phenazopyridine has been researched along with Ache in 7 studies
Phenazopyridine: A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
phenazopyridine : A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare pain scores with preprocedure oral phenazopyridine vs intravesical lidocaine in women undergoing intradetrusor onabotulinumtoxinA injections for idiopathic overactive bladder." | 5.51 | Oral phenazopyridine vs intravesical lidocaine for bladder onabotulinumtoxinA analgesia: a randomized controlled trial. ( Jacobs, KM; Raker, CA; Siddique, M; Stewart, LE; Sung, VW, 2022) |
| "The intake of phenazopyridine allows to reduce pain intensity during and after cystoscopy and alleviate pain during first urination." | 5.34 | [Influence of phenazopyridine on the well-being of patients during and after cystoscopy]. ( Makushin, DG; Mirzakadiev, AA; Tsukanov, AY; Zolotov, IA, 2020) |
| "We sought to determine if phenazopyridine improves pain in catheterized patients recovering from gynecologic surgery." | 5.15 | Phenazopyridine does not improve catheter discomfort following gynecologic surgery. ( Anderson, C; Brubaker, L; Chimhanda, M; Galloway, S; Sinacore, J; Sloan, J, 2011) |
| "and purpose: Phenazopyridine (PAP) is an over-the-counter drug widely used to provide symptomatic relief of bladder pain in conditions such as cystitis or bladder pain syndrome (BPS)." | 4.31 | Inhibition of TRPM8 by the urinary tract analgesic drug phenazopyridine. ( Bazeli, B; Daniluk, J; Everaerts, W; Freitas, ACN; Janssens, A; Luyts, N; Mulier, M; Voets, T, 2023) |
| "Phenazopyridine has been associated with methemoglobinemia in patients who have received an overdose, have decreased renal function, or are discovered to be unusually susceptible to the drug (ie, they may have an undetected NADH methemoglobin reductase deficiency)." | 3.68 | Acquired methemoglobinemia from multiple oxidants. ( Bailey, MK; Baker, JD; Conroy, JM; Dorman, BH; Martin, WJ, 1993) |
| "Phenazopyridine HCl is a bladder analgesic." | 2.73 | Use of phenazopyridine for reducing discomfort during embryo transfer. ( Allsworth, JE; Frishman, GN; Gannon, JB; Wright, KP, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Stewart, LE | 1 |
| Siddique, M | 1 |
| Jacobs, KM | 1 |
| Raker, CA | 1 |
| Sung, VW | 1 |
| Luyts, N | 1 |
| Daniluk, J | 1 |
| Freitas, ACN | 1 |
| Bazeli, B | 1 |
| Janssens, A | 1 |
| Mulier, M | 1 |
| Everaerts, W | 1 |
| Voets, T | 1 |
| Tsukanov, AY | 1 |
| Makushin, DG | 1 |
| Mirzakadiev, AA | 1 |
| Zolotov, IA | 1 |
| Anderson, C | 1 |
| Chimhanda, M | 1 |
| Sloan, J | 1 |
| Galloway, S | 1 |
| Sinacore, J | 1 |
| Brubaker, L | 1 |
| Frishman, GN | 1 |
| Allsworth, JE | 1 |
| Gannon, JB | 1 |
| Wright, KP | 1 |
| Conroy, JM | 1 |
| Baker, JD | 1 |
| Martin, WJ | 1 |
| Bailey, MK | 1 |
| Dorman, BH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oral Phenazopyridine Versus Intravesical Lidocaine for Office OnabotulinumtoxinA Analgesia: A Randomized Controlled Trial[NCT03755089] | Phase 4 | 110 participants (Anticipated) | Interventional | 2018-11-01 | Recruiting | ||
| THE CAT(H) STUDY CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial A CREST 2010 Project[NCT00771173] | Phase 4 | 258 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The VAS measures bladder pain on a straight line from 0 to 10 in centimeters, where a mark of zero indicates no pain and a mark of 10 indicates worst possible pain. Mean VAS score was recorded for participants in the active treatment and placebo cohorts. (NCT00771173)
Timeframe: 24 hours
| Intervention | centimeters (Mean) |
|---|---|
| Active Agent Group | 0.95 |
| Placebo Group | 0.97 |
4 trials available for phenazopyridine and Ache
| Article | Year |
|---|---|
Oral phenazopyridine vs intravesical lidocaine for bladder onabotulinumtoxinA analgesia: a randomized controlled trial.
Topics: Adult; Analgesia; Botulinum Toxins, Type A; Female; Humans; Lidocaine; Pain; Phenazopyridine; Treatm | 2022 |
[Influence of phenazopyridine on the well-being of patients during and after cystoscopy].
Topics: Cystoscopy; Humans; Pain; Phenazopyridine; Ureter | 2020 |
Phenazopyridine does not improve catheter discomfort following gynecologic surgery.
Topics: Anesthetics, Local; Female; Gynecologic Surgical Procedures; Humans; Middle Aged; Pain; Phenazopyrid | 2011 |
Use of phenazopyridine for reducing discomfort during embryo transfer.
Topics: Adult; Double-Blind Method; Embryo Transfer; Female; Humans; Pain; Pain Measurement; Phenazopyridine | 2007 |
3 other studies available for phenazopyridine and Ache
| Article | Year |
|---|---|
Inhibition of TRPM8 by the urinary tract analgesic drug phenazopyridine.
Topics: Animals; Calcium; Cricetinae; Cricetulus; Fura-2; Ganglia, Spinal; HEK293 Cells; Humans; Menthol; Mi | 2023 |
Urinary tract infection drug helps pain, hinders cure.
Topics: Anesthetics, Local; Female; Humans; Pain; Phenazopyridine; Urinary Tract Infections | 2004 |
Acquired methemoglobinemia from multiple oxidants.
Topics: Administration, Topical; Adult; Analgesia, Epidural; Blood Gas Analysis; Bupivacaine; Cytochrome-B(5 | 1993 |