phenelzine has been researched along with Acute Liver Injury, Drug-Induced in 17 studies
Phenelzine: One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yogeeswari, P | 1 |
| Sriram, D | 1 |
| Thirumurugan, R | 1 |
| Raghavendran, JV | 1 |
| Sudhan, K | 1 |
| Pavana, RK | 1 |
| Stables, J | 1 |
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| GOLDBERG, LI | 1 |
| COOK, GC | 1 |
| SHERLOCK, S | 1 |
| KUSCH, T | 1 |
| Drayer, DE | 1 |
| Reidenberg, MM | 1 |
| Obata, T | 1 |
| Egashira, T | 1 |
| Yamanaka, Y | 1 |
| Faraj, BA | 1 |
| Schmidt, FH | 1 |
| Sarper, R | 1 |
| Camp, VM | 1 |
| Malveaux, E | 1 |
| Zimmerman, HJ | 1 |
| Ishak, KG | 1 |
| Bonkovsky, HL | 1 |
| Blanchette, PL | 1 |
| Schned, AR | 1 |
| Barberini, E | 1 |
| Malagoli, G | 1 |
2 reviews available for phenelzine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
MONOAMINE OXIDASE INHIBITORS. ADVERSE REACTIONS AND POSSIBLE MECHANISMS.
Topics: Amphetamine; Amphetamines; Chemical and Drug Induced Liver Injury; Headache; Hematologic Diseases; H | 1964 |
15 other studies available for phenelzine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzamides; Chemical and Drug Induced Liver | 2005 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
JAUNDICE AND ITS RELATION TO THERAPEUTIC AGENTS.
Topics: Alkaline Phosphatase; Antidepressive Agents; Aspartate Aminotransferases; Bilirubin; Chemical and Dr | 1965 |
[THE ACTIVITY OF HISTIDASE UNDER THE INFLUENCE OF EXPERIMENTAL LIVER DAMAGE AND PSYCHOPHARMACOLOGICAL AGENTS].
Topics: Bile Ducts; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorpromazine; | 1964 |
Clinical consequences of polymorphic acetylation of basic drugs.
Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Hum | 1977 |
Amine oxidase released into plasma of rats treated with hepatotoxin allyl formate.
Topics: Animals; Chemical and Drug Induced Liver Injury; Clonidine; Formates; Formic Acid Esters; Kinetics; | 1989 |
Tyramine neurotoxicity and first-pass brain technetium-99m-diethylenetriamine penta-acetic acid.
Topics: Animals; Brain; Cerebrovascular Circulation; Chemical and Drug Induced Liver Injury; Dogs; Dopamine; | 1987 |
The hepatic injury of monoamine oxidase inhibitors.
Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Humans; Hydrazines; Jaundice; Monoami | 1987 |
Severe liver injury due to phenelzine with unique hepatic deposition of extracellular material.
Topics: Chemical and Drug Induced Liver Injury; Extracellular Space; Humans; Liver; Male; Middle Aged; Phene | 1986 |
[On hepatocellular damage caused by MAOI drugs].
Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Monoamine Oxidase Inhibitors; Phenelzine; Ra | 1971 |