phenelzine has been researched along with Depression, Involutional in 16 studies
Phenelzine: One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.
Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When depression was accompanied by character disorder, the response was generally poor." | 6.64 | A comparison of electroconvulsive therapy and combined phenelzine-amitriptyline in refractory depression. ( Davidson, J; Law-Yone, B; Linnoila, M; McLeod, M, 1978) |
| " By study phase, Eight of 27 (30%) patients remitted with initial dosing of tranylcypromine up to 60 mg/d, 6/18 (33%) remitted with above PDR dosing of tranylcypromine up to 120 mg/d, and 1/6 (17%) to adding dextroamphetamine." | 2.79 | How treatable is refractory depression? ( Deliyannides, DA; McGrath, PJ; Stewart, JW, 2014) |
| "Up to a third of elderly patients with major depressive disorder do not respond to a first course of treatment with an antidepressant." | 2.73 | Lithium augmentation compared with phenelzine in treatment-resistant depression in the elderly: an open, randomized, controlled trial. ( Heeren, TJ; Kok, RM; Nolen, WA; Vink, D, 2007) |
| "When depression was accompanied by character disorder, the response was generally poor." | 2.64 | A comparison of electroconvulsive therapy and combined phenelzine-amitriptyline in refractory depression. ( Davidson, J; Law-Yone, B; Linnoila, M; McLeod, M, 1978) |
| "Evidence supports the use of MAOIs in major depressive disorder, certain anxiety disorders and, to lesser extent, bipolar depression." | 2.53 | MAOIs - does the evidence warrant their resurrection? ( Bosanac, P; Castle, D; Menkes, D, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 10 (62.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stewart, JW | 1 |
| Deliyannides, DA | 1 |
| McGrath, PJ | 1 |
| Menkes, D | 1 |
| Bosanac, P | 1 |
| Castle, D | 1 |
| Caudill, GB | 1 |
| Rosenquist, P | 1 |
| McCall, WV | 1 |
| Landolt, HP | 1 |
| Kelsoe, JR | 1 |
| Rapaport, MH | 1 |
| Gillin, JC | 1 |
| GREENBLATT, M | 1 |
| GROSSER, GH | 1 |
| WECHSLER, H | 1 |
| Vittengl, JR | 1 |
| Clark, LA | 1 |
| Jarrett, RB | 1 |
| Henkel, V | 1 |
| Mergl, R | 1 |
| Allgaier, AK | 1 |
| Kohnen, R | 1 |
| Möller, HJ | 1 |
| Hegerl, U | 1 |
| Sokolski, KN | 1 |
| Brown, BJ | 1 |
| Gorman, JM | 1 |
| Patkar, AA | 1 |
| Pae, CU | 1 |
| Masand, PS | 1 |
| Tulen, JH | 1 |
| Volkers, AC | 1 |
| van den Broek, WW | 1 |
| Bruijn, JA | 1 |
| Kok, RM | 1 |
| Vink, D | 1 |
| Heeren, TJ | 1 |
| Nolen, WA | 1 |
| Stewart, JT | 1 |
| Gracious, BL | 1 |
| Wisner, KL | 1 |
| Flint, AJ | 1 |
| Rifat, SL | 1 |
| Davidson, J | 1 |
| McLeod, M | 1 |
| Law-Yone, B | 1 |
| Linnoila, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Treatment for Refractory Depression With Sequential Trials of Tranylcypromine, Tranylcypromine Plus Dextroamphetamine, Tranylcypromine Plus Triiodothyronine.[NCT00296686] | Phase 4 | 31 participants (Actual) | Interventional | 2001-09-30 | Terminated (stopped due to Study is no longer funded.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for phenelzine and Depression, Involutional
| Article | Year |
|---|---|
MAOIs - does the evidence warrant their resurrection?
Topics: Anxiety Disorders; Bipolar Disorder; Depressive Disorder, Major; Depressive Disorder, Treatment-Resi | 2016 |
Treatment of depression with atypical features: a meta-analytic approach.
Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Humans; Moclobemide; Monoami | 2006 |
Transdermal selegiline: the new generation of monoamine oxidase inhibitors.
Topics: Administration, Cutaneous; Depressive Disorder, Major; Drug Interactions; Humans; Monoamine Oxidase | 2006 |
Phenelzine use throughout pregnancy and the puerperium: case report, review of the literature, and management recommendations.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Depressive Disorder, Major; Female; Humans; Monoa | 1997 |
6 trials available for phenelzine and Depression, Involutional
| Article | Year |
|---|---|
How treatable is refractory depression?
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Depressive Disorder, Major; Depress | 2014 |
Rapid tryptophan depletion reverses phenelzine-induced suppression of REM sleep.
Topics: Adult; Depressive Disorder, Major; Double-Blind Method; Electroencephalography; Female; Humans; Male | 2003 |
Validity of sudden gains in acute phase treatment of depression.
Topics: Acute Disease; Adult; Antidepressive Agents; Attitude; Awareness; Cognitive Behavioral Therapy; Comb | 2005 |
Sustained effects of phenelzine and tranylcypromine on orthostatic challenge in antidepressant-refractory depression.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; B | 2006 |
Lithium augmentation compared with phenelzine in treatment-resistant depression in the elderly: an open, randomized, controlled trial.
Topics: Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder, M | 2007 |
A comparison of electroconvulsive therapy and combined phenelzine-amitriptyline in refractory depression.
Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Amitriptyline; Depression; Depressive D | 1978 |
6 other studies available for phenelzine and Depression, Involutional
| Article | Year |
|---|---|
Could monoamine oxidase inhibitors promote asystole in electroconvulsive therapy patients?
Topics: Aged; Amlodipine; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Heart Arrest; Human | 2011 |
DIFFERENTIAL RESPONSE OF HOSPITALIZED DEPRESSED PATIENTS TO SOMATIC THERAPY.
Topics: Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, Major; Electroconvulsive The | 1964 |
Quetiapine for insomnia associated with refractory depression exacerbated by phenelzine.
Topics: Adult; Antipsychotic Agents; Depressive Disorder, Major; Dibenzothiazepines; Humans; Male; Monoamine | 2006 |
Leading the way: advances in the diagnosis, treatment, and management of neuropsychiatric illnesses.
Topics: Administration, Cutaneous; Administration, Topical; Brain; Depressive Disorder, Major; Humans; Menta | 2006 |
Not all monoamine oxidase inhibitors are created equal.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Majo | 2007 |
Maintenance treatment for recurrent depression in late life. A four-year outcome study.
Topics: Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Drug Therapy, Co | 2000 |