phenazopyridine has been researched along with Acute Kidney Injury in 15 studies
Phenazopyridine: A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
phenazopyridine : A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 19-year-old woman with no history of renal or hematologic dysfunction developed methemoglobinemia, muscle damage, rhabdomyolysis and severe acute renal failure after an overdose of phenazopyridine hydrochloride (pyridium)." | 7.67 | Methemoglobinemia, muscle damage and renal failure complicating phenazopyridine overdose. ( Gavish, D; Gottehrer, N; Israeli, A; Kleinman, Y; Knobler, H, 1986) |
| "An 18-year-old woman with no prior history of renal or hematologic dysfunction developed severe, acute methemoglobinemia after an overdose of phenazopyridine hydrochloride (Pyridium)." | 7.65 | Acute methemoglobinemia and hemolytic anemia with phenazopyridine: possible relation to acute renal failure. ( Bunn, HF; Nathan, DM; Siegel, AJ, 1977) |
| "A 19-year-old woman with no history of renal or hematologic dysfunction developed methemoglobinemia, muscle damage, rhabdomyolysis and severe acute renal failure after an overdose of phenazopyridine hydrochloride (pyridium)." | 3.67 | Methemoglobinemia, muscle damage and renal failure complicating phenazopyridine overdose. ( Gavish, D; Gottehrer, N; Israeli, A; Kleinman, Y; Knobler, H, 1986) |
| "An 18-year-old woman with no prior history of renal or hematologic dysfunction developed severe, acute methemoglobinemia after an overdose of phenazopyridine hydrochloride (Pyridium)." | 3.65 | Acute methemoglobinemia and hemolytic anemia with phenazopyridine: possible relation to acute renal failure. ( Bunn, HF; Nathan, DM; Siegel, AJ, 1977) |
| "Phenazopyridine (Pyridium) is a commonly used urinary tract analgesic." | 2.43 | Acute renal failure due to phenazopyridine (Pyridium) overdose: case report and review of the literature. ( Abitbol, C; Berho, ME; Chandar, J; Espinoza, V; Onder, AM; Zilleruelo, G, 2006) |
| " The chronic use of phenazopyridine accounted for all of these findings." | 1.33 | An over-the-counter omission. ( Scheurer, DB, 2006) |
| "This is an unusual case of acute renal failure caused by an overdose of a drug, commonly prescribed for urinary tract infections." | 1.32 | [Acute renal failure caused by phenazopyridine]. ( Vega, J, 2003) |
| "Phenazopyridine-induced acute renal failure is rare, but its early recognition is important so that additional nephrotoxicity from studies using roentgenographic contrast material may be avoided in patients with this problem." | 1.26 | Additive nephrotoxicity from roentgenographic contrast media. Its occurrence in phenazopyridine-induced acute renal failure. ( Engle, JE; Schoolwerth, AC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atreya, MR | 1 |
| Al Jaberi, N | 1 |
| Claes, DJ | 1 |
| Volovelsky, O | 1 |
| Vega, J | 1 |
| Onder, AM | 1 |
| Espinoza, V | 1 |
| Berho, ME | 1 |
| Chandar, J | 1 |
| Zilleruelo, G | 1 |
| Abitbol, C | 1 |
| Scheurer, DB | 1 |
| Rule, KA | 1 |
| Biggs, AW | 1 |
| Engle, JE | 1 |
| Schoolwerth, AC | 1 |
| Green, ED | 1 |
| Zimmerman, RC | 1 |
| Ghurabi, WH | 1 |
| Colohan, DP | 1 |
| Qureshi, N | 1 |
| Hedger, RW | 1 |
| Cahan, DH | 1 |
| Feinfeld, DA | 1 |
| Ranieri, R | 1 |
| Lipner, HI | 1 |
| Avram, MM | 1 |
| Nathan, DM | 1 |
| Siegel, AJ | 1 |
| Bunn, HF | 1 |
| Kornowski, R | 1 |
| Averbuch, M | 1 |
| Jaffe, A | 1 |
| Schwartz, D | 1 |
| Levo, Y | 1 |
| Sharon, M | 1 |
| Puente, G | 1 |
| Cohen, LB | 1 |
| Gavish, D | 1 |
| Knobler, H | 1 |
| Gottehrer, N | 1 |
| Israeli, A | 1 |
| Kleinman, Y | 1 |
| Eybel, CE | 1 |
| Armbruster, KF | 1 |
| Ing, TS | 1 |
2 reviews available for phenazopyridine and Acute Kidney Injury
| Article | Year |
|---|---|
Acute renal failure due to phenazopyridine (Pyridium) overdose: case report and review of the literature.
