phenelfamycin-e and Clostridium-Infections

phenelfamycin-e has been researched along with Clostridium-Infections* in 1 studies

Other Studies

1 other study(ies) available for phenelfamycin-e and Clostridium-Infections

ArticleYear
Phenelfamycins, a novel complex of elfamycin-type antibiotics. III. Activity in vitro and in a hamster colitis model.
    The Journal of antibiotics, 1989, Volume: 42, Issue:1

    Phenelfamycins A, B, C, E, F and unphenelfamycin make up a recently isolated group of elfamycin-type antibiotics. All of the phenelfamycins were active against Gram-positive anaerobes, including Clostridium difficile. Phenelfamycin A was also active in vitro against Neisseria gonorrhoeae and Streptococci. Phenelfamycin A was found to be effective in prolonging the survival of hamsters in an animal model of C. difficile enterocolitis. After oral administration of phenelfamycin A to hamsters, antibiotic was detected in the caecal contents but not in the blood.

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Clostridium Infections; Cricetinae; Enterocolitis; Male; Mesocricetus; Vancomycin

1989