phenethyl isothiocyanate has been researched along with Neoplasms in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, Y; Huang, P; Li, X; Lu, W; Luo, B; Wang, J; Wen, S; Yang, J | 1 |
| Fahey, JW; Kensler, TW; Palliyaguru, DL; Yuan, JM | 1 |
| Chen, J; Hu, H; Huang, X; Li, F; Li, Y; Li, Z; Tang, Y; Wu, H; Wu, Y; Xiao, C; Yang, H; Yang, X; Yi, Y; Zhang, B | 1 |
| Gerhauser, C | 1 |
| Hu, W; Hu, X; Wu, H; Zhu, C | 1 |
| Ioannides, C; Konsue, N | 1 |
| Eisa, NH; Eissa, LA; El-Shishtawy, MM; ElSherbiny, NM; Shebl, AM | 1 |
| Aggarwal, M; Agostino, SD; Avantaggiati, ML; Berry, D; Blandino, G; Chung, FL; Cruz, I; Dyba, M; Fu, Y; Jacobs, A; Kallakury, B; Mueller, SC; Saxena, R; Sinclair, E; Wang, X | 1 |
| Gill, C; Glei, M; Hofmann, T; Kuhnert, A; Pool-Zobel, BL; Rowland, IR; Schubert, A | 1 |
| Cheung, KL; Kong, AN | 1 |
| Bagchi, S; Elangovan, I; Kopanja, D; Raychaudhuri, P; Roy, N | 1 |
| Chiao, JW; Chung, FL; Conaway, CC; Liu, D; Ramaswamy, G; Wang, L; Wu, H | 1 |
| Choi, S; Lew, KL; Nelson, JB; Singh, SV; Xiao, D; Zeng, Y | 1 |
| Achanta, G; Arlinghaus, RB; Chen, Z; Chiao, PJ; Demizu, Y; Huang, P; Liu, J; Pelicano, H; Trachootham, D; Zhang, H; Zhou, Y | 1 |
| Hua, X; Wu, XJ | 1 |
| Thornalley, PJ; Xu, K | 1 |
5 review(s) available for phenethyl isothiocyanate and Neoplasms
| Article | Year |
|---|---|
Isothiocyanates: Translating the Power of Plants to People.
Topics: Brassica; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Isothiocyanates; Neoplasms; Skin Diseases; Sulfoxides; Treatment Outcome; Vegetables | 2018 |
Epigenetic impact of dietary isothiocyanates in cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Brassica; Catechin; Chemoprevention; Diet; DNA Methylation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; MicroRNAs; Neoplasms; NF-E2-Related Factor 2; Signal Transduction; Sulfoxides | 2013 |
A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism.
Topics: Activation, Metabolic; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Damage; Humans; Isothiocyanates; Metabolic Detoxication, Phase II; Neoplasms; Protective Factors; Risk Factors | 2015 |
Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cytochrome P-450 Enzyme Inhibitors; Diet; Enzyme Induction; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; MAP Kinase Signaling System; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Sulfoxides; Thiocyanates | 2010 |
Targeting ROS: selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Brassicaceae; Cell Transformation, Neoplastic; Fusion Proteins, bcr-abl; Humans; Isothiocyanates; Neoplasms; Oncogene Protein p21(ras); Reactive Oxygen Species | 2007 |
2 trial(s) available for phenethyl isothiocyanate and Neoplasms
| Article | Year |
|---|---|
No evident dose-response relationship between cellular ROS level and its cytotoxicity--a paradoxical issue in ROS-based cancer therapy.
Topics: Acidosis, Lactic; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Proliferation; Dioxolanes; Dose-Response Relationship, Drug; Glutathione; Humans; Isothiocyanates; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured | 2014 |
Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cells.
Topics: Anticarcinogenic Agents; Cells, Cultured; Cross-Over Studies; Dose-Response Relationship, Drug; Gene Expression; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Glutathione Transferase; Humans; Isothiocyanates; Leukocytes, Mononuclear; Nasturtium; Neoplasms; Plant Extracts; Polymorphism, Genetic; Superoxide Dismutase | 2009 |
9 other study(ies) available for phenethyl isothiocyanate and Neoplasms
| Article | Year |
|---|---|
Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Glutathione; Isothiocyanates; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasms; Neoplastic Stem Cells; Oxidation-Reduction; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2017 |
Potentiating photodynamic therapy of ICG-loaded nanoparticles by depleting GSH with PEITC.
Topics: Animals; Cell Survival; Drug Synergism; Glutathione; Hep G2 Cells; Humans; Hydroxyethyl Starch Derivatives; Hyperthermia, Induced; Indocyanine Green; Isothiocyanates; Lasers; Mice; Microscopy, Confocal; Nanoparticles; Neoplasms; Oleic Acid; Photochemotherapy; Reactive Oxygen Species; Singlet Oxygen; Tissue Distribution | 2019 |
Phenethyl isothiocyanate potentiates anti-tumour effect of doxorubicin through Akt-dependent pathway.
Topics: Animals; Anticarcinogenic Agents; Caspase 3; Caspase 9; Cell Death; Cell Movement; Cell Proliferation; Cell Survival; DNA; Doxorubicin; Drug Synergism; Female; Hep G2 Cells; Humans; Isothiocyanates; MCF-7 Cells; Mice; Neoplasms; Oxidative Stress; Protein Binding; Proto-Oncogene Proteins c-akt; Signal Transduction; Survival Analysis; Transcription Factor RelA | 2015 |
Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 2; Diet; Histones; Humans; Isothiocyanates; Mutant Proteins; Mutation; Neoplasms; Oxidation-Reduction; Proteasome Endopeptidase Complex; Protein Conformation; Proteolysis; Transcriptional Activation; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays; Zinc | 2016 |
Tumor regression by phenethyl isothiocyanate involves DDB2.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Male; Mice; Neoplasms; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2013 |
Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Separation; Coloring Agents; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Flow Cytometry; G1 Phase; Humans; Isothiocyanates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitosis; Neoplasm Transplantation; Neoplasms; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; S Phase; Time Factors; Tumor Suppressor Proteins; Up-Regulation; Vegetables | 2004 |
Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
Topics: Adenocarcinoma; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Immunoblotting; Intracellular Membranes; Isothiocyanates; Male; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Neoplasms; Plant Preparations; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Vegetables | 2005 |
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.
Topics: Animals; Antioxidants; Cell Death; Cell Line; Cell Transformation, Neoplastic; Fusion Proteins, bcr-abl; Glutathione; Humans; Isothiocyanates; Mice; Neoplasms; Oncogene Protein p21(ras); Reactive Oxygen Species; Survival Rate; Xenograft Model Antitumor Assays | 2006 |
Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK.
Topics: Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Neoplasms; Phosphorylation; Phosphotyrosine; Signal Transduction | 2001 |