Page last updated: 2024-08-22

phenethyl isothiocyanate and Leukemia

phenethyl isothiocyanate has been researched along with Leukemia in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cavell, BE; Coldwell, MJ; Forconi, F; Hidalgo, MS; Krysov, S; Lemm, E; Leonard, E; Packham, G; Steele, AJ; Stevenson, FK; Valle-Argos, B; Willis, AE; Wilmore, S; Yeomans, A1
Bhalla, K; Chen, G; Fiskus, W; Garcia-Manero, G; Hu, Y; Huang, P; Jia, Y; Keating, M; Lu, W; Wei, Y; Yang, H; Zhang, H; Zhang, W1
Budhraja, A; Chen, D; Chen, J; Cheng, S; Gao, N; Liu, EH; Shi, X; Yang, Z; Zhang, Z1
Balayssac, S; Ballot, C; Briand, G; Dammak, A; Dauphin, V; Formstecher, P; Idziorek, T; Jendoubi, M; Joha, S; Jonneaux, A; Kluza, J; Maboudou, P; Malet-Martino, M; Marchetti, P; Quesnel, B1
Chen, G; Chen, Z; Hu, Y; Huang, P1
Thornalley, PJ; Xu, K1

Other Studies

6 other study(ies) available for phenethyl isothiocyanate and Leukemia

ArticleYear
PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells.
    Oncotarget, 2016, 11-15, Volume: 7, Issue:46

    Topics: Antibodies, Anti-Idiotypic; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Isothiocyanates; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Phosphorylation; Protein Biosynthesis; Receptors, Antigen, B-Cell; RNA, Messenger; Stress, Physiological; Transcription, Genetic

2016
Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate.
    Blood, 2010, Oct-14, Volume: 116, Issue:15

    Topics: Antioxidants; Base Sequence; Cell Line, Tumor; Cell Survival; DNA Primers; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; Isothiocyanates; Leukemia; Leukemia, Myeloid; NADPH Oxidases; NF-E2-Related Factor 2; Oxidation-Reduction; Reactive Oxygen Species; Tumor Cells, Cultured; U937 Cells; Vorinostat

2010
Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways.
    Cell death & disease, 2011, Apr-07, Volume: 2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Female; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; Male; Mice; Mice, SCID; Proto-Oncogene Proteins c-akt; Signal Transduction; U937 Cells; Xenograft Model Antitumor Assays

2011
Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Arsenic Trioxide; Arsenicals; Benzamides; Cell Death; Cell Line, Tumor; Cell Respiration; Drug Resistance, Neoplasm; Electron Transport; Energy Metabolism; Glucose; Imatinib Mesylate; Isothiocyanates; Leukemia; Mice; Mitochondria; Models, Biological; Oxidative Stress; Oxides; Piperazines; Pyrimidines; Reactive Oxygen Species

2011
Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by β-phenethyl isothiocyanate: mechanisms for anti-leukemia activity.
    Antioxidants & redox signaling, 2011, Dec-15, Volume: 15, Issue:12

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Respiration; Cell Survival; Electron Transport Complex I; Glutathione; HL-60 Cells; Humans; Isothiocyanates; Leukemia; Membrane Potentials; Mitochondria; Models, Biological; NADH Dehydrogenase; Nitric Oxide; Reactive Oxygen Species

2011
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro.
    Biochemical pharmacology, 2000, Jul-15, Volume: 60, Issue:2

    Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Chemoprevention; Cysteine; Diet; DNA, Neoplasm; Food Preservatives; HL-60 Cells; Humans; Hydrolysis; Isothiocyanates; Leukemia; Lymphocytes; RNA, Neoplasm; Tumor Cells, Cultured

2000