Topics: Acetylcysteine; Acute Kidney Injury; Adolescent; Carnitine; Female; HIV Infections; Humans; Infectio | 2006 |
Phenazopyridine hydrochloride toxicity: a cause of drug-induced methemoglobinemia.
Topics: Acute Kidney Injury; Adolescent; Aged; Aminopyridines; Anemia, Hemolytic; Animals; Chemical and Drug | 1979 |
13 other studies available for phenazopyridine and Acute Kidney Injury
| Article | Year |
|---|---|
Case 6: Skin Discoloration, Methemoglobinemia, and Acute Interstitial Nephritis in a 15-year-old Girl.
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Analgesics; Female; Humans; Methemoglobinemia; Nephr | 2017 |
[Acute renal failure caused by phenazopyridine].
Topics: Acute Kidney Injury; Adult; Anesthetics, Local; Female; Humans; Phenazopyridine | 2003 |
An over-the-counter omission.
Topics: Acute Kidney Injury; Anemia, Hemolytic; Anesthetics, Local; Female; Humans; Middle Aged; Nonprescrip | 2006 |
Transient renal failure following phenazopyridine overdose.
Topics: Acute Kidney Injury; Adolescent; Aminopyridines; Female; Humans; Methemoglobinemia; Phenazopyridine | 1984 |
Additive nephrotoxicity from roentgenographic contrast media. Its occurrence in phenazopyridine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Aminopyridines; Diatrizoate; Female; Humans; Iopanoic Acid; Kidney; Phena | 1981 |
Phenylazopyridine (Pyridium) and acute renal failure.
Topics: Acute Kidney Injury; Adult; Aminopyridines; Female; Humans; Phenazopyridine | 1979 |
Phenazopyridine overdose and renal failure.
Topics: Acute Kidney Injury; Aminopyridines; Humans; Phenazopyridine | 1979 |
Renal failure in phenazopyridine overdose.
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Aminopyridines; Diagnosis, Differential; Female; Hep | 1978 |
Acute methemoglobinemia and hemolytic anemia with phenazopyridine: possible relation to acute renal failure.
Topics: Acute Kidney Injury; Adolescent; Anemia, Hemolytic; Female; Humans; Methemoglobinemia; Phenazopyridi | 1977 |
[Sedural toxicity].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Female; Humans; Methemoglobinemia; Phenazopyridine | 1991 |
Phenazopyridine (Pyridium) poisoning: possible toxicity of methylene blue administration in renal failure.
Topics: Acute Kidney Injury; Aminopyridines; Hemolysis; Humans; Male; Methemoglobinemia; Methylene Blue; Mid | 1986 |
Methemoglobinemia, muscle damage and renal failure complicating phenazopyridine overdose.
Topics: Acute Kidney Injury; Adult; Aminopyridines; Creatinine; Female; Humans; Methemoglobinemia; Muscles; | 1986 |
Skin pigmentation and acute renal failure in a patient receiving phenazophyridine therapy.
Topics: Acute Kidney Injury; Administration, Oral; Aged; Blood Urea Nitrogen; Creatinine; Female; Humans; Ph | 1974 |