Page last updated: 2024-08-22

phenethyl isothiocyanate and Breast Cancer

phenethyl isothiocyanate has been researched along with Breast Cancer in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's13 (76.47)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Hao, M; Zhang, T; Zhang, W1
Mukherjee, S; Roy, M; Sarkars, R1
Hahm, ER; Sakao, K; Singh, SV1
Dave, RA; Morris, ME1
Biswas, J; Mukherjee, S; Roy, M; Sarkar, R1
Bui, LC; Cariou, K; Dodd, RH; Dupret, JM; Duval, R; Mathieu, C; Petit, E; Rodrigues-Lima, F; Xu, X1
Ding, L; Kang, L; Wang, ZY1
Brazeau, DA; Morris, ME; Telang, U1
Cavell, BE; Packham, G; Syed Alwi, SS; Wang, XH1
Kang, L; Wang, ZY1
Cavell, BE; Morris, ME; Packham, G; Parry, BM; Syed Alwi, SS; Telang, U1
Chung, FL; Govind, S; Mi, L; Roy, R; Sajankila, SP; Wang, X1
Hahm, ER; Singh, SV1
Ávila, R; Castilla, C; Flores, ML; Japón, MA; Ruiz-Borrego, M; Sáez, C1
Cavell, BE; Donlevy, A; Packham, G; Syed Alwi, SS1
Gupta, P; Srivastava, SK1
Aras, U; Gandhi, YA; Masso-Welch, PA; Morris, ME1

Reviews

1 review(s) available for phenethyl isothiocyanate and Breast Cancer

ArticleYear
Pharmacokinetics and pharmacodynamics of phenethyl isothiocyanate: implications in breast cancer prevention.
    The AAPS journal, 2014, Volume: 16, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Female; Humans; Isothiocyanates; Rats

2014

Other Studies

16 other study(ies) available for phenethyl isothiocyanate and Breast Cancer

ArticleYear
Phenethyl isothiocyanate reduces breast cancer stem cell-like properties by epigenetic reactivation of CDH1.
    Oncology reports, 2021, Volume: 45, Issue:1

    Topics: Anticarcinogenic Agents; Antigens, CD; Breast Neoplasms; Cadherins; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Neoplastic Stem Cells; Tumor Stem Cell Assay; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2021
Targeting heat shock proteins by phenethyl isothiocyanate results in cell-cycle arrest and apoptosis of human breast cancer cells.
    Nutrition and cancer, 2013, Volume: 65, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; DNA Fragmentation; Heat-Shock Proteins; Humans; Isothiocyanates; MCF-7 Cells; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2013
In vitro and in vivo effects of phenethyl isothiocyanate treatment on vimentin protein expression in cancer cells.
    Nutrition and cancer, 2013, Volume: 65 Suppl 1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Gene Knockdown Techniques; Humans; Isothiocyanates; Male; Mice; Prostatic Neoplasms; RNA Interference; RNA, Small Interfering; Vimentin

2013
Phenethyl isothiocyanate, by virtue of its antioxidant activity, inhibits invasiveness and metastatic potential of breast cancer cells: HIF-1α as a putative target.
    Free radical research, 2016, Volume: 50, Issue:1

    Topics: Antioxidants; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isothiocyanates; Neoplasm Invasiveness; Neoplasm Metastasis

2016
Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens.
    Oncotarget, 2016, Feb-23, Volume: 7, Issue:8

    Topics: Acetylation; Amines; Arylamine N-Acetyltransferase; Breast Neoplasms; Carcinogens; DNA Adducts; Enzyme Inhibitors; Female; Humans; Isothiocyanates; Kinetics; Tumor Cells, Cultured

2016
Isothiocyanates repress estrogen receptor alpha expression in breast cancer cells.
    Oncology reports, 2009, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor alpha; Female; Humans; Isothiocyanates; Reverse Transcriptase Polymerase Chain Reaction; Transfection

2009
Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:3

    Topics: Breast Neoplasms; Cell Line; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mammary Glands, Human; Oligonucleotide Array Sequence Analysis; Sulfoxides; Thiocyanates

2009
Inhibition of hypoxia inducible factor by phenethyl isothiocyanate.
    Biochemical pharmacology, 2009, Aug-01, Volume: 78, Issue:3

    Topics: Blotting, Western; Breast Neoplasms; Cell Division; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isothiocyanates; Phosphorylation; Procollagen-Proline Dioxygenase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Von Hippel-Lindau Tumor Suppressor Protein

2009
Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-alpha36.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:6B

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Estradiol; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Female; Fulvestrant; Genome, Human; Humans; Isothiocyanates; Leupeptins; Phosphorylation; Signal Transduction

2010
In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study.
    The British journal of nutrition, 2010, Volume: 104, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Leukocytes, Mononuclear; Middle Aged; Nasturtium; Phosphoproteins; Phosphorylation; Phytotherapy; Pilot Projects; Plant Extracts; Plant Leaves; Transcription Factors

2010
Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Butadienes; Caspase 3; Cell Line, Tumor; Cisplatin; Drug Synergism; Female; HeLa Cells; Humans; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Uterine Cervical Neoplasms

2011
Bim contributes to phenethyl isothiocyanate-induced apoptosis in breast cancer cells.
    Molecular carcinogenesis, 2012, Volume: 51, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Breast Neoplasms; Cell Line, Tumor; Female; Gene Silencing; Humans; Isothiocyanates; Membrane Proteins; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2

2012
Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction.
    Breast cancer research and treatment, 2012, Volume: 133, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Isothiocyanates; M Phase Cell Cycle Checkpoints; Paclitaxel; Protein Binding

2012
Differential induction of apoptosis in human breast cancer cell lines by phenethyl isothiocyanate, a glutathione depleting agent.
    Cell stress & chaperones, 2012, Volume: 17, Issue:5

    Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Female; Glutathione; Humans; Isothiocyanates; MCF-7 Cells; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-bcl-2

2012
Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models.
    BMC medicine, 2012, Jul-24, Volume: 10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mice; Mice, Inbred NOD; Mice, SCID; Phosphorylation; Receptor, ErbB-2; RNA, Small Interfering; STAT3 Transcription Factor; Transgenes; Tumor Burden; Xenograft Model Antitumor Assays

2012
Chemopreventive and anti-angiogenic effects of dietary phenethyl isothiocyanate in an N-methyl nitrosourea-induced breast cancer animal model.
    Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:2

    Topics: Alkylating Agents; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Breast Neoplasms; Diet; Disease Models, Animal; Female; Isothiocyanates; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tumor Burden

2013