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phenazopyridine and Anemia, Hemolytic

phenazopyridine has been researched along with Anemia, Hemolytic in 29 studies

Phenazopyridine: A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
phenazopyridine : A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.

Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).

Research Excerpts

ExcerptRelevanceReference
"Two patients developed symptomatic methemoglobinemia and hemolytic anemia after treatment with phenazopyridine."7.66Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine. ( Hardy, WR; Jeffery, WH; Zelicoff, AP, 1982)
"An 18-year-old woman with no prior history of renal or hematologic dysfunction developed severe, acute methemoglobinemia after an overdose of phenazopyridine hydrochloride (Pyridium)."7.65Acute methemoglobinemia and hemolytic anemia with phenazopyridine: possible relation to acute renal failure. ( Bunn, HF; Nathan, DM; Siegel, AJ, 1977)
"Phenazopyridine is an azo dye, which exerts local anesthetic or analgesic action on urinary tract mucosa through an unknown mechanism."5.72Skin ulcers as a complication of short-term use of phenazopyridine in an old man: A case report. ( Elyasi, S; Tavanaee Sani, A; Zarei, B, 2022)
"Phenazopyridine is a commonly used urinary tract analgesic."5.28Methemoglobinemia and hemolytic anemia after phenazopyridine hydrochloride (Pyridium) administration in end-stage renal disease. ( Campbell, HT; Fincher, ME, 1989)
"Two patients developed symptomatic methemoglobinemia and hemolytic anemia after treatment with phenazopyridine."3.66Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine. ( Hardy, WR; Jeffery, WH; Zelicoff, AP, 1982)
"An 18-year-old woman with no prior history of renal or hematologic dysfunction developed severe, acute methemoglobinemia after an overdose of phenazopyridine hydrochloride (Pyridium)."3.65Acute methemoglobinemia and hemolytic anemia with phenazopyridine: possible relation to acute renal failure. ( Bunn, HF; Nathan, DM; Siegel, AJ, 1977)
"Phenazopyridine is an azo dye, which exerts local anesthetic or analgesic action on urinary tract mucosa through an unknown mechanism."1.72Skin ulcers as a complication of short-term use of phenazopyridine in an old man: A case report. ( Elyasi, S; Tavanaee Sani, A; Zarei, B, 2022)
" The chronic use of phenazopyridine accounted for all of these findings."1.33An over-the-counter omission. ( Scheurer, DB, 2006)
"Phenazopyridine is a commonly used urinary tract analgesic."1.28Methemoglobinemia and hemolytic anemia after phenazopyridine hydrochloride (Pyridium) administration in end-stage renal disease. ( Campbell, HT; Fincher, ME, 1989)
" Such products should be avoided in cats unless a safe, effective dosage for phenazopyridine can be established."1.26Phenazopyridine toxicosis in the cat. ( Harvey, JW; Kornick, HP, 1976)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199020 (68.97)18.7374
1990's5 (17.24)18.2507
2000's2 (6.90)29.6817
2010's1 (3.45)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Zarei, B1
Tavanaee Sani, A1
Elyasi, S1
Chang, LC1
Kuo, CW1
Chau, T1
Lin, SH1
GREENBERG, MS2
WONG, H1
GABOR, EP3
LOWENSTEIN, L1
DE LEEUW, NK1
Schrier, S1
Scheurer, DB1
Mercieca, JE1
Clarke, MF1
Phillips, ME1
Curtis, JR1
Tishler, M1
Abramov, A1
Virshup, DM1
Zinkham, WH1
Sirota, RL1
Caughey, WS1
Noonan, HM1
Kimbrell, M1
Johnson, WB1
Reuler, JB1
Jeffery, WH1
Zelicoff, AP1
Hardy, WR1
Schroeder, WA1
Powars, D1
Shelton, JB1
Shelton, JR1
Wilson, JB1
Huisman, TH1
Bedros, AA1
Siddiqui, MA1
Thomas, RJ1
Doddabele, S1
Karnad, AB1
Mishriki, YY1
Green, ED1
Zimmerman, RC1
Ghurabi, WH1
Colohan, DP1
Drysdale, HC1
Hellier, MD1
Bateman, CJ1
Nathan, DM1
Siegel, AJ1
Bunn, HF1
Harvey, JW1
Kornick, HP1
Kornowski, R1
Averbuch, M1
Jaffe, A1
Schwartz, D1
Levo, Y1
Ponte, CD1
Lewis, MJ1
Rogers, JS1
Fincher, ME1
Campbell, HT1
Galun, E1
Oren, R1
Glikson, M1
Friedlander, M1
Heyman, A1
Eisinger, AJ1
Jones, R1
Cohen, BL1
Bovasso, GJ1

