phenanthridone has been researched along with Necrosis in 2 studies
phenanthridone: coal tar derivative; structure given in first source
phenanthridone : A member of the class of phenanthridines that is phenanthridine with an oxo substituent at position 6. A poly(ADP-ribose) polymerase (PARP) inhibitor, it has been shown to exhibit immunosuppressive activity.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined the neuroprotective effects of the PARP inhibitors benzamide, 6(5H)-phenanthridinone, and 3,4-dihydro-5-[4-1(1-piperidinyl)buthoxy]-1(2H)-isoquinolinone in three rodent models of cerebral ischemia." | 3.71 | Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia. ( Chiarugi, A; Cozzi, A; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F; Picca, R; Romagnoli, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banasik, M | 1 |
| Stedeford, T | 1 |
| Ueda, K | 1 |
| Muro-Cacho, C | 1 |
| Su, PH | 1 |
| Tanaka, S | 1 |
| Harbison, RD | 1 |
| Moroni, F | 1 |
| Meli, E | 1 |
| Peruginelli, F | 1 |
| Chiarugi, A | 1 |
| Cozzi, A | 1 |
| Picca, R | 1 |
| Romagnoli, P | 1 |
| Pellicciari, R | 1 |
| Pellegrini-Giampietro, DE | 1 |
2 other studies available for phenanthridone and Necrosis
| Article | Year |
|---|---|
Hepatoprotective effects of 6(5H)-phenanthridinone from chemical-induced centrilobular necrosis.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Carbon Tetrachloride Poisonin | 2004 |
Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia.
Topics: Animals; Apoptosis; Benzamides; Brain Ischemia; Caspase 3; Caspases; Cell Death; Cell Line; Cerebral | 2001 |