phenanthridone has been researched along with Cerebral Ischemia in 4 studies
phenanthridone: coal tar derivative; structure given in first source
phenanthridone : A member of the class of phenanthridines that is phenanthridine with an oxo substituent at position 6. A poly(ADP-ribose) polymerase (PARP) inhibitor, it has been shown to exhibit immunosuppressive activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined the neuroprotective effects of the PARP inhibitors benzamide, 6(5H)-phenanthridinone, and 3,4-dihydro-5-[4-1(1-piperidinyl)buthoxy]-1(2H)-isoquinolinone in three rodent models of cerebral ischemia." | 3.71 | Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia. ( Chiarugi, A; Cozzi, A; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F; Picca, R; Romagnoli, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferraris, D | 2 |
| Ko, YS | 1 |
| Pahutski, T | 1 |
| Ficco, RP | 2 |
| Serdyuk, L | 1 |
| Alemu, C | 1 |
| Bradford, C | 1 |
| Chiou, T | 1 |
| Hoover, R | 1 |
| Huang, S | 1 |
| Lautar, S | 2 |
| Liang, S | 2 |
| Lin, Q | 2 |
| Lu, MX | 2 |
| Mooney, M | 1 |
| Morgan, L | 2 |
| Qian, Y | 1 |
| Tran, S | 1 |
| Williams, LR | 2 |
| Wu, QY | 1 |
| Zhang, J | 2 |
| Zou, Y | 1 |
| Kalish, V | 1 |
| Dain, D | 1 |
| Ginski, M | 1 |
| Lee-Wisdom, K | 1 |
| Thomas, B | 1 |
| Zhou, Y | 1 |
| Kalish, VJ | 1 |
| Chiarugi, A | 2 |
| Meli, E | 2 |
| Calvani, M | 1 |
| Picca, R | 2 |
| Baronti, R | 1 |
| Camaioni, E | 1 |
| Costantino, G | 1 |
| Marinozzi, M | 1 |
| Pellegrini-Giampietro, DE | 2 |
| Pellicciari, R | 2 |
| Moroni, F | 2 |
| Peruginelli, F | 1 |
| Cozzi, A | 1 |
| Romagnoli, P | 1 |
4 other studies available for phenanthridone and Cerebral Ischemia
| Article | Year |
|---|---|
Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries.
Topics: Animals; Aza Compounds; Brain Ischemia; Dogs; Enzyme Inhibitors; Haplorhini; Humans; In Vitro Techni | 2003 |
Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries.
Topics: Animals; Benzimidazoles; Benzodiazepines; Binding Sites; Brain Ischemia; Caco-2 Cells; Diabetes Mell | 2003 |
Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia.
Topics: Animals; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Isoquinolines; Mice; Neuroprotecti | 2003 |
Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia.
Topics: Animals; Apoptosis; Benzamides; Brain Ischemia; Caspase 3; Caspases; Cell Death; Cell Line; Cerebral | 2001 |