Page last updated: 2024-11-02

phenazopyridine and Urinary Retention

phenazopyridine has been researched along with Urinary Retention in 5 studies

Phenazopyridine: A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
phenazopyridine : A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.

Urinary Retention: Inability to empty the URINARY BLADDER with voiding (URINATION).

Research Excerpts

ExcerptRelevanceReference
"Previous studies have found that administration of phenazopyridine decreased short-term urinary retention following surgery but other more recent trials have shown mixed results."8.12The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery. ( Brong, K; Edenfield, A; Kesty, K; McSwain, S; Swift, S; Woll, A, 2022)
"Previous studies have found that administration of phenazopyridine decreased short-term urinary retention following surgery but other more recent trials have shown mixed results."4.12The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery. ( Brong, K; Edenfield, A; Kesty, K; McSwain, S; Swift, S; Woll, A, 2022)
"Three ureteral obstructions were identified intraoperatively and none in the postoperative period."2.82Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial. ( Alas, AN; Barber, M; Chadi, SA; Davila, GW; Espaillat-Rijo, L; Hurtado, EA; Siff, L; Vaish, S; Zimberg, S, 2016)
"We report a case of neurogenic bladder and chronic urinary retention associated with MDMA abuse."1.35Neurogenic bladder and chronic urinary retention associated with MDMA abuse. ( Barrueto, F; Beuerle, JR, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
McSwain, S1
Woll, A1
Edenfield, A1
Kesty, K1
Brong, K1
Swift, S1
Dubinskaya, A1
Sierra, T1
Taylor, DL1
Leung, K1
Hall, CD1
Flynn, MK1
Espaillat-Rijo, L1
Siff, L1
Alas, AN1
Chadi, SA1
Zimberg, S1
Vaish, S1
Davila, GW1
Barber, M1
Hurtado, EA1
Beuerle, JR1
Barrueto, F1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Phenazopyridine on Prolapse Surgery Voiding Trials[NCT03065075]Phase 3152 participants (Actual)Interventional2017-02-01Completed
Perioperative Administration of Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery[NCT03524339]Phase 2/Phase 3132 participants (Actual)Interventional2018-08-01Completed
Evaluation of Ureteral Jets on Cystoscopy: A Randomized Controlled Trial[NCT02476448]176 participants (Actual)Interventional2015-02-28Completed
The Use of Dye-less Cystoscopy in Assessing Urinary Tract Integrity During Hysterectomy[NCT05190939]276 participants (Actual)Interventional2018-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Postoperative Urinary Retention After Pelvic Organ Prolapse Surgery (AS-TREATED)

Rate of postoperative urinary retention after pelvic organ prolapse surgery as determined by those who failed a standardized void trial. A successful void trial is defined as a postvoid residual of less than half of the voided volume. (NCT03065075)
Timeframe: postoperative day 1

InterventionParticipants (Count of Participants)
Phenazopyridine28
No Phenazopyridine27

Number of Participants With Postoperative Urinary Retention After Pelvic Organ Prolapse Surgery (INTENT-TO-TREAT)

Rate of postoperative urinary retention after pelvic organ prolapse surgery as determined by those who failed a standardized void trial. A successful void trial is defined as a postvoid residual of less than half of the voided volume. (NCT03065075)
Timeframe: postoperative day 1

InterventionParticipants (Count of Participants)
Phenazopyridine30
No Phenazopyridine25

International Prostate Symptom Score

Total and subscale scores reported. Total score range 0-35, with 0 being less symptomatic and 35 being more symptomatic. Total score is sum of individual questions. Seven subgroups address incomplete bladder emptying, frequency, intermittency, urgency, weak stream, straining, nocturia. Each subgroup is scored 0-5 with 5 being most symptomatic. The last question is independent, rates quality of life from 0 (best) to 6 (worst) (NCT03524339)
Timeframe: Within 1 week of surgery

InterventionPoints (Median)
Placebo6
Tamsulosin7

Postoperative Urinary Retention

Failed voiding trial upon removal of catheter (NCT03524339)
Timeframe: Within 72 hours of surgery

InterventionParticipants (Count of Participants)
Placebo16
Tamsulosin5

Postoperative Urinary Tract Infection

Treated for urinary tract infection with antibiotics or urinalysis or urine culture suggests infection. (NCT03524339)
Timeframe: Within 6 weeks after surgery

InterventionParticipants (Count of Participants)
Placebo6
Tamsulosin4

Sent Home With Catheterization

Urinary retention that required homegoing catheterization (NCT03524339)
Timeframe: within 6 weeks of surgery

InterventionParticipants (Count of Participants)
Placebo7
Tamsulosin5

Number of Participants With Urinary Tract Infections

Medical records will be followed prospectively for 6 weeks to assess for incidence of urinary tract infections within different groups. (NCT02476448)
Timeframe: 6 weeks

InterventionParticipants (Count of Participants)
Normal Saline10
Dextrose 10%13
Phenazopyridine9
Sodium Fluorescein10

Trials

2 trials available for phenazopyridine and Urinary Retention

ArticleYear
The Effect of Phenazopyridine on Immediate Postoperative Voiding After Prolapse Surgery: A Randomized Controlled Trial.
    Female pelvic medicine & reconstructive surgery, 2021, 02-01, Volume: 27, Issue:2

    Topics: Anesthetics; Female; Humans; Middle Aged; Pelvic Organ Prolapse; Phenazopyridine; Postoperative Care

2021
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016
Intraoperative Cystoscopic Evaluation of Ureteral Patency: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Aged; Attitude of Health Personnel; Cystoscopy; F

2016

Other Studies

3 other studies available for phenazopyridine and Urinary Retention

ArticleYear
The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery.
    International urogynecology journal, 2022, Volume: 33, Issue:3

    Topics: Clinical Trials as Topic; Cystoscopy; Female; Humans; Phenazopyridine; Postoperative Complications;

2022
Commentary: The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery.
    International urogynecology journal, 2021, Volume: 32, Issue:6

    Topics: Anesthetics, Local; Humans; Phenazopyridine; Preoperative Care; Urinary Retention

2021
Neurogenic bladder and chronic urinary retention associated with MDMA abuse.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Anti-Infective Agents, Urinary; Bethanechol; Central Nervous S

2008