yamada, S; Zhou, G, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borah, A | 1 |
| Paul, R | 1 |
| Mazumder, MK | 1 |
| Bhattacharjee, N | 1 |
| Miklya, I | 1 |
| Gluck, MR | 1 |
| Zeevalk, GD | 1 |
| Yu, PH | 1 |
| Jarman, J | 1 |
| Glover, V | 1 |
| Sandler, M | 1 |
| Turjanski, N | 1 |
| Stern, G | 1 |
| La Croix, R | 1 |
| Dostert, P | 1 |
| Strolin Benedetti, M | 1 |
| Gargalidis-Moudanos, C | 1 |
| Pizzinat, N | 1 |
| Javoy-Agid, F | 1 |
| Remaury, A | 1 |
| Parini, A | 1 |
| Yamakawa, T | 1 |
| Ohta, S | 1 |
| Zhou, G | 2 |
| Shoji, H | 2 |
| Yamada, S | 2 |
| Matsuishi, T | 2 |
| Miura, Y | 2 |
3 reviews available for phenethylamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Contribution of β-phenethylamine, a component of chocolate and wine, to dopaminergic neurodegeneration: implications for the pathogenesis of Parkinson's disease.
Topics: Animals; Cacao; Dopaminergic Neurons; Humans; Nerve Degeneration; Oxidative Stress; Parkinson Diseas | 2013 |
The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015).
Topics: Aging; Alzheimer Disease; Animals; Brain; Catecholamines; Depressive Disorder, Major; Dopamine; Hist | 2016 |
Pharmacological and clinical implications of MAO-B inhibitors.
Topics: Aging; Alzheimer Disease; Animals; Depressive Disorder; Humans; Mental Disorders; Monoamine Oxidase | 1994 |
8 other studies available for phenethylamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Inhibition of brain mitochondrial respiration by dopamine and its metabolites: implications for Parkinson's disease and catecholamine-associated diseases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Cell Respiration; Dopamine | 2004 |
Platelet monoamine oxidase B activity in Parkinson's disease: a re-evaluation.
Topics: Aged; Blood Platelets; Dopamine; Female; Humans; Male; Middle Aged; Monoamine Oxidase; Parkinson Dis | 1993 |
Sensitive high-performance liquid chromatographic method for the determination of 2-phenylethylamine in human urine.
Topics: Aged; Antiparkinson Agents; Chromatography, High Pressure Liquid; Circadian Rhythm; Female; Humans; | 1996 |
I2-imidazoline binding sites and monoamine oxidase activity in human postmortem brain from patients with Parkinson's disease.
Topics: Aged; Aged, 80 and over; Brain; Cerebral Cortex; Female; Humans; Idazoxan; Imidazoline Receptors; Ma | 1997 |
Isolation of 1-methyl-1,2,3,4-tetrahydroisoquinoline-synthesizing enzyme from rat brain: a possible Parkinson's disease-preventing enzyme.
Topics: Animals; Brain; Chromatography, Gel; Deoxycholic Acid; Hydrogen-Ion Concentration; Isoquinolines; Ma | 1997 |
Decreased beta-phenylethylamine in CSF in Parkinson's disease.
Topics: Aged; Chromatography, Gas; Female; Homovanillic Acid; Humans; Levodopa; Male; Mass Spectrometry; Mid | 1997 |
Platelet monoamine oxidase B and plasma beta-phenylethylamine in Parkinson's disease.
Topics: Aged; Analysis of Variance; Blood Platelets; Female; Humans; Male; Middle Aged; Monoamine Oxidase; P | 2001 |
Plasma beta-phenylethylamine in Parkinson's disease.
Topics: Aged; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Parkinson Disease; Ph | 2000 |