phenethicillin and Streptococcal-Infections

Group A beta-hemolytic streptococci (GAS) are known to be capable of evoking sterile arthritis. Reactive arthritis (ReA) has been reported sporadically following primary infection with group C and group G beta-hemolytic streptococci (GCS, GGS). We prospectively studied 4 cases of ReA secondary to throat infection with GCS and GGS.. Four patients with arthritis secondary to throat infection were seen. Three patients were Dutch, one was Indonesian; female/male ratio was 1/3; mean age was 30 years (range 18-46). Diagnostic evaluation included culture of throat swab and serological screening.. All patients presented with a nonmigratory asymmetrical arthritis: monoarthritis in one patient, oligoarthritis in 3. Culture of throat swab was positive in all. Antistreptolysin-O (ASO) titer rose significantly in 2 patients, and anti-DNase-B rose in 2 patients. ASO was maximal (mean 1000 U/ml; range 890-1110) and anti-DNase-B was 395 U/ml (range 290-500). Treatment consisted of feneticillin for 5 days; nonsteroidal antiinflammatory drugs were prescribed on demand. All patients recovered fully in 3 to 12 weeks.. These cases provide evidence of a benign non-group A streptococcal ReA, i.e., secondary to GCS or GGS. The presence of the organism in the throat along with the elevation of antibody to streptococcal products is important for the diagnosis of GCS/GGS associated ReA. A positive throat culture is needed for differentiation from GAS associated poststreptococcal ReA, because prophylactic measures are effective only in GAS associated sequelae, but not in GCS/GGS associated ReA.

Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antistreptolysin; Arthritis, Reactive; Deoxyribonucleoproteins; Female; Humans; Male; Middle Aged; Penicillins; Pharyngitis; Prohibitins; Streptococcal Infections; Streptococcus

We present the case of a 38-year-old man who developed acute myopericarditis, mimicking acute myocardial infarction, as manifested by electrocardiographic, echocardiographic alterations and elevated cardiac enzymes complicating Lancefield group A beta-hemolytic streptococcal tonsillitis. After receiving oral penicillin, the clinical recovery was complete. Fever, tachycardia and chest discomfort resolved within a few days. Furthermore, enzyme levels and C-reactive protein returned to normal within eight days.

Topics: Acute Disease; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Echocardiography; Electrocardiography; Follow-Up Studies; Humans; Intensive Care Units; Male; Myocardial Infarction; Myocarditis; Nurses, Male; Penicillins; Pericarditis; Streptococcal Infections; Streptococcus pyogenes; Tonsillitis

Topics: Carrier State; Child; Demeclocycline; Dosage Forms; Drug Resistance; Drug Resistance, Microbial; Humans; Penicillin G; Penicillin V; Pharyngitis; Pharynx; Phosphates; Potassium; Respiratory Tract Infections; Streptococcal Infections; Tetracycline; Tonsillitis

Topics: Abdomen; Abscess; Bacteroides; Biliary Fistula; Bronchial Fistula; Candida; Drainage; Escherichia coli Infections; Humans; Liver Diseases; Penicillin V; Pneumonia; Radiography, Thoracic; Sputum; Streptococcal Infections; Sulfamethoxypyridazine; Surgical Procedures, Operative

Topics: Ampicillin; Animals; Anti-Bacterial Agents; Bacteria; Cat Diseases; Cats; Cattle; Cattle Diseases; Dog Diseases; Dogs; Drug Resistance; Drug Resistance, Microbial; Escherichia coli Infections; Microbiology; Milk; Pasteurella Infections; Penicillin G; Penicillin V; Pharmacology; Salmonella Infections; Salmonella Infections, Animal; Staphylococcal Infections; Streptococcal Infections; Swine; Swine Diseases

Topics: Diagnosis; Endocarditis, Bacterial; Endocarditis, Subacute Bacterial; Humans; Penicillin V; Streptococcal Infections; Streptococcus; Streptomycin

Topics: Absorption; Amino Acids; Animals; Ascorbic Acid; Aspirin; Barium; Dogs; Fats; Intestinal Absorption; Intestines; Monosaccharides; Penicillin V; Pharmacology; Rabbits; Rats; Research; Streptococcal Infections; Sulfisoxazole

Topics: Ampicillin; Biomedical Research; Blood; Dosage Forms; Endocarditis; Endocarditis, Bacterial; Humans; Injections, Intramuscular; Methicillin; Penicillanic Acid; Penicillin V; Penicillins; Pharmacology; Probenecid; Streptococcal Infections; Urine

Topics: Endocarditis, Bacterial; Humans; Penicillin V; Streptococcal Infections; Streptococcus; Streptomycin

Topics: Cross Infection; Epidemiology; Haemophilus influenzae; Penicillin G; Penicillin V; Penicillins; Pneumonia; Pneumonia, Pneumococcal; Respiratory Tract Infections; Staphylococcal Infections; Streptococcal Infections; Superinfection; Toxicology

Topics: Ethylenediamines; Humans; Penicillin G; Penicillin G Benzathine; Penicillin V; Penicillins; Pneumococcal Infections; Staphylococcal Infections; Streptococcal Infections

Topics: Humans; Penicillin G; Penicillin V; Penicillins; Staphylococcal Infections; Streptococcal Infections

Topics: Carrier State; Humans; Penicillin V; Penicillins; Schools; Streptococcal Infections; Streptococcus

Topics: General Practice; Penicillin V; Penicillins; Staphylococcal Infections; Streptococcal Infections

Topics: Laboratories; Penicillin V; Penicillins; Staphylococcal Infections; Streptococcal Infections