phenethylamine has been researched along with Alzheimer Disease in 4 studies
phenethylamine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7016
2-phenylethylamine : A phenylethylamine having the phenyl substituent at the 2-position.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deprenyl/Selegiline (DEP), created by Joseph Knoll in the 1960s, registered in more than 60 countries to treat Parkinson's disease, Alzheimer's disease, major depressive disorder; and used as an anti-aging drug, achieved its place in research and therapy as the first selective inhibitor of B-type monoamine oxidase (MAO-B)." | 4.93 | The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015). ( Miklya, I, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miklya, I | 1 |
| Sterling, J | 1 |
| Herzig, Y | 1 |
| Goren, T | 1 |
| Finkelstein, N | 1 |
| Lerner, D | 1 |
| Goldenberg, W | 1 |
| Miskolczi, I | 1 |
| Molnar, S | 1 |
| Rantal, F | 1 |
| Tamas, T | 1 |
| Toth, G | 1 |
| Zagyva, A | 1 |
| Zekany, A | 1 |
| Finberg, J | 1 |
| Lavian, G | 1 |
| Gross, A | 1 |
| Friedman, R | 1 |
| Razin, M | 1 |
| Huang, W | 1 |
| Krais, B | 1 |
| Chorev, M | 1 |
| Youdim, MB | 1 |
| Weinstock, M | 1 |
| Smith, RC | 1 |
| Ho, BT | 1 |
| Kralik, P | 1 |
| Vroulis, G | 1 |
| Gordon, J | 1 |
| Wolff, J | 1 |
| Yu, PH | 1 |
2 reviews available for phenethylamine and Alzheimer Disease
| Article | Year |
|---|---|
The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015).
Topics: Aging; Alzheimer Disease; Animals; Brain; Catecholamines; Depressive Disorder, Major; Dopamine; Hist | 2016 |
Pharmacological and clinical implications of MAO-B inhibitors.
Topics: Aging; Alzheimer Disease; Animals; Depressive Disorder; Humans; Mental Disorders; Monoamine Oxidase | 1994 |
2 other studies available for phenethylamine and Alzheimer Disease
| Article | Year |
|---|---|
Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Carbamates; | 2002 |
Platelet monamine oxidase in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Blood Platelets; Dementia; Humans; Monoamine Oxidase; Phenethylamines; Subs | 1982 |