phenelzine has been researched along with Panic Disorder in 9 studies
Phenelzine: One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.
Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenelzine (PLZ), a nonselective monoamine oxidase inhibitor, is widely used in psychiatry for the treatment of panic disorder and depression." | 3.68 | Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: effects on monoamine oxidase, biogenic amines, and alpha 2-adrenoreceptor function. ( Baker, GB; Coutts, RT; Greenshaw, AJ; McKenna, KF, 1992) |
| "Because the other standard treatments of panic disorder, the SSRIs, have a slow onset of action, adding an extended-release benzodiazepine to the treatment regimen for the initial 6 to 8 weeks could serve as an effective bridge until the desired SSRI effect is realized." | 2.41 | The management of panic disorder. ( Sheehan, DV, 2002) |
| " There was no correlation of pyridoxal phosphate level with phenelzine daily dosage over the range of 30 mg to 90 mg." | 1.29 | Phenelzine reduces plasma vitamin B6. ( Bowen, RC; Hawkes, J; Hussein, M; Malcolm, DE; O'Donovan, C; Yu, PH, 1994) |
| "Posttraumatic stress disorder (PTSD) is frequently associated with major depressive disorder, and antidepressants have been reported to ameliorate PTSD symptoms in some patients." | 1.29 | Platelet imipramine binding in patients with posttraumatic stress disorder before and after phenelzine treatment. ( Abramovitz-Schnaider, P; Freudstein-Dan, A; Laor, N; Rehavi, M; Schujovitsky, A; Weizman, R; Wolmer, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheehan, DV | 1 |
| Buch, S | 1 |
| Wagner, M | 1 |
| Dassylva, B | 1 |
| Fontaine, R | 1 |
| Malcolm, DE | 1 |
| Yu, PH | 1 |
| Bowen, RC | 1 |
| O'Donovan, C | 1 |
| Hawkes, J | 1 |
| Hussein, M | 1 |
| Weizman, R | 1 |
| Laor, N | 1 |
| Schujovitsky, A | 1 |
| Wolmer, L | 1 |
| Abramovitz-Schnaider, P | 1 |
| Freudstein-Dan, A | 1 |
| Rehavi, M | 1 |
| Tanay, VA | 1 |
| Glencorse, TA | 1 |
| Greenshaw, AJ | 2 |
| Baker, GB | 2 |
| Bateson, AN | 1 |
| Gracious, BL | 1 |
| Wisner, KL | 1 |
| Griebel, G | 1 |
| Curet, O | 1 |
| Perrault, G | 1 |
| Sanger, DJ | 1 |
| McKenna, KF | 1 |
| Coutts, RT | 1 |
3 reviews available for phenelzine and Panic Disorder
| Article | Year |
|---|---|
The management of panic disorder.
Topics: Alprazolam; Antidepressive Agents, Tricyclic; Benzodiazepines; Clinical Trials as Topic; Delayed-Act | 2002 |
[Atypical depression: evolution toward a specific pharmacologic and efficacious treatment?].
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Controlled Clinical Trials as Topic; Depres | 1995 |
Phenelzine use throughout pregnancy and the puerperium: case report, review of the literature, and management recommendations.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Depressive Disorder, Major; Female; Humans; Monoa | 1997 |
6 other studies available for phenelzine and Panic Disorder
| Article | Year |
|---|---|
Successful use of phenelzine in treatment-resistant panic disorder.
Topics: Drug Resistance; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Panic Disorder; Phenelzine | 2007 |
Phenelzine reduces plasma vitamin B6.
Topics: Adolescent; Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Panic Disorder; Phe | 1994 |
Platelet imipramine binding in patients with posttraumatic stress disorder before and after phenelzine treatment.
Topics: Adult; Agoraphobia; Anxiety Disorders; Binding Sites; Blood Platelets; Depressive Disorder; Humans; | 1996 |
Chronic administration of antipanic drugs alters rat brainstem GABAA receptor subunit mRNA levels.
Topics: Animals; Anti-Anxiety Agents; Brain Stem; Buspirone; GABA Agonists; GABA-A Receptor Agonists; Imipra | 1996 |
Behavioral effects of phenelzine in an experimental model for screening anxiolytic and anti-panic drugs: correlation with changes in monoamine-oxidase activity and monoamine levels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Biogenic Monoamines; Bites and Stings; | 1998 |
Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: effects on monoamine oxidase, biogenic amines, and alpha 2-adrenoreceptor function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Biogenic Amines; Body Weight; Brain; | 1992 |