Reviews

1 review available for phenazopyridine and Anemia, Hemolytic

ArticleYear
Phenazopyridine hydrochloride toxicity: a cause of drug-induced methemoglobinemia.
    JACEP, 1979, Volume: 8, Issue:10

    Topics: Acute Kidney Injury; Adolescent; Aged; Aminopyridines; Anemia, Hemolytic; Animals; Chemical and Drug

1979

Other Studies

28 other studies available for phenazopyridine and Anemia, Hemolytic

ArticleYear
Skin ulcers as a complication of short-term use of phenazopyridine in an old man: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022, Volume: 28, Issue:12

    Topics: Anemia, Hemolytic; Anesthetics, Local; Anti-Bacterial Agents; Azo Compounds; Humans; Losartan; Male;

2022
Phenazopyridine-induced hemolytic anemia in advanced kidney disease.
    Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:12

    Topics: Aged, 80 and over; Anemia, Hemolytic; Diabetes Complications; Humans; Kidney Failure, Chronic; Male;

2014
METHEMOGLOBINEMIA AND HEINZ BODY HEMOLYTIC ANEMIA DUE TO PHENAZOPYRIDINE HYDROCHLORIDE.
    The New England journal of medicine, 1964, Aug-27, Volume: 271

    Topics: Anemia, Hemolytic; Anemia, Hemolytic, Congenital; Azo Compounds; Chromium Isotopes; Erythrocytes; Gl

1964
HEMOLYTIC ANEMIA INDUCED BY PHENYLAZO-DIAMINO-PYRIDINE (PYRIDIUM).
    Canadian Medical Association journal, 1964, Oct-03, Volume: 91

    Topics: Anemia; Anemia, Hemolytic; Anti-Infective Agents, Local; Blood Transfusion; Geriatrics; Glucosephosp

1964
Oxidant hemolysis.
    Blood, 2003, Nov-01, Volume: 102, Issue:9

    Topics: Anemia, Hemolytic; Blood Cells; Erythrocytes, Abnormal; Female; Gentian Violet; Hemolysis; Histocyto

2003
An over-the-counter omission.
    Southern medical journal, 2006, Volume: 99, Issue:9

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Anesthetics, Local; Female; Humans; Middle Aged; Nonprescrip

2006
Acute hemolytic anaemia due to phenazopyridine hydrochloride in G-6-PD deficient subject.
    Lancet (London, England), 1982, Sep-04, Volume: 2, Issue:8297

    Topics: Aged; Aminopyridines; Anemia, Hemolytic; Glucosephosphate Dehydrogenase Deficiency; Humans; Male; Ph

1982
Phenazopyridine-induced hemolytic anemia in a patient with G6PD deficiency.
    Acta haematologica, 1983, Volume: 70, Issue:3

    Topics: Aged; Aminopyridines; Anemia, Hemolytic; Glucosephosphate Dehydrogenase Deficiency; Humans; Male; Ph

1983
Unique sensitivity of Hb Zürich to oxidative injury by phenazopyridine: reversal of the effects by elevating carboxyhemoglobin levels in vivo and in vitro.
    American journal of hematology, 1983, Volume: 14, Issue:4

    Topics: Adult; Aminopyridines; Anemia, Hemolytic; Carbon Monoxide; Carboxyhemoglobin; Female; Glutathione; H

1983
Phenazopyridine-induced hemolytic anemia.
    Urology, 1983, Volume: 21, Issue:6

    Topics: Aged; Aminopyridines; Anemia, Hemolytic; Dose-Response Relationship, Drug; Humans; Male; Phenazopyri

1983
Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:2

    Topics: Aged; Aminopyridines; Anemia, Hemolytic; Female; Humans; Hydroxylamines; Methemoglobinemia; Methylen

1982
An unusual phenotypic expression of Hb-Leiden.
    Biochemical genetics, 1982, Volume: 20, Issue:11-12

    Topics: Anemia, Hemolytic; Child; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Male; Phenazopyridine;

1982
Chronic severe hemolytic anemia from phenazopyridine.
    Annals of internal medicine, 1995, Jan-15, Volume: 122, Issue:2

