Page last updated: 2024-11-02

phenazopyridine and Postoperative Complications

phenazopyridine has been researched along with Postoperative Complications in 7 studies

Phenazopyridine: A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
phenazopyridine : A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.

Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Research Excerpts

ExcerptRelevanceReference
"Previous studies have found that administration of phenazopyridine decreased short-term urinary retention following surgery but other more recent trials have shown mixed results."8.12The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery. ( Brong, K; Edenfield, A; Kesty, K; McSwain, S; Swift, S; Woll, A, 2022)
"Phenazopyridine is a common, well-tolerated medication with minimal side effects."5.51Perioperative Hypoxia Secondary to Phenazopyridine-induced Methemoglobinemia in an Adolescent Patient Without Renal Insufficiency or Overdose: An Unusual Case. ( Kraft, KH; Shah, PK, 2019)
"Previous studies have found that administration of phenazopyridine decreased short-term urinary retention following surgery but other more recent trials have shown mixed results."4.12The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery. ( Brong, K; Edenfield, A; Kesty, K; McSwain, S; Swift, S; Woll, A, 2022)
"Phenazopyridine is a common, well-tolerated medication with minimal side effects."1.51Perioperative Hypoxia Secondary to Phenazopyridine-induced Methemoglobinemia in an Adolescent Patient Without Renal Insufficiency or Overdose: An Unusual Case. ( Kraft, KH; Shah, PK, 2019)
"Phenazopyridine was well tolerated by all patients, and its use was unequivocally documented in 32 subjects whose chart was reviewed to determine postoperative course."1.35Confirmation of ureteric patency during cystoscopy using phenazopyridine HCl: a low-cost approach. ( Harvey, MA; Hui, JYC; Johnston, SL, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
McSwain, S1
Woll, A1
Edenfield, A1
Kesty, K1
Brong, K1
Swift, S1
Grimes, CL1
Patankar, S1
Ryntz, T1
Philip, N1
Simpson, K1
Truong, M1
Young, C1
Advincula, A1
Madueke-Laveaux, OS1
Walters, R1
Ananth, CV1
Kim, JH1
Shah, PK1
Kraft, KH1
Sierra, T1
Taylor, DL1
Leung, K1
Hall, CD1
Flynn, MK1
Hui, JYC1
Harvey, MA1
Johnston, SL1
Norris, RD1
Sur, RL1
Springhart, WP1
Marguet, CG1
Mathias, BJ1
Pietrow, PK1
Albala, DM1
Preminger, GM1
Charles, JC1
Jones, GW1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Dye-less Cystoscopy in Assessing Urinary Tract Integrity During Hysterectomy[NCT05190939]276 participants (Actual)Interventional2018-07-01Completed
Effect of Phenazopyridine on Prolapse Surgery Voiding Trials[NCT03065075]Phase 3152 participants (Actual)Interventional2017-02-01Completed
A Prospective, Randomized, Pilot Study of Preoperative Anti-Inflammatory Therapy for Ureteral Stent Symptoms[NCT03638999]Early Phase 136 participants (Anticipated)Interventional2018-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Postoperative Urinary Retention After Pelvic Organ Prolapse Surgery (AS-TREATED)

Rate of postoperative urinary retention after pelvic organ prolapse surgery as determined by those who failed a standardized void trial. A successful void trial is defined as a postvoid residual of less than half of the voided volume. (NCT03065075)
Timeframe: postoperative day 1

InterventionParticipants (Count of Participants)
Phenazopyridine28
No Phenazopyridine27

Number of Participants With Postoperative Urinary Retention After Pelvic Organ Prolapse Surgery (INTENT-TO-TREAT)

Rate of postoperative urinary retention after pelvic organ prolapse surgery as determined by those who failed a standardized void trial. A successful void trial is defined as a postvoid residual of less than half of the voided volume. (NCT03065075)
Timeframe: postoperative day 1

InterventionParticipants (Count of Participants)
Phenazopyridine30
No Phenazopyridine25

Trials

3 trials available for phenazopyridine and Postoperative Complications

ArticleYear
Evaluating ureteral patency in the post-indigo carmine era: a randomized controlled trial.
    American journal of obstetrics and gynecology, 2017, Volume: 217, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Adult; Coloring Agents; Contrast Media; Cystoscop

2017
The Effect of Phenazopyridine on Immediate Postoperative Voiding After Prolapse Surgery: A Randomized Controlled Trial.
    Female pelvic medicine & reconstructive surgery, 2021, 02-01, Volume: 27, Issue:2

    Topics: Anesthetics; Female; Humans; Middle Aged; Pelvic Organ Prolapse; Phenazopyridine; Postoperative Care

2021
A prospective, randomized, double-blinded placebo-controlled comparison of extended release oxybutynin versus phenazopyridine for the management of postoperative ureteral stent discomfort.
    Urology, 2008, Volume: 71, Issue:5

    Topics: Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Mandelic Acids; Middle Aged;

2008

Other Studies

4 other studies available for phenazopyridine and Postoperative Complications

ArticleYear
The effect of preoperative phenazopyridine on short-term urinary retention following urogynecologic surgery.
    International urogynecology journal, 2022, Volume: 33, Issue:3

    Topics: Clinical Trials as Topic; Cystoscopy; Female; Humans; Phenazopyridine; Postoperative Complications;

2022
Perioperative Hypoxia Secondary to Phenazopyridine-induced Methemoglobinemia in an Adolescent Patient Without Renal Insufficiency or Overdose: An Unusual Case.
    Urology, 2019, Volume: 130

    Topics: Adolescent; Humans; Hypoxia; Male; Methemoglobinemia; Phenazopyridine; Postoperative Complications

2019
Confirmation of ureteric patency during cystoscopy using phenazopyridine HCl: a low-cost approach.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2009, Volume: 31, Issue:9

    Topics: Coloring Agents; Cystoscopy; Female; Gynecologic Surgical Procedures; Humans; Intraoperative Complic

2009
Comparative study of macrodantin and pyridium in controlling morbidity following surgery of the lower urinary tract.
    Journal of the National Medical Association, 1972, Volume: 64, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Azo Compounds; Bacterial Infections; Child; Child, Pres

1972