    Topics: Anemia, Hemolytic; Chronic Disease; Humans; Phenazopyridine

1995
Chronic severe hemolytic anemia from phenazopyridine.
    Annals of internal medicine, 1995, Jan-15, Volume: 122, Issue:2

    Topics: Anemia, Hemolytic; Chronic Disease; Humans; Phenazopyridine

1995
Chronic severe hemolytic anemia related to surreptitious phenazopyridine abuse.
    Annals of internal medicine, 1994, Aug-15, Volume: 121, Issue:4

    Topics: Adult; Anemia, Hemolytic; Chronic Disease; Female; Humans; Phenazopyridine; Substance-Related Disord

1994
What's eating these red blood cells? Drug-induced "bite-cell" hemolytic anemia.
    Postgraduate medicine, 1998, Volume: 104, Issue:2

    Topics: Anemia, Hemolytic; Anesthetics, Local; Erythrocytes, Abnormal; Female; Humans; Middle Aged; Phenazop

1998
Inadequacy of information on side effects.
    British medical journal, 1978, Oct-07, Volume: 2, Issue:6143

    Topics: Aged; Aminopyridines; Anemia, Hemolytic; Drug Labeling; Female; Humans; Phenazopyridine

1978
Inadequacy of information of side effects.
    British medical journal, 1978, Dec-16, Volume: 2, Issue:6153

    Topics: Aminopyridines; Anemia, Hemolytic; Humans; Phenazopyridine

1978
Acute methemoglobinemia and hemolytic anemia with phenazopyridine: possible relation to acute renal failure.
    Archives of internal medicine, 1977, Volume: 137, Issue:11

    Topics: Acute Kidney Injury; Adolescent; Anemia, Hemolytic; Female; Humans; Methemoglobinemia; Phenazopyridi

1977
Phenazopyridine toxicosis in the cat.
    Journal of the American Veterinary Medical Association, 1976, Aug-01, Volume: 169, Issue:3

    Topics: Anemia, Hemolytic; Animals; Cat Diseases; Cats; Female; Heinz Bodies; Hematocrit; Jaundice; Male; Me

1976
Letter: Heinz body hemolytic anemia.
    Archives of internal medicine, 1976, Volume: 136, Issue:9

    Topics: Anemia, Hemolytic; Heinz Bodies; Humans; Phenazopyridine

1976
Heinz body hemolytic animea. "Bite cells" -a clue to diagnosis.
    Archives of internal medicine, 1976, Volume: 136, Issue:2

    Topics: Aged; Anemia, Hemolytic; Erythrocytes; Female; Heinz Bodies; Humans; Middle Aged; Phenazopyridine

1976
[Sedural toxicity].
    Harefuah, 1991, Mar-15, Volume: 120, Issue:6

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Female; Humans; Methemoglobinemia; Phenazopyridine

1991
Heinz-body hemolytic anemia associated with phenazopyridine and sulfonamide.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:2

    Topics: Administration, Oral; Adult; Aminopyridines; Anemia, Hemolytic; Drug Combinations; Drug Therapy, Com

1989
Methemoglobinemia and hemolytic anemia after phenazopyridine hydrochloride (Pyridium) administration in end-stage renal disease.
    Southern medical journal, 1989, Volume: 82, Issue:3

    Topics: Acute Disease; Adult; Aminopyridines; Anemia, Hemolytic; Hemolysis; Humans; Kidney Failure, Chronic;

1989
Phenazopyridine-induced hemolytic anemia in G-6-PD deficiency.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:11

    Topics: Adult; Aminopyridines; Anemia, Hemolytic; Female; Glomerulonephritis, IGA; Glucosephosphate Dehydrog

1987
Phenazopyridine-hydrochloride haemolysis.
    Lancet (London, England), 1969, Jan-18, Volume: 1, Issue:7586

    Topics: Aged; Anemia, Hemolytic; Anti-Infective Agents, Urinary; Female; Humans; Phenazopyridine

1969
Acquired methemoglobinemia and hemolytic anemia following excessive pyridium (phenazopyridine hydrochloride) ingestion.
    Clinical pediatrics, 1971, Volume: 10, Issue:9

    Topics: Analgesics; Anemia, Hemolytic; Anesthetics, Local; Azo Compounds; Female; Humans; Hypoxia; Infant; M